Search Results - "Allen, Josiah D"

CYP2D6 Genetic Polymorphisms and Risperidone Pharmacokinetics: A Systematic Review and Meta‐analysis by Zhang, Lusi, Brown, Sarah Jane, Shan, Yuting, Lee, Adam M., Allen, Josiah D., Eum, Seenae, Leon, Jose, Bishop, Jeffrey R.

“…Background Risperidone is a second‐generation antipsychotic drug metabolized to an active metabolite, 9‐hydroxyrisperidone, primarily by cytochrome P450 (CYP)…”
Get full text

Assessing pharmacogenomic literacy in China through validation of the Chinese version of the Minnesota Assessment of Pharmacogenomic Literacy by Zhang, Lusi, Zhou, Shuqin, Allen, Josiah D, Wang, Fan, Pittenger, Amy L, Bishop, Jeffrey R

“…Pharmacogenomics (PGx) implementation into clinical care is rapidly increasing in China. However, the extent to which the public understands PGx testing and…”
Get full text

Real‐world implementation of DPYD and UGT1A1 pharmacogenetic testing in a community‐based cancer center by Muldoon, Megan, Beck, Mollie, Sebree, Nichlas, Yoder, Robin, Ritter, Stacey, Allen, Josiah D., Alqahtani, Zuhair, Grund, Jaime, Philips, Brooke, Hesse, Kristina, El Rouby, Nihal

“…We set out to demonstrate the feasibility of pharmacogenetic testing of DPYD and UGT1A1 and explore the clinical benefits in a community‐based cancer center…”
Get full text

Reply to “A call for reporting of tumor‐specific outcomes in studies of DPYD genotyping” by El Rouby, Nihal, Allen, Josiah D., Muldoon, Megan, Beck, Mollie, Hesse, Kristina, Sebree, Nichlas, Yoder, Robin, Ritter, Stacey, Alqahtani, Zuhair, Grund, Jaime, Holbrook, Brooke Philips

Get full text

Editorial: Precision psychiatry from a pharmacogenetics perspective by Brown, Lisa C, Allen, Josiah D, Eyre, Harris A, Baune, Bernhard T, Aitchison, Katherine J, Bousman, Chad A

Get full text

Development and Implementation of In-House Pharmacogenomic Testing Program at a Major Academic Health System by Mroz, Pawel, Michel, Stephen, Allen, Josiah D., Meyer, Tim, McGonagle, Erin J., Carpentier, Rachel, Vecchia, Alexandra, Schlichte, Allyson, Bishop, Jeffrey R., Dunnenberger, Henry M., Yohe, Sophia, Thyagarajan, Bharat, Jacobson, Pamala A., Johnson, Steven G.

“…Pharmacogenomics (PGx) studies how a person’s genes affect the response to medications and is quickly becoming a significant part of precision medicine. The…”
Get full text

Intersection and Considerations for Patient-Centered Care, Patient Experience, and Medication Experience in Pharmacogenomics by Murry, Logan T, Hillman, Lisa A, Allen, Josiah D, Bishop, Jeffrey R

“…As healthcare continues to embrace the concept of person- and patient-centered care, pharmacogenomics, patient experience, and medication experience will…”
Get full text

A systematic review of genome-wide association studies of antipsychotic response by Allen, Josiah D, Bishop, Jeffrey R

“…Clinical symptom response to antipsychotic medications is highly variable. Genome-wide association studies (GWAS) provide a 'hypothesis-free' method of…”
Get full text

Utility of integrated pharmacogenomic testing to support the treatment of major depressive disorder in a psychiatric outpatient setting by Hall-Flavin, Daniel K., Winner, Joel G., Allen, Josiah D., Carhart, Joseph M., Proctor, Brian, Snyder, Karen A., Drews, Maureen S., Eisterhold, Linda L., Geske, Jennifer, Mrazek, David A.

“…OBJECTIVEThe objective was to evaluate the potential benefit of an integrated, five-gene pharmacogenomic test and interpretive report (GeneSight) for the…”
Get full text

A prospective, randomized, double-blind study assessing the clinical impact of integrated pharmacogenomic testing for major depressive disorder by Winner, Joel G, Carhart, Joseph M, Altar, C Anthony, Allen, Josiah D, Dechairo, Bryan M

“…A prospective double-blind randomized control trial (RCT) to evaluate the benefit of a combinatorial, five gene pharmacogenomic test and interpretive report…”
Get more information

Combinatorial pharmacogenomic guidance for psychiatric medications reduces overall pharmacy costs in a 1 year prospective evaluation by Winner, Joel G., Carhart, Joseph M., Altar, C. Anthony, Goldfarb, Seth, Allen, Josiah D., Lavezzari, Gabriela, Parsons, Kelly K., Marshak, Andrew G., Garavaglia, Susan, Dechairo, Bryan M.

“…The objective of this project was to determine pharmacy cost savings and improvement in adherence based on a combinatorial pharmacogenomic test (CPGx ) in…”
Get full text

A Scoping Review of Attitudes and Experiences with Pharmacogenomic Testing among Patients and the General Public: Implications for Patient Counseling by Allen, Josiah D, Pittenger, Amy L, Bishop, Jeffrey R

“…The use of pharmacogenomic (PGx) tests is increasing, but there are not standard approaches to counseling patients on their implications or results. To inform…”
Get full text

Pharmacogenomics education, research and clinical implementation in the state of Minnesota by Bishop, Jeffrey R, Huang, R Stephanie, Brown, Jacob T, Mroz, Pawel, Johnson, Steven G, Allen, Josiah D, Bielinski, Suzette J, England, Julie, Farley, Joel F, Gregornik, David, Giri, Jyothsna, Kroger, Christine, Long, Susie E, Luczak, Tiana, McGonagle, Erin J, Ma, Sisi, Matey, Eric T, Mandic, Pinar K, Moyer, Ann M, Nicholson, Wayne T, Petry, Natasha, Pawloski, Pamala A, Schlichte, Allyson, Schondelmeyer, Stephen W, Seifert, Randall D, Speedie, Marilyn K, Stenehjem, David, Straka, Robert J, Wachtl, Jason, Waring, Stephen C, Ness, Brian Van, Zierhut, Heather A, Aliferis, Constantin, Wolf, Susan M, McCarty, Catherine A, Jacobson, Pamala A

“…Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increase drug safety and effectiveness…”
Get full text

Development and Validation of the Minnesota Assessment of Pharmacogenomic Literacy (MAPL) by Allen, Josiah D, Zhang, Lusi, Johnson, Alyssa N K, Jacobson, Pamala A, McCarty, Catherine A, Pittenger, Amy L, Bishop, Jeffrey R

“…Ensuring that patients have an adequate understanding of pharmacogenomic (PGx) test results is a critical component of implementing precision medicine into…”
Get full text

Patients and clinicians report higher-than-average satisfaction with psychiatric genotyping for depressed inpatients by Kung, Simon, Allen, Josiah D

Get full text

The clinical validity and utility of combinatorial pharmacogenomics: Enhancing patient outcomes by Benitez, Joachim, Jablonski, Michael R., Allen, Josiah D., Winner, Joel G.

“…Prescribing safe and effective medications is a challenge in psychiatry. While clinical use of pharmacogenomic testing for individual genes has provided some…”
Get full text

Population-based prevalence of smoking in psychiatric inpatients: a focus on acute suicide risk and major diagnostic groups by Lineberry, Timothy W, Allen, Josiah D, Nash, Jessica, Galardy, Christine W

“…Abstract Objective The aim of the study was to define the extent of current and lifetime smoking by diagnostic groups and suicide risk as reason for admission…”
Get full text

Clinical Utility of Combinatorial Pharmacogenomics-Guided Antidepressant Therapy: Evidence from Three Clinical Studies by Altar, C Anthony, Carhart, Joseph, Allen, Josiah D, Hall-Flavin, Daniel, Winner, Joel, Dechairo, Bryan

“…DNA of 258 patients with treatment-resistant depression was collected in three 8-10 week, two-arm, prospective clinical trials. Forty-four allelic variations…”
Get full text

The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation by Cavallari, Larisa H, Hicks, J Kevin, Patel, Jai N, Elchynski, Amanda L, Smith, D Max, Bargal, Salma A, Fleck, Ashley, Aquilante, Christina L, Killam, Shayna R, Lemke, Lauren, Ochi, Taichi, Ramsey, Laura B, Haidar, Cyrine E, Ho, Teresa, El Rouby, Nihal, Monte, Andrew A, Allen, Josiah D, Beitelshees, Amber L, Bishop, Jeffrey R, Bousman, Chad, Campbell, Ronald, Cicali, Emily J, Cook, Kelsey J, Duong, Benjamin, Tsermpini, Evangelia Eirini, Girdwood, Sonya Tang, Gregornik, David B, Grimsrud, Kristin N, Lamb, Nathan, Lee, James C, Lopez, Rocio Ortiz, Mazhindu, Tinashe Adrian, Morris, Sarah A, Nagy, Mohamed, Nguyen, Jenny, Pasternak, Amy L, Petry, Natasha, van Schaik, Ron H N, Schultz, April, Skaar, Todd C, Al Alshaykh, Hana, Stevenson, James M, Stone, Rachael M, Tran, Nam K, Tuteja, Sony, Woodahl, Erica L, Yuan, Li-Chi, Lee, Craig R

“…Pharmacogenetics promises to optimize treatment-related outcomes by informing optimal drug selection and dosing based on an individual's genotype in…”
Get full text