Search Results - "Allen, Karen O"

Safety and Immunogenicity of a DNA Vaccine Encoding Carcinoembryonic Antigen and Hepatitis B Surface Antigen in Colorectal Carcinoma Patients by CONRY, Robert M, CURIEL, David T, STRONG, Theresa V, MOORE, Susan E, ALLEN, Karen O, BARLOW, Daunte L, SHAW, Denise R, LOBUGLIO, Albert F

“…Despite an abundance of preclinical data, relatively little is known regarding the efficacy of DNA vaccination in humans. Here, we present results from a…”
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Phase I Study of the Intratumoral Administration of Recombinant Canarypox Viruses Expressing B7.1 and Interleukin 12 in Patients with Metastatic Melanoma by TRIOZZI, Pierre L, ALLEN, Karen O, CARLISLE, Ronda R, CRAIG, Mark, LOBUGLIO, Albert F, CONRY, Robert M

“…The objective of this study was to evaluate the safety and activity of the intratumoral administration of the immune costimulatory molecule, B7.1, encoded by a…”
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Immunization of colorectal cancer patients with recombinant baculovirus-derived KSA (Ep-CAM) formulated with monophosphoryl lipid A in liposomal emulsion, with and without granulocyte-macrophage colony-stimulating factor by Neidhart, Jeffrey, Allen, Karen O., Barlow, Daunte L., Carpenter, Mark, Shaw, Denise R., Triozzi, Pierre L., Conry, Robert M.

“…KSA (Ep-CAM) is highly expressed by colorectal cancers. The safety and immunologic effects of a vaccine consisting of recombinant baculovirus-derived KSA…”
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Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse by TRIOZZI, Pierre L, ALDRICH, Wayne, ALLEN, Karen O, CARLISLE, Ronda R, LOBUGLIO, Albert F, CONRY, Robert M

“…Immunization with plasmid DNA represents an attractive method for increasing cellular immune responses against cancer antigens. The safety and immunologic…”
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Intratumoral administration of a recombinant canarypox virus expressing interleukin 12 in patients with metastatic melanoma by Triozzi, Pierre L, Strong, Theresa V, Bucy, R Pat, Allen, Karen O, Carlisle, Ronda R, Moore, Susan E, Lobuglio, Albert F, Conry, Robert M

“…The aim of this study was to evaluate the tolerability and activity of intratumoral administered human interleukin 12 encoded by a vector derived from the…”
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Human Autoantibodies to Carcinoembryonic Antigen (CEA) Induced by a Vaccinia-CEA Vaccine by CONRY, R. M, ALLEN, K. O, LEE, S.-W, MOORE, S. E, SHAW, D. R, LOBUGLIO, A. F

“…Carcinoembryonic antigen (CEA) is a well-characterized oncofetal glycoprotein whose overexpression by human adenocarcinomas has been a target for cancer…”
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Phase I Trial of a Recombinant Vaccinia Virus Encoding Carcinoembryonic Antigen in Metastatic Adenocarcinoma: Comparison of Intradermal versus Subcutaneous Administration by CONRY, R. M, KHAZAELI, M. B, SALEH, M. N, ALLEN, K. O, BARLOW, D. L, MOORE, S. E, CRAIG, D, ARANI, R. B, SCHLOM, J, LOBUGLIO, A. F

“…The principal objectives of this trial were twofold: ( a ) to examine the safety and relative efficacy of intradermal needle injection versus s.c. jet…”
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Antitumor activity of the intratumoral injection of fowlpox vectors expressing a triad of costimulatory molecules and granulocyte/macrophage colony stimulating factor in mesothelioma by Triozzi, Pierre L., Aldrich, Wayne, Allen, Karen O., Lima, Jose, Shaw, Denise R., Strong, Theresa V.

“…Deficiency in costimulatory molecule expression has been implicated in the ability of tumors to escape immune effectors. The activity of the intratumoral…”
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Effect of docetaxel chemotherapy on the activity of a gonadotropin releasing hormone vaccine in patients with advanced prostate cancer by Triozzi, Pierre L., Bolger, Graeme B., Neidhart, Jeffrey, Rinehart, John J., Saleh, Mansoor, Allen, Karen O., Sellers, Sandra, Waddell, Mary J.

“…BACKGROUND Gonadotropin releasing hormone (GnRH)‐DT vaccine elicits antibody that may inhibit prostate cancers indirectly by blocking GnRH induced gonadotropin…”
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Quality assurance for investigator-initiated trials by Allen, Karen O., El Shayeb, Mohamed, Saleh, Mansoor N., Fiveash, John B.

“…Abstract only…”
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Polynucleotide immunization of nonhuman primates against carcinoembryonic antigen by CONRY, R. M, WHITE, S. A, CURIEL, D. T, LOBUGLIO, A. F, FULTZ, P. N, KHAZAELI, M. B, STRONG, T. V, ALLEN, K. O, BARLOW, D. L, MOORE, S. E, COAN, P. N, DAVIS, I

“…In preparation for a Phase I trial of DNA immunization against carcinoembryonic antigen (CEA) in patients with colorectal carcinoma, we have produced a single…”
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Effects of a novel purine nucleoside phosphorylase inhibitor, BCX-34, on activation and proliferation of normal human lymphoid cells by Conry, Robert M., Bantia, Shanta, Turner, Heather S., Barlow, Daunte L., Allen, Karen O., LoBuglio, Albert F., Montgomery, John A., Walsh, Gerald M.

“…The antiproliferative effect of BCX-34 was tested in normal human peripheral blood mononuclear cells (PBMCs) induced to proliferate with OKT3, tetanus toxoid,…”
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