Search Results - "Allen, Peter S."

T2 measurement and quantification of glutamate in human brain in vivo by Choi, Changho, Coupland, Nicholas J., Bhardwaj, Paramjit P., Kalra, Sanjay, Casault, Colin A., Reid, Kim, Allen, Peter S.

“…The proton NMR transverse relaxation time T2 of glutamate (Glu) in human brain was measured by means of spectrally selective refocusing at 3.0 T in vivo. An…”
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The Destruction of Memory Tim Slade, dir. 85 min. English. New York: Icarus Films, 2017 by Allen, Peter S.

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Spatial Profiling of the Corticospinal Tract in Amyotrophic Lateral Sclerosis Using Diffusion Tensor Imaging by Wong, John C.T., Concha, Luis, Beaulieu, Christian, Johnston, Wendy, Allen, Peter S., Kalra, Sanjay

“…ABSTRACT Background and Purpose: Diffusion tensor imaging (DTI) was used as a noninvasive method to evaluate the anatomy of the corticospinal tract (CST) and…”
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Increased Glutamate Levels in the Medial Prefrontal Cortex in Patients with Postpartum Depression by MCEWENS, Alyssa M, TA BURGESS, Denee, LEMELLEDO, Jean-Michel, HANSTOCK, Christopher C, SERES, Peter, KHALILI, Panteha, NEWMAN, Stephen C, BAKER, Glen B, MITCHELL, Nicholas D, KHUDABUX-DER, Janisse, ALLEN, Peter S

“…The medial prefrontal cortex (MPFC) is a key brain area in depressive symptomatology; specifically, glutamate (Glu) has been reported to play a significant…”
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A dual-tuned transceive resonator for (13) C{(1) H} MRS: two open coils in one by Yahya, Atiyah, De Zanche, Nicola, Allen, Peter S

“…Proton-decoupled, (13) C nuclear MRS experiments require a RF coil that operates at the Larmor frequencies of both (13) C and (1) H. In this work, we designed,…”
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A dual-tuned transceive resonator for 13C{1H} MRS: two open coils in one by Yahya, Atiyah, De Zanche, Nicola, Allen, Peter S.

“…Proton‐decoupled, 13C nuclear MRS experiments require a RF coil that operates at the Larmor frequencies of both 13C and 1H. In this work, we designed, built…”
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Decreased Prefrontal Myo-Inositol in Major Depressive Disorder by Coupland, Nick J., Ogilvie, Catherine J., Hegadoren, Kathleen M., Seres, Peter, Hanstock, Chris C., Allen, Peter S.

“…Postmortem studies have shown robust prefrontal cortex glial losses and more subtle neuronal changes in major depressive disorder (MDD). Earlier proton…”
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Enhancement of spectral editing efficacy of multiple quantum filters in in vivo proton magnetic resonance spectroscopy by Kim, Hyeonjin, Thompson, Richard B., Allen, Peter S.

“…[Display omitted] ► The role of the phase of the 2nd 90° pulse in multiple quantum filters was evaluated. ► Product operator and numerical methods were used in…”
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Contamination of single-voxel multiple quantum filters by external water signals arising from intermolecular multiple quantum coherences by Thompson, Richard B., Allen, Peter S.

“…Multiple‐quantum filtered pulse sequences simplify overlapping metabolite spectra by the elimination of peaks from uncoupled spin species, most notably from…”
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Determinants of anisotropic water diffusion in nerves by Beaulieu, C, Allen, P S

“…We report NMR diffusion measurements of water in three central nervous system models, namely the nonmyelinated olfactory, and the myelinated trigeminal and…”
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Measurement of GABA and contaminants in gray and white matter in human brain in vivo by Choi, Changho, Bhardwaj, Paramjit P., Kalra, Sanjay, Casault, Colin A., Yasmin, Umme S., Allen, Peter S., Coupland, Nicholas J.

“…A preliminary study of discrimination between GABA and macromolecules (MMs) in human brain by proton double quantum filtering (DQF) at 3.0T in vivo is…”
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Clinical NOE 13C MRS for neuropsychiatric disorders of the frontal lobe by Sailasuta, Napapon, Robertson, Larry W., Harris, Kent C., Gropman, Andrea L., Allen, Peter S., Ross, Brian D.

“…In this communication, a scheme is described whereby in vivo 13C MRS can safely be performed in the frontal lobe, a human brain region hitherto precluded on…”
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Proton spectral editing for discrimination of lactate and threonine 1.31 ppm resonances in human brain in vivo by Choi, Changho, Coupland, Nicholas J., Kalra, Sanjay, Bhardwaj, Paramjit P., Malykhin, Nikolai, Allen, Peter S.

“…A single‐voxel proton NMR J‐difference editing method for discriminating between the 1.31 ppm resonances of lactate (Lac) and threonine (Thr) in human brain in…”
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Measurement of brain glutamate and glutamine by spectrally-selective refocusing at 3 tesla by Choi, Changho, Coupland, Nicholas J., Bhardwaj, Paramjit P., Malykhin, Nikolai, Gheorghiu, Dan, Allen, Peter S.

“…A new single‐voxel proton NMR spectrally‐selective refocusing method for measuring glutamate (Glu) and glutamine (Gln) in the human brain in vivo at 3T is…”
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Effect of strong homonuclear proton coupling on localized (13)C detection using PRESS by Yahya, Atiyah, Allen, Peter S

“…The effect of strong homonuclear proton coupling on (13)C incorporation measurements by either indirect or direct means was investigated (and illustrated with…”
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Water diffusion in the giant axon of the squid: implications for diffusion-weighted MRI of the nervous system by Beaulieu, C, Allen, P S

“…To clarify the result that marked diffusional anisotropy had been found in nomyelinated nerve, and in completion of an evaluation of the role of all…”
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Changes in water diffusion due to Wallerian degeneration in peripheral nerve by Beaulieu, C, Does, M D, Snyder, R E, Allen, P S

“…The authors report NMR measurements of the changes in water diffusion brought about by in vivo Wallerian degeneration due to either crush- or tie-injuries in…”
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Response of metabolites with coupled spins to the STEAM sequence by Thompson, Richard B., Allen, Peter S.

“…This article demonstrates that a numerical solution of the full quantum mechanical equations for all metabolites with coupled spins is an efficient and…”
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GABA X2 multiplet measured pre- and post-administration of vigabatrin in human brain by Hanstock, Christopher C., Coupland, Nicholas J., Allen, Peter S.

“…This work demonstrates, in solution and in human brain at 3 tesla, that the X2‐multiplet of the A2M2X2 proton spin system of GABA at 2.315 ppm can be readily…”
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Variability of metabolite yield using STEAM or PRESS sequences in vivo at 3.0 T, illustrated with myo-inositol by Kim, Hyeonjin, Thompson, Richard B., Hanstock, Christopher C., Allen, Peter S.

“…Using as an example the myo‐inositol (mI) band at ∼3.6 ppm in the proton spectrum from brain, an evaluation is presented that highlights the difficulties of…”
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