Search Results - "Allegretti, M"

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice by Zarbock, A, Allegretti, M, Ley, K

“…Background and purpose: Acute lung injury (ALI) remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key…”
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Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical disease Schistosomiasis mansoni by de Moraes, Josué, de Oliveira, Rosimeire N, Costa, Jéssica P, Junior, Antonio L G, de Sousa, Damião P, Freitas, Rivelilson M, Allegretti, Silmara M, Pinto, Pedro L S

“…Schistosomiasis is a major endemic disease that affects hundreds of millions worldwide. Since the treatment and control of this parasitic disease rely on a…”
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Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy by Cristiano, C., Giorgio, C., Cocchiaro, P., Boccella, S., Cesta, M.C., Castelli, V., Liguori, F.M., Cuozzo, M.R., Brandolini, L., Russo, R., Allegretti, M.

“…•CIPN is a common and disabling side effect of antitumor agents, including paclitaxel, resulting in progressive damage of peripheral nerves.•Taxanes are…”
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Conformational Change in the Mechanism of Inclusion of Ketoprofen in β‑Cyclodextrin: NMR Spectroscopy, Ab Initio Calculations, Molecular Dynamics Simulations, and Photoreactivity by Guzzo, T, Mandaliti, W, Nepravishta, R, Aramini, A, Bodo, E, Daidone, I, Allegretti, M, Topai, A, Paci, M

“…Inclusion of drugs in cyclodextrins (CDs) is a recognized tool for modifying several properties such as solubility, stability, bioavailability, and so on. The…”
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CXCR1/2 inhibition prevents paclitaxel- and oxaliplatin-induced peripheral neuropathy by Ruffini, P.A, Brandolini, L, Russo, R, Cimini, A, Allegretti, M

“…Background: Peripheral neuropathy (PN) is a common toxicity of several chemotherapeutic agents, including taxanes and platinum. Reparixin is an…”
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Effects of Immunization with Recombinant Schistosoma mansoni Enzymes AK and HGPRT: Murine Infection Control by Fattori, Ana Carolina Maragno, Montija, Elisandra de A, Fragelli, Bruna D de L, Correia, Ricardo de O, de Castro, Cynthia Aparecida, Romanello, Larissa, Nogueira, Camila T, Allegretti, Silmara M, Soares, Edson G, Pereira, Humberto D, Anibal, Fernanda de F

“…Schistosomiasis is one of the most important human helminthiases worldwide. Praziquantel is the current treatment, and no vaccine is available until the…”
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DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats by Mistretta, Francesco A, Russo, Andrea, Castiglione, Fabio, Bettiga, Arianna, Colciago, Giorgia, Montorsi, Francesco, Brandolini, Laura, Aramini, Andrea, Bianchini, Gianluca, Allegretti, Marcello, Bovolenta, Silvia, Russo, Roberto, Benigni, Fabio, Hedlund, Petter

“…The transient receptor potential melastin 8 ion channel (TRPM8) is implicated in bladder sensing but limited information on TRPM8 antagonists in bladder…”
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Blockade of the chemokine receptor CXCR2 ameliorates adjuvant‐induced arthritis in rats by Barsante, M M, Cunha, T M, Allegretti, M, Cattani, F, Policani, F, Bizzarri, C, Tafuri, W L, Poole, S, Cunha, F Q, Bertini, R, Teixeira, M M

“…Background and purpose: Chemokine receptors CXCR1 and CXCR2 may mediate influx of neutrophils in models of acute and chronic inflammation. The potential…”
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Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non‐competitive allosteric inhibitor by Bertini, R, Barcelos, LS, Beccari, AR, Cavalieri, B, Moriconi, A, Bizzarri, C, Di Benedetto, P, Di Giacinto, C, Gloaguen, I, Galliera, E, Corsi, MM, Russo, RC, Andrade, SP, Cesta, MC, Nano, G, Aramini, A, Cutrin, JC, Locati, M, Allegretti, M, Teixeira, MM

“…BACKGROUND AND PURPOSE DF 2156A is a new dual inhibitor of IL‐8 receptors CXCR1 and CXCR2 with an optimal pharmacokinetic profile. We characterized its binding…”
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Treatment with DF 2162, a non‐competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice by Cunha, T M, Barsante, M M, Guerrero, A T, Verri, W A, Ferreira, S H, Coelho, F M, Bertini, R, Di Giacinto, C, Allegretti, M, Cunha, F Q, Teixeira, M M

“…Background and purpose: Neutrophil migration into tissues is involved in the genesis of inflammatory pain. Here, we addressed the hypothesis that the effect of…”
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Targeting C5a: recent advances in drug discovery by Allegretti, M, Moriconi, A, Beccari, A R, Di Bitondo, R, Bizzarri, C, Bertini, R, Colotta, F

“…Activation of complement via the innate and adaptive immune system is vital to the body's defences in fighting infections. Unregulated complement activation is…”
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CLINICAL PRESENTATION AND OUTCOME OF PATIENTS WITH FALSE-POSITIVE ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION by Zhu, T.R, Huitema, A, Alemayehu, M, Allegretti, M, Chomicki, C, Yadegari, A, Lavi, S

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294 The Effectiveness Of The Acute Treatment Of Infarcting Myocardium In The Elderly - Tea Time by Yadegari, A.B, Sridhar, K, Allegretti, M, Syed, J

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Photobleaching at the Surface of 1D-photonic Crystal Biochips by Sepe, E., Sinibaldi, A., Michelotti, F., Allegretti, M., Giacomini, P., Danz, N., Munzert, P., Mura, F.

“…The increasing need for early cancer diagnosis has focused research efforts on new screening technologies such as those based on cancer biomarkers. Herein, we…”
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Oocyte maturation in the sloth’s giant tick Amblyomma varium (Acari: Ixodidae) in an ecological context by Sanches, Gustavo S, André, Marcos R, do Prado, Angelo P, Allegretti, Silmara M, Remedio, Rafael N, Nunes, Pablo H, Machado, Rosangela Z, Bechara, Gervásio H, Camargo-Mathias, Maria I

“…The sloth’s giant tick Amblyomma varium Koch, which is a neotropical species that inhabits tropical rainforests, is the largest tick reported to date. The…”
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Cross-cultural adaptation and reliability analysis of the Brazilian version of Pediatric Balance Scale (PBS) by Ries, Lílian G K, Michaelsen, Stella M, Soares, Patrícia S A, Monteiro, Vanessa C, Allegretti, Kátia M G

“…The Pediatric Balance Scale (PBS) was developed from a modified version of the Berg Balance Scale aiming to obtain a balance scale more appropriate for the…”
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Therapeutic Effect of Diminazene Aceturate on Parasitic Blood Fluke Schistosoma mansoni Infection by de Brito, Mariana G, Mengarda, Ana C, Oliveira, George L, Cirino, Maria E, Silva, Tais C, de Oliveira, Rosimeire N, Allegretti, Silmara M, de Moraes, Josué

“…Praziquantel is currently the only drug available to treat schistosomiasis, a disease of enormous public health significance caused by a blood fluke of the…”
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Antiparasitic activity of nerolidol in a mouse model of schistosomiasis by Silva, Marcos P., de Oliveira, Rosimeire N., Mengarda, Ana C., Roquini, Daniel B., Allegretti, Silmara M., Salvadori, Maria C., Teixeira, Fernanda S., de Sousa, Damião P., Pinto, Pedro L.S., da Silva Filho, Ademar A., de Moraes, Josué

“…•Single oral nerolidol dose resulted in reduction of worm burden in a murine schistosomiasis model.•Oral administration of nerolidol causes reduction in…”
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Biomphalaria glabrata infected with Angiostrongylus cantonensis: Proteomic changes in the snail host by Mendes, Tiago M.F., Carrilho, Emanuel, Galinaro, Carlos A., Cabral, Fernanda J., Allegretti, Silmara M.

“…•Few immune related changes were found during infection.•Temptin-like protein levels were found up-regulated stimulating reproduction.•Reproductive stimulation…”
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Anti-Inflammatory Properties of Menthol and Menthone in Schistosoma mansoni Infection by Zaia, Mauricio G, Cagnazzo, Túlio di Orlando, Feitosa, Karina A, Soares, Edson G, Faccioli, Lúcia H, Allegretti, Silmara M, Afonso, Ana, Anibal, Fernanda de Freitas

“…Schistosomiasis is a parasitic disease caused by several species of trematode worms and it is believed that more than 261 million people are affected…”
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