Search Results - "Allegrini, G"

Prognostic and predictive role of neutrophil/lymphocytes ratio in metastatic colorectal cancer: a retrospective analysis of the TRIBE study by GONO by Dell’Aquila, E., Cremolini, C., Zeppola, T., Lonardi, S., Bergamo, F., Masi, G., Stellato, M., Marmorino, F., Schirripa, M., Urbano, F., Ronzoni, M., Tomasello, G., Zaniboni, A., Racca, P., Buonadonna, A., Allegrini, G., Fea, E., Di Donato, S., Chiara, S., Tonini, G., Tomcikova, D., Boni, L., Falcone, A., Santini, D.

“…Neutrophil/lymphocyte ratio (NLR), defined as absolute neutrophils count divided by absolute lymphocytes count, has been reported as poor prognostic factor in…”
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Genomic prediction of cognitive traits in childhood and adolescence by Allegrini, A. G., Selzam, S., Rimfeld, K., von Stumm, S., Pingault, J. B., Plomin, R.

“…Recent advances in genomics are producing powerful DNA predictors of complex traits, especially cognitive abilities. Here, we leveraged summary statistics from…”
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Continuation or reintroduction of bevacizumab beyond progression to first-line therapy in metastatic colorectal cancer: final results of the randomized BEBYP trial by Masi, G., Salvatore, L., Boni, L., Loupakis, F., Cremolini, C., Fornaro, L., Schirripa, M., Cupini, S., Barbara, C., Safina, V., Granetto, C., Fea, E., Antonuzzo, L., Boni, C., Allegrini, G., Chiara, S., Amoroso, D., Bonetti, A., Falcone, A.

“…The BEBYP trial is a prospective, randomized, open-label, multicenter, phase III study evaluating the continuation or reintroduction of bevacizumab with…”
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Multivariable G-E interplay in the prediction of educational achievement by Allegrini, Andrea G, Karhunen, Ville, Coleman, Jonathan R I, Selzam, Saskia, Rimfeld, Kaili, von Stumm, Sophie, Pingault, Jean-Baptiste, Plomin, Robert

“…Polygenic scores are increasingly powerful predictors of educational achievement. It is unclear, however, how sets of polygenic scores, which partly capture…”
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Primary tumor sidedness and benefit from FOLFOXIRI plus bevacizumab as initial therapy for metastatic colorectal cancer. Retrospective analysis of the TRIBE trial by GONO by Cremolini, C., Antoniotti, C., Lonardi, S., Bergamo, F., Cortesi, E., Tomasello, G., Moretto, R., Ronzoni, M., Racca, P., Loupakis, F., Zaniboni, A., Tonini, G., Buonadonna, A., Marmorino, F., Allegrini, G., Granetto, C., Masi, G., Zagonel, V., Sensi, E., Fontanini, G., Boni, L., Falcone, A.

“…Right-sided metastatic colorectal cancer (mCRC) patients have poor prognosis and achieve limited benefit from first-line doublets plus a targeted agent. In…”
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Impact of age and gender on the safety and efficacy of chemotherapy plus bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by Marmorino, F., Rossini, D., Lonardi, S., Moretto, R., Zucchelli, G., Aprile, G., Dell’Aquila, E., Ratti, M., Bergamo, F., Masi, G., Urbano, F., Ronzoni, M., Libertini, M., Borelli, B., Randon, G., Buonadonna, A., Allegrini, G., Pella, N., Ricci, V., Boccaccino, A., Latiano, T.P., Cordio, S., Passardi, A., Tamburini, E., Boni, L., Falcone, A., Cremolini, C.

“…The phase III TRIBE and TRIBE2 studies randomized metastatic colorectal cancer patients to first-line FOLFOXIRI/bevacizumab or a doublet (FOLFIRI or…”
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FOLFOXIRI or FOLFOXIRI plus bevacizumab as first-line treatment of metastatic colorectal cancer: a propensity score-adjusted analysis from two randomized clinical trials by Cremolini, C., Loupakis, F., Masi, G., Lonardi, S., Granetto, C., Mancini, M.L., Chiara, S., Moretto, R., Rossini, D., Vitello, S., Allegrini, G., Tonini, G., Bergamo, F., Tomasello, G., Ronzoni, M., Buonadonna, A., Bustreo, S., Barbara, C., Boni, L., Falcone, A.

“…FOLFOXIRI plus bevacizumab is a valid option as upfront treatment for metastatic colorectal cancer (mCRC) patients. While several trials investigated the…”
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Do children with ADHD symptoms become socially isolated? Longitudinal within-person associations in a nationally-representative cohort by Thompson, K. N., Agnew-Blais, J. C., Allegrini, A. G., Bryan, B. T., Danese, A., Odgers, C. L., Matthews, T., Arseneault, L.

“…IntroductionSocial isolation in childhood can be detrimental to physical and mental health. Children with neurodevelopmental disorders, such as attention…”
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Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits by Akingbuwa, Wonuola A., Hammerschlag, Anke R., Allegrini, Andrea G., Sallis, Hannah, Kuja‐Halkola, Ralf, Rimfeld, Kaili, Lichtenstein, Paul, Lundstrom, Sebastian, Munafò, Marcus R., Plomin, Robert, Nivard, Michel G., Bartels, Meike, Middeldorp, Christel M.

“…Ubiquitous associations have been detected between different types of childhood psychopathology and polygenic risk scores based on adult psychiatric disorders…”
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Genetic and phenotypic heterogeneity in early neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study by Hegemann, Laura, Corfield, Elizabeth C, Askelund, Adrian Dahl, Allegrini, Andrea G, Askeland, Ragna Bugge, Ronald, Angelica, Ask, Helga, St Pourcain, Beate, Andreassen, Ole A, Hannigan, Laurie J, Havdahl, Alexandra

“…Autism and different neurodevelopmental conditions frequently co-occur, as do their symptoms at sub-diagnostic threshold levels. Overlapping traits and shared…”
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Randomized Trial of Two Induction Chemotherapy Regimens in Metastatic Colorectal Cancer: An Updated Analysis by MASI, Gianluca, VASILE, Enrico, FABBRI, Maria Agnese, PUGLISI, Martina, TRENTA, Patrizia, GRANETTO, Cristina, CHIARA, Silvana, FIORETTO, Luisa, ALLEGRINI, Giacomo, CRINO, Lucio, ANDREUCCETTI, Michele, FALCONE, Alfredo, LOUPAKIS, Fotios, CUPINI, Samanta, FORNARO, Lorenzo, BALDI, Giacomo, SALVATORE, Lisa, CREMOLINI, Chiara, STASI, Irene, BRUNETTI, Isa

“…In a randomized trial with a median follow-up of 18.4 months, 6 months of induction chemotherapy with a three-drug regimen comprising 5-fluorouracil (by…”
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A meta-analysis of genetic effects associated with neurodevelopmental disorders and co-occurring conditions by Gidziela, Agnieszka, Ahmadzadeh, Yasmin I., Michelini, Giorgia, Allegrini, Andrea G., Agnew-Blais, Jessica, Lau, Lok Yan, Duret, Megan, Procopio, Francesca, Daly, Emily, Ronald, Angelica, Rimfeld, Kaili, Malanchini, Margherita

“…A systematic understanding of the aetiology of neurodevelopmental disorders (NDDs) and their co-occurrence with other conditions during childhood and…”
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Comparing findings from the random‐intercept cross‐lagged panel model and the monozygotic twin difference cross‐lagged panel model: Maladaptive parenting and offspring emotional and behavioural problems by Kullberg, Marie‐Louise J., Van Schie, Charlotte C., Allegrini, Andrea G., Ahmadzadeh, Yasmin, Wechsler, Daniel L., Elzinga, Bernet M., McAdams, Tom A.

“…Background In this study we compare results obtained when applying the monozygotic twin difference cross‐lagged panel model (MZD‐CLPM) and a random intercept…”
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Developmental co‐occurrence of psychopathology dimensions in childhood by Allegrini, Andrea G., Beijsterveldt, Toos, Boomsma, Dorret I., Rimfeld, Kaili, Pingault, Jean‐Baptiste, Plomin, Robert, Bartels, Meike, Nivard, Michel G.

“…Background Comorbidity between psychopathologies may be attributed to genetic and environmental differences between people as well as causal processes within…”
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Impact of age and gender on safety and efficacy of first-line FOLFOXIRI/bevacizumab in mCRC: a pooled analysis of TRIBE and TRIBE2 studies by Zucchelli, G., Marmorino, F., Rossini, D., Aprile, G., Casagrande, M., Lonardi, S., Murgioni, S., Dell’Aquila, E., Tomasello, G., Moretto, R., Antoniotti, C., Borelli, B., Urbano, F., Ronzoni, M., Zaniboni, A., Manglaviti, S., Buonadonna, A., Ritorto, G., Masi, G., Allegrini, G., Falcone, A., Cremolini, C.

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Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib by Bocci, G, Falcone, A, Fioravanti, A, Orlandi, P, Di Paolo, A, Fanelli, G, Viacava, P, Naccarato, A G, Kerbel, R S, Danesi, R, Del Tacca, M, Allegrini, G

“…Metronomic chemotherapy refers to the administration of chemotherapy at low, nontoxic doses on a frequent schedule with no prolonged breaks. The aim of the…”
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Cardiac safety of adjuvant non-pegylated liposomal doxorubicin combined with cyclophosphamide and followed by paclitaxel in older breast cancer patients by Coltelli, L, Cappelli, S, Fontana, A, Lucchesi, S, Bocci, G, Farnesi, A, Arrighi, G, Finale, C, Salvadori, B, De Angelis, C, Ginocchi, L, Falcone, A, Fabiani, I, Allegrini, G

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The winding roads to adulthood: A twin study by Rimfeld, Kaili, Malanchini, Margherita, Packer, Amy E., Gidziela, Agnieszka, Allegrini, Andrea G., Ayorech, Ziada, Smith‐Woolley, Emily, McMillan, Andrew, Ogden, Rachel, Dale, Philip S., Eley, Thalia C., Plomin, Robert

“…Aims Here we report the results of the first systematic investigation of genetic and environmental influences on 57 psychological traits covering major issues…”
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A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients by Allegrini, G, Falcone, A, Fioravanti, A, Barletta, M T, Orlandi, P, Loupakis, F, Cerri, E, Masi, G, Di Paolo, A, Kerbel, R S, Danesi, R, Del Tacca, M, Bocci, G

“…The pharmacokinetics (PK) and pharmacodynamics (PD) of metronomic irinotecan have not been studied in cancer patients. The aim of the study is to investigate…”
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Development of a new clinical nomogram including velocity rate of disease progression to predict outcome in metastatic colorectal cancer patients treated with bevacizumab beyond progression: A subanalysis from tribe trial by Dell'Aquila, E., Pantano, F., Rossini, D., Stellato, M., Lonardi, S., Masi, G., Schirripa, M., Marmorino, F., Antoniotti, C., Murgioni, S., Tomasello, G., Ronzoni, M., Racca, P., Vincenzi, B., Allegrini, G., Urbano, F., Buonadonna, A., Banzi, M., Tonini, G., Cremolini, C., Falcone, A., Santini, D.

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