Search Results - "Allen, Shona W."

Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS by Mortberg, Meredith A, Zhao, Hien T, Reidenbach, Andrew G, Gentile, Juliana E, Kuhn, Eric, O'Moore, Jill, Dooley, Patrick M, Connors, Theresa R, Mazur, Curt, Allen, Shona W, Trombetta, Bianca A, McManus, Alison, Moore, Matthew R, Liu, Jiewu, Cabin, Deborah E, Kordasiewicz, Holly B, Mathews, Joel, Arnold, Steven E, Vallabh, Sonia M, Minikel, Eric Vallabh

“…Prion protein (PrP) concentration controls the kinetics of prion replication and is a genetically and pharmacologically validated therapeutic target for prion…”
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Fluid Biomarkers in Individuals at Risk for Genetic Prion Disease up to Disease Conversion by Vallabh, Sonia M, Mortberg, Meredith A, Allen, Shona W, Kupferschmid, Ashley C, Kivisakk, Pia, Hammerschlag, Bruno L, Bolling, Anna, Trombetta, Bianca A, Devitte-McKee, Kelli, Ford, Abaigeal M, Sather, Lauren E, Duffy, Griffin, Rivera, Ashley, Gerber, Jessica, McManus, Alison J, Minikel, Eric V, Arnold, Steven E

“…To longitudinally characterize disease-relevant CSF and plasma biomarkers in individuals at risk for genetic prion disease up to disease conversion. This…”
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Evaluating the biological variability of blood‐based biomarkers for use in clinical trials by Trombetta, Bianca A., Allen, Shona W., El‐Mufti, Leena H., Riley, Misha M., Ramirez, Christopher E., Weik, Molly, Carlyle, Becky C., Kivisäkk, Pia, Arnold, Steven E.

“…Background Blood‐based biomarkers offer the possibility of inexpensive, minimally invasive, and accessible diagnostic tools for Alzheimer’s Disease (AD). In…”
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