Search Results - "Allen, Kyle"

The clearance and biodistribution of magnetic composite nanoparticles in healthy and osteoarthritic rat knees by Partain, Brittany D., Unni, Mythreyi, Rinaldi, Carlos, Allen, Kyle D.

“…Intra-articular injections are the most direct route for administering osteoarthritis (OA) therapies, yet how drug carriers distribute within the joint remains…”
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Hypertension contributes to exacerbated osteoarthritis pathophysiology in rats in a sex-dependent manner by Yeater, Taylor D, Griffith, Jacob L, Cruz, Carlos J, Patterson, Folly M, Aldrich, Jessica L, Allen, Kyle D

“…Hypertension is a common comorbidity of osteoarthritis (OA) with known autonomic dysregulation; thus, the autonomic nervous system may provide a shared…”
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Recommendations for the analysis of rodent gait data to evaluate osteoarthritis treatments by Chan, Kiara M., Bowe, Markia T., Allen, Kyle D.

“…Behavioral assays of animal pain and disability can increase the clinical relevance of a preclinical study. However, pain and symptoms are difficult to measure…”
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Age alters gait compensations following meniscal injury in male rats by Chan, Kiara M., Yeater, Taylor D., Allen, Kyle D.

“…With age, susceptibility to osteoarthritis (OA) and OA‐related pain and disability increases. Like in OA patients, gait patterns in rodent OA models shift to…”
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Gait Analysis Methods for Rodent Models of Arthritic Disorders: Reviews and Recommendations by Lakes, Emily H, Allen, Kyle D., Ph.D

“…Summary Gait analysis is a useful tool to understand behavioral changes in preclinical arthritis models. While observational scoring and spatiotemporal gait…”
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Design Principles of Perovskites for Thermochemical Oxygen Separation by Ezbiri, Miriam, Allen, Kyle M., Gàlvez, Maria E., Michalsky, Ronald, Steinfeld, Aldo

“…Separation and concentration of O2 from gas mixtures is central to several sustainable energy technologies, such as solar‐driven synthesis of liquid…”
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Crisis regulations: The unexpected consequences of floating NAV for money market funds by Allen, Kyle D., Winters, Drew B.

“…From the inception of money market funds (MMFs), all MMFs reported a fixed $1 NAV (Net Asset Value). In July 2014, the Securities and Exchange Commission (SEC)…”
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Application of magnetic particle imaging to evaluate nanoparticle fate in rodent joints by Ajayi, Tolulope O., Liu, Sitong, Rosen, Chelsea, Rinaldi-Ramos, Carlos M., Allen, Kyle D., Sharma, Blanka

“…Nanoparticles are a promising approach for improving intra-articular drug delivery and tissue targeting. However, techniques to non-invasively track and…”
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Wheel Running Exacerbates Joint Damage after Meniscal Injury in Mice, but Does Not Alter Gait or Physical Activity Levels by Chan, Kiara M., Griffith, Jacob L., Pacheco, Yan Carlos, Allen, Kyle D.

“…Exercise and physical activity are recommended to reduce pain and improve joint function in patients with knee osteoarthritis (OA). However, exercise has dose…”
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A Novel Device for the Quantification of Synovial Fluid Viscosity Via Magnetic Deflection by Armington, Samuel L, Shah, Yash Y, Dobson, Jon, Allen, Kyle D

“…Changes in synovial fluid viscosity may be used to detect joint disease; however, methods to evaluate these changes at the point-of-care are currently…”
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Intra-articular delivery of an indoleamine 2,3-dioxygenase galectin-3 fusion protein for osteoarthritis treatment in male Lewis rats by Partain, Brittany D, Bracho-Sanchez, Evelyn, Farhadi, Shaheen A, Yarmola, Elena G, Keselowsky, Benjamin G, Hudalla, Gregory A, Allen, Kyle D

“…Osteoarthritis (OA) is driven by low-grade inflammation, and controlling local inflammation may offer symptomatic relief. Here, we developed an indoleamine…”
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Quadrupedal rodent gait compensations in a low dose monoiodoacetate model of osteoarthritis by Lakes, Emily H., Allen, Kyle D.

“…•Examined rat quadrupedal gait after intra-articular injection of saline or 1 mg MIA.•1 mg MIA resulted in minor joint degeneration and a shuffle-step…”
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Gait Analysis Methods for Rodent Models of Osteoarthritis by Jacobs, Brittany Y., Kloefkorn, Heidi E., Allen, Kyle D.

“…Patients with osteoarthritis (OA) primarily seek treatment due to pain and disability, yet the primary endpoints for rodent OA models tend to be histological…”
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The response of money market fund investors and managers to government shutdowns by Allen, Kyle D., Baig, Ahmed, Winters, Drew B.

“…We examine whether impending government shutdowns affect money market fund (MMF) investors and managers. Research suggests that market participants place…”
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Autonomic Nervous System Dysregulation and Osteoarthritis Pain: Mechanisms, Measurement, and Future Outlook by Yeater, Taylor D., Cruz, Carlos J., Cruz-Almeida, Yenisel, Allen, Kyle D.

“…Purpose of Review The autonomic nervous system is an important regulator of stress responses and exhibits functional changes in chronic pain states. This…”
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Factors affecting the reliability of behavioral assessments for rodent osteoarthritis models by Jacobs, Brittany Y, Allen, Kyle D

“…The translational value of osteoarthritis (OA) models is often debated because numerous studies have shown that animal models frequently fail to predict the…”
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Characterization of Post‐Traumatic Osteoarthritis in Rats Following Anterior Cruciate Ligament Rupture by Non‐Invasive Knee Injury (NIKI) by Brown, Shannon B., Hornyak, Jessica A., Jungels, Ryan R., Shah, Yash Y., Yarmola, Elena G., Allen, Kyle D., Sharma, Blanka

“…ABSTRACT Small animal models are essential for studying anterior cruciate ligament (ACL) injury, one of the leading risk factors for post‐traumatic…”
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Spatiotemporal gait compensations following medial collateral ligament and medial meniscus injury in the rat: correlating gait patterns to joint damage by Kloefkorn, Heidi E, Jacobs, Brittany Y, Loye, Ayomiposi M, Allen, Kyle D

“…After transection of the medial collateral ligament and medial meniscus (MCLT + MMT) in the rat, focal cartilage lesions develop over 4-6 weeks; however, sham…”
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The response of money market funds to the COVID-19 pandemic by Allen, Kyle D., Baig, Ahmed, Winters, Drew B.

“…•The Covid-19 Pandemic has increased the attention paid to money market funds.•Using Covid Intensity measures we analyze how MMF mangers and investors…”
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Neuromodulation as a Potential Disease-Modifying Therapy for Osteoarthritis by Cruz, Carlos J., Dewberry, L. Savannah, Otto, Kevin J., Allen, Kyle D.

“…Purpose of Review The following review discusses the therapeutic potential of targeting the autonomic nervous system (ANS) for osteoarthritis (OA) treatment…”
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