Search Results - "Allain, Eric P."

Non-canonical transcriptional regulation of the poor prognostic factor UGT2B17 in chronic lymphocytic leukemic and normal B cells by Rouleau, Michèle, Villeneuve, Lyne, Allain, Eric P, McCabe-Leroux, Jules, Tremblay, Sophie, Nguyen Van Long, Flora, Uchil, Ashwini, Joly-Beauparlant, Charles, Droit, Arnaud, Guillemette, Chantal

“…High expression of the glycosyltransferase UGT2B17 represents an independent adverse prognostic marker in chronic lymphocytic leukemia (CLL). It also…”
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Pathogenic variants carrier screening in New Brunswick: Acadians reveal high carrier frequency for multiple genetic disorders by Robichaud, Philippe Pierre, Allain, Eric P, Belbraouet, Sarah, Bhérer, Claude, Mamelona, Jean, Harquail, Jason, Crapoulet, Stéphanie, Crapoulet, Nicolas, Bélanger, Mathieu, Ben Amor, Mouna

“…Founder populations that have recently undergone important genetic bottlenecks such as French-Canadians and Ashkenazi Jews can harbor some pathogenic variants…”
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Inactivation of Prostaglandin E2 as a Mechanism for UGT2B17-Mediated Adverse Effects in Chronic Lymphocytic Leukemia by Allain, Eric P., Rouleau, Michèle, Le, Trang, Vanura, Katrina, Villeneuve, Lyne, Caron, Patrick, Turcotte, Véronique, Lévesque, Eric, Guillemette, Chantal

“…High expression of the metabolic enzyme UDP-glucuronosyltransferase UGT2B17 in chronic lymphocytic leukemia (CLL) cells was associated with poor prognosis in…”
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Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression by Allain, Eric P., Rouleau, Michèle, Lévesque, Eric, Guillemette, Chantal

“…The best-known role of UDP-glucuronosyltransferase enzymes (UGTs) in cancer is the metabolic inactivation of drug therapies. By conjugating glucuronic acid to…”
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Application of annotation-agnostic RNA sequencing data analysis tools for biomarker discovery in liquid biopsy by Wajnberg, Gabriel, Allain, Eric P, Roy, Jeremy W, Srivastava, Shruti, Saucier, Daniel, Morin, Jr, Pier, Marrero, Alier, O'Connell, Colleen, Ghosh, Anirban, Lewis, Stephen M, Ouellette, Rodney J, Crapoulet, Nicolas

“…RNA sequencing analysis is an important field in the study of extracellular vesicles (EVs), as these particles contain a variety of RNA species that may have…”
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The Intracellular Localisation and Phosphorylation Profile of the Human 5-Lipoxygenase Δ13 Isoform Differs from That of Its Full Length Counterpart by Allain, Eric P, Boudreau, Luc H, Flamand, Nicolas, Surette, Marc E

“…5-Lipoxygenase (5-LO) catalyzes leukotriene (LT) biosynthesis by a mechanism that involves interactions with 5-lipoxygenase activating protein (FLAP) and…”
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A novel CHD3 variant in a patient with central precocious puberty: Expanded phenotype of Snijders Blok‐Campeau syndrome? by LeBreton, Laure, Allain, Eric P., Parscan, Radu Christian, Crapoulet, Nicolas, Almaghraby, Abdullah, Ben Amor, Mouna

“…Snijders Blok‐Campeau syndrome is an autosomal dominant genetic disorder first described in 2018, mostly associated with de novo variants in the CHD3 gene that…”
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Functional platelet‐derived mitochondria induce the release of human neutrophil microvesicles by Léger, Jacob L, Soucy, Marie‐France N, Veilleux, Vanessa, Foulem, Robert D, Robichaud, Gilles A, Surette, Marc E, Allain, Eric P, Boudreau, Luc H

“…Inflammation is an essential process of host defense against infections, illness, or tissue damage. Polymorphonuclear neutrophils (PMN) are among the first…”
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KLF5 and NFYA factors as novel regulators of prostate cancer cell metabolism by Poluri, Raghavendra T K, Paquette, Virginie, Allain, Éric P, Lafront, Camille, Joly-Beauparlant, Charles, Weidmann, Cindy, Droit, Arnaud, Guillemette, Chantal, Pelletier, Martin, Audet-Walsh, Étienne

“…Prostate cancer (PCa) cells rely on the androgen receptor (AR) signaling axis to reprogram metabolism to sustain aberrant proliferation. Whether additional…”
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Post-transcriptional Regulation of UGT2B10 Hepatic Expression and Activity by Alternative Splicing by Labriet, Adrien, Allain, Eric P, Rouleau, Michèle, Audet-Delage, Yannick, Villeneuve, Lyne, Guillemette, Chantal

“…The detoxification enzyme UDP-glucuronosyltransferase UGT2B10 is specialized in the N-linked glucuronidation of many drugs and xenobiotics. Preferred…”
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Expanded phenotype of primary ciliary dyskinesia related to DRC1 pathogenic variant with dysmorphisms and vascular anomalies by LeBlanc, Samuel, Allain, Eric P., Girouard, Gabriel, Mallet, Marcel, Amor, Mouna Ben

“…We present a case of a female diagnosed with primary ciliary dyskinesia (PCD) type 21 with non‐previously reported extrapulmonary symptoms, including facial…”
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Sex-dependent association of circulating sex steroids and pituitary hormones with treatment-free survival in chronic lymphocytic leukemia patients by Allain, Eric P., Venzl, Karin, Caron, Patrick, Turcotte, Véronique, Simonyan, David, Gruber, Michaela, Le, Trang, Lévesque, Eric, Guillemette, Chantal, Vanura, Katrina

“…Chronic lymphocytic leukemia (CLL) is not considered a hormone-regulated cancer although sex is a recognized risk factor with men more frequently diagnosed and…”
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UGT2B17 modifies drug response in chronic lymphocytic leukaemia by Allain, Eric P., Rouleau, Michèle, Vanura, Katrina, Tremblay, Sophie, Vaillancourt, Joanie, Bat, Vincent, Caron, Patrick, Villeneuve, Lyne, Labriet, Adrien, Turcotte, Véronique, Le, Trang, Shehata, Medhat, Schnabl, Susanne, Demirtas, Dita, Hubmann, Rainer, Joly-Beauparlant, Charles, Droit, Arnaud, Jäger, Ulrich, Staber, Philipp B., Lévesque, Eric, Guillemette, Chantal

“…Background High UGT2B17 is associated with poor prognosis in untreated chronic lymphocytic leukaemia (CLL) patients and its expression is induced in…”
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Dietary omega-3 fatty acids modulate the production of platelet-derived microvesicles in an in vivo inflammatory arthritis model by Laevski, Angela M., Doucet, Mélina R., Doucet, Marco S., LeBlanc, Audrée A., Pineau, Paskale E., Hébert, Mathieu P. A., Doiron, Jérémie A., Roy, Patrick, Mbarik, Maroua, Matthew, Alexis J., Allain, Eric P., Surette, Marc E., Boudreau, Luc H.

“…Purpose The aim of this study was to investigate the effects of different ω-3 polyunsaturated fatty acid (PUFA) enriched diets, including a novel renewable…”
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Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients by Labriet, Adrien, Lévesque, Éric, Cecchin, Erika, De Mattia, Elena, Villeneuve, Lyne, Rouleau, Michèle, Jonker, Derek, Couture, Félix, Simonyan, David, Allain, Eric P., Buonadonna, Angela, D’Andrea, Mario, Toffoli, Giuseppe, Guillemette, Chantal

“…This study investigated the potential of single nucleotide polymorphisms as predictors of survival in two cohorts comprising 417 metastatic colorectal cancer…”
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Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression by Lévesque, Eric, Labriet, Adrien, Hovington, Hélène, Allain, Éric P., Melo-Garcia, Luciana, Rouleau, Michèle, Brisson, Hervé, Turcotte, Véronique, Caron, Patrick, Villeneuve, Lyne, Leclercq, Mickaël, Droit, Arnaud, Audet-Walsh, Etienne, Simonyan, David, Fradet, Yves, Lacombe, Louis, Guillemette, Chantal

“…Background Perturbation of the major UGT2B17-dependent androgen catabolism pathway has the potential to affect prostate cancer (PCa) progression. The objective…”
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A Non-Canonical Role for the Glycosyltransferase Enzyme UGT2B17 as a Novel Constituent of the B Cell Receptor Signalosome by Wagner, Antoine, Rouleau, Michèle, Villeneuve, Lyne, Le, Trang, Peltier, Cheryl, Allain, Éric P, Beaudoin, Caroline, Tremblay, Sophie, Courtier, Fréderic, Nguyen Van Long, Flora, Laverdière, Isabelle, Lévesque, Éric, Banerji, Versha, Vanura, Katrina, Guillemette, Chantal

“…In chronic lymphocytic leukemia (CLL), an elevated glycosyltransferase UGT2B17 expression (UGT2B17 ) identifies a subgroup of patients with shorter survival…”
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Abstract 1381: Characterization of the 12-lipoxygenase expression in the megakaryoblastic cell line, Dami by Boudreau, Luc H., Gauvin, Vanessa L., Richard, Jaël, Soucy, Marie-France N., Hébert, Mathieu P.A., Allain, Eric P.

“…Abstract Megakaryocytes are myeloid cells produced primarily in the bone marrow and are best known for releasing platelets in the blood stream. In the platelet…”
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Abstract 5237: Sex-dependent association of circulating sex steroids, pituitary hormones and treatment-free survival in patients with chronic lymphocytic leukemia by Allain, Eric P., Venzl, Karin, Caron, Patrick, Turcotte, Véronique, Simonyan, David, Gruber, Michaela, Le, Trang, Lévesque, Éric, Guillemette, Chantal, Vanura, Katrina

“…Abstract Chronic lymphocytic leukemia (CLL) is the most frequent adult leukemia in the western world, and is not considered a hormone-regulated cancer but sex…”
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Inactivation of Prostaglandin E 2 as a Mechanism for UGT2B17-Mediated Adverse Effects in Chronic Lymphocytic Leukemia by Allain, Eric P, Rouleau, Michèle, Le, Trang, Vanura, Katrina, Villeneuve, Lyne, Caron, Patrick, Turcotte, Véronique, Lévesque, Eric, Guillemette, Chantal

“…High expression of the metabolic enzyme UDP-glucuronosyltransferase UGT2B17 in chronic lymphocytic leukemia (CLL) cells was associated with poor prognosis in…”
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