Search Results - "Allard, Jeffrey"
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Circulating Tumor Cells at Each Follow-up Time Point during Therapy of Metastatic Breast Cancer Patients Predict Progression-Free and Overall Survival
Published in Clinical cancer research (15-07-2006)“…Purpose: We reported previously that ≥5 circulating tumor cells (CTC) in 7.5 mL blood at baseline and at first follow-up in 177 patients with metastatic breast…”
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Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases
Published in Clinical cancer research (15-10-2004)“…Purpose: The purpose of this study was to determine the accuracy, precision, and linearity of the CellSearch system and evaluate the number of circulating…”
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Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer
Published in The New England journal of medicine (19-08-2004)“…An automated device that separates, identifies, and enumerates epithelial cells in whole blood was used to measure levels of circulating tumor cells in women…”
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Circulating Tumor Cells: A Novel Prognostic Factor for Newly Diagnosed Metastatic Breast Cancer
Published in Journal of clinical oncology (01-03-2005)“…Metastatic breast cancer (MBC) is incurable; its treatment is palliative. We investigated whether the presence of circulating tumor cells (CTCs) predicts…”
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Soluble Mesothelin-Related Peptide Level Elevation in Mesothelioma Serum and Pleural Effusions
Published in The Annals of thoracic surgery (2008)“…Background Soluble mesothelin-related peptide (SMRP) is a potential marker for malignant pleural mesothelioma (MPM), which may be useful for screening…”
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MESOMARK™ : A potential test for malignant pleural mesothelioma
Published in Clinical chemistry (Baltimore, Md.) (01-04-2007)“…Soluble mesothelin-related peptides (SMRP)have been reported to be potential biomarkers for malignant pleural mesothelioma (MPM). We report analytical and…”
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TGF-beta utilizes SMAD3 to inhibit CD16-mediated IFN-gamma production and antibody-dependent cellular cytotoxicity in human NK cells
Published in The Journal of immunology (1950) (15-09-2008)“…TGF-beta can be a potent suppressor of lymphocyte effector cell functions and can mediate these effects via distinct molecular pathways. The role of TGF-beta…”
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The PP2A inhibitor SET regulates natural killer cell IFN-gamma production
Published in The Journal of experimental medicine (01-10-2007)“…Monokines (i.e., interleukin [IL]-12, -18, and -15) induce natural killer (NK) cells to produce interferon-gamma (IFN-gamma), which is a critical factor for…”
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A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass
Published in Gynecologic oncology (01-01-2009)“…Abstract Introduction Patients diagnosed with epithelial ovarian cancer (EOC) have improved outcomes when cared for at centers experienced in the management of…”
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The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass
Published in Gynecologic oncology (01-02-2008)“…Abstract Objectives. The CA125 tumor marker is used to help predict the presence of ovarian cancer in patients with an adnexal mass. Because elevated CA125…”
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Protein Profiling of Pleural Effusions to Identify Malignant Pleural Mesothelioma Using SELDI-TOF MS
Published in Technology in cancer research & treatment (01-10-2009)“…Diagnosis of malignant pleural mesothelioma (MM) is limited. Novel proteomic technologies can be utilized to discover changes in expression of pleural proteins…”
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Relationship of Serum HER-2/neu and Serum CA 15-3 in Patients with Metastatic Breast Cancer
Published in Clinical chemistry (Baltimore, Md.) (01-08-2002)“…Serum HER-2/neu antigen concentrations have been reported to correlate with increased tumor volume in patients with breast cancer. We measured serum CA 15-3, a…”
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CCR 20th Anniversary Commentary: Paving the Way for Circulating Tumor Cells
Published in Clinical cancer research (01-07-2015)“…Cancer cells can enter the bloodstream, form distant metastases, and ultimately lead to death. A study by Allard and colleagues, which was published in the…”
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Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus
Published in Gynecologic oncology (01-08-2008)“…Abstract Objective Tumor markers with increased sensitivity and specificity for endometrial cancer are needed to help monitor response to therapy and to detect…”
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Automated Assay for HER-2/neu in Serum
Published in Clinical chemistry (Baltimore, Md.) (01-02-2000)“…The extracellular domain of the HER-2/neu oncogene product is increased in sera of some patients with epithelial cancers. Our aim was to develop an automated…”
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Circulating tumor cells predict survival in patients with metastatic prostate cancer
Published in Urology (Ridgewood, N.J.) (01-04-2005)“…To determine whether circulating tumor cells (CTCs) predict for survival in patients with metastatic prostate cancer (PCa) and to compare its prognostic…”
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Differential expression of SHIP1 in CD56bright and CD56dim NK cells provides a molecular basis for distinct functional responses to monokine costimulation
Published in Blood (15-04-2005)“…Monocyte cytokines (ie, monokines) induce natural killer (NK) cells to produce interferon-γ (IFN-γ), which is critical for monocyte clearance of infectious…”
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Isolation and Characterization of Circulating Tumor Cells in Patients with Metastatic Colorectal Cancer
Published in Clinical colorectal cancer (01-07-2006)“…Development of targeted therapeutic agents in colorectal cancer (CRC) is impeded by the lack of a noninvasive surrogate of drug effect. This pilot study…”
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Effect of desialylation on binding, affinity, and specificity of 56 monoclonal antibodies against MUC1 mucin
Published in Tumor biology (01-01-1998)“…We evaluated 56 monoclonal antibodies (MAbs), submitted to the ISOBM TD-4 Workshop, for changes in binding following desialylation of the MUC1 molecule and for…”
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