Search Results - "Allen, J. H."

Optical manipulation of nanoparticles and biomolecules in sub-wavelength slot waveguides by Moore, Sean D, Erickson, David, Klug, Matthew, Schmidt, Bradley S, Lipson, Michal, Yang, Allen H. J

“…The ability to manipulate nanoscopic matter precisely is critical for the development of active nanosystems. Optical tweezers are excellent tools for…”
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Acoustophoretic Sorting of Viable Mammalian Cells in a Microfluidic Device by Yang, Allen H. J, Soh, H. Tom

“…We report the first use of ultrasonic acoustophoresis for the label-free separation of viable and nonviable mammalian cells within a microfluidic device. Cells…”
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Forces and Transport Velocities for a Particle in a Slot Waveguide by Yang, Allen H. J, Lerdsuchatawanich, Tadsanapan, Erickson, David

“…Optofluidic transport seeks to exploit the high-intensity electromagnetic energy in waveguiding structures to manipulate nanoscopic matter using radiation…”
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Nanobiosensors: optofluidic, electrical and mechanical approaches to biomolecular detection at the nanoscale by Erickson, David, Mandal, Sudeep, Yang, Allen H. J., Cordovez, Bernardo

“…Next generation biosensor platforms will require significant improvements in sensitivity, specificity and parallelity in order to meet the future needs of a…”
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Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse by Allen, J H, de Moore, G M, Heddle, R, Twartz, J C

“…Background and aims: To explore the association between chronic cannabis abuse and a cyclical vomiting illness that presented in a series of cases in South…”
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Comparative Molecular Characterization and Pharmacokinetics of IgG1-Fc and Engineered Fc Human Antibody Variants to Insulin-like Growth Factor 2 Receptor (IGF2R) by Prabaharan, Chandra B, Giri, Sabeena, Allen, Kevin J H, Bato, Katrina E M, Mercado, Therese R, Malo, Mackenzie E, Carvalho, Jorge L C, Dadachova, Ekaterina, Uppalapati, Maruti

“…Novel therapeutic approaches are much needed for the treatment of osteosarcoma. Targeted radionuclide therapy (TRT) and radioimmunotherapy (RIT) are promising…”
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Radioimmunotherapy of methicillin-resistant Staphylococcus aureus in planktonic state and biofilms by van Dijk, B, Allen, K J H, Helal, M, Vogely, H C, Lam, M G E H, de Klerk, J M H, Weinans, H, van der Wal, B C H, Dadachova, E

“…Implant associated infections such as periprosthetic joint infections are difficult to treat as the bacteria form a biofilm on the prosthetic material. This…”
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Image-Based Dosimetry in Dogs and Cross-Reactivity with Human Tissues of IGF2R-Targeting Human Antibody by Allen, Kevin J H, Kwon, Ohyun, Hutcheson, Matthew R, Grudzinski, Joseph J, Cain, Stuart M, Cruz, Frederic A, Vinayakamoorthy, Remitha M, Sun, Ying S, Fairley, Lindsay, Prabaharan, Chandra B, Dickinson, Ryan, MacDonald-Dickinson, Valerie, Uppalapati, Maruti, Bednarz, Bryan P, Dadachova, Ekaterina

“…Osteosarcoma (OS) represents the most common primary bone tumor in humans and in companion dogs, being practically phenotypically identical. There is a need…”
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Targeting Melanin in Melanoma with Radionuclide Therapy by Allen, Kevin J. H., Malo, Mackenzie E., Jiao, Rubin, Dadachova, Ekaterina

“…Nearly 100,000 individuals are expected to be diagnosed with melanoma in the United States in 2022. Treatment options for late-stage metastatic disease up…”
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In Vitro and In Vivo Characterization of 89Zirconium-Labeled Lintuzumab Molecule by Allen, Kevin J. H., Jiao, Rubin, Li, Jason, Beckford-Vera, Denis R., Dadachova, Ekaterina

“…Objective: Positron emission tomography (PET) imaging is a powerful non-invasive method to determine the in vivo behavior of biomolecules. Determining…”
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Mechanistic Insights into Synergy between Melanin-Targeting Radioimmunotherapy and Immunotherapy in Experimental Melanoma by Malo, Mackenzie E, Allen, Kevin J H, Jiao, Rubin, Frank, Connor, Rickles, David, Dadachova, Ekaterina

“…Melanoma incidence continues to rise, and while therapeutic approaches for early stage cases are effective, metastatic melanoma continues to be associated with…”
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Accurate Zygote-Specific Discrimination of Single-Nucleotide Polymorphisms Using Microfluidic Electrochemical DNA Melting Curves by Yang, Allen H. J., Hsieh, Kuangwen, Patterson, Adriana S., Ferguson, B. Scott, Eisenstein, Michael, Plaxco, Kevin W., Soh, H. Tom

“…We report the first electrochemical system for the detection of single‐nucleotide polymorphisms (SNPs) that can accurately discriminate homozygous and…”
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The Bifunctional Dimer Caffeine-Indan Attenuates α-Synuclein Misfolding, Neurodegeneration and Behavioral Deficits after Chronic Stimulation of Adenosine A1 Receptors by Jakova, Elisabet, Aigbogun, Omozojie P, Moutaoufik, Mohamed Taha, Allen, Kevin J H, Munir, Omer, Brown, Devin, Taghibiglou, Changiz, Babu, Mohan, Phenix, Chris P, Krol, Ed S, Cayabyab, Francisco S

“…We previously found that chronic adenosine A1 receptor stimulation with N -Cyclopentyladenosine increased α-synuclein misfolding and neurodegeneration in a…”
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Safety Evaluation of an Alpha-Emitter Bismuth-213 Labeled Antibody to (1→3)-β-Glucan in Healthy Dogs as a Prelude for a Trial in Companion Dogs with Invasive Fungal Infections by Helal, Muath, Allen, Kevin J H, Burgess, Hilary, Jiao, Rubin, Malo, Mackenzie E, Hutcheson, Matthew, Dadachova, Ekaterina, Snead, Elisabeth

“…: With the limited options available for therapy to treat invasive fungal infections (IFI), radioimmunotherapy (RIT) can potentially offer an effective…”
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225Ac‐labeled CD33‐targeting antibody reverses resistance to Bcl‐2 inhibitor venetoclax in acute myeloid leukemia models by Garg, Ravendra, Allen, Kevin J. H., Dawicki, Wojciech, Geoghegan, Eileen M., Ludwig, Dale L., Dadachova, Ekaterina

“…ABSTRACT Purpose Despite the availability of new drugs, many patients with acute myeloid leukemia (AML) do not achieve remission and outcomes remain poor…”
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Radioimmunotherapy Targeting IGF2R on Canine-Patient-Derived Osteosarcoma Tumors in Mice and Radiation Dosimetry in Canine and Pediatric Models by Broqueza, Jaline, Prabaharan, Chandra B, Allen, Kevin J H, Jiao, Rubin, Fisher, Darrell R, Dickinson, Ryan, MacDonald-Dickinson, Valerie, Uppalapati, Maruti, Dadachova, Ekaterina

“…Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant improvements in the last two decades, and novel effective treatments are…”
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Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody by Helal, Muath, Allen, Kevin J H, van Dijk, Bruce, Nosanchuk, Joshua D, Snead, Elisabeth, Dadachova, Ekaterina

“…Invasive fungal infections (IFI) cause devastating morbidity and mortality, with the number of IFIs more than tripling since 1979. Our laboratories were the…”
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Comparative Radioimmunotherapy of Experimental Melanoma with Novel Humanized Antibody to Melanin Labeled with 213Bismuth and 177Lutetium by Allen, Kevin J H, Jiao, Rubin, Malo, Mackenzie E, Frank, Connor, Fisher, Darrell R, Rickles, David, Dadachova, Ekaterina

“…Melanoma is a cancer with increasing incidence and there is a need for alternatives to immunotherapy within effective approaches to treatment of metastatic…”
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Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics by Allen, Kevin J H, Jiao, Rubin, Malo, Mackenzie E, Frank, Connor, Dadachova, Ekaterina

“…(1) Background: Monoclonal antibodies are used in the treatment of multiple conditions including cancer, autoimmune disorders, and infectious diseases. One of…”
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Gel-based optical waveguides with live cell encapsulation and integrated microfluidics by Jain, Aadhar, Yang, Allen H J, Erickson, David

“…In this Letter, we demonstrate a biocompatible microscale optical device fabricated from agarose hydrogel that allows for encapsulation of cells inside an…”
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