Search Results - "Alkhathami, Ali G."
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Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach
Published in Vaccines (Basel) (25-01-2022)“…Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over some time, thus protecting the bacteria against antibiotics. AR is…”
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Bone morphogenetic protein (BMP)9 in cancer development: mechanistic, diagnostic, and therapeutic approaches?
Published in Journal of drug targeting (09-08-2023)“…Bone morphogenetic protein (BMP)-9 is considered a member of the transforming growth factor (TGF)β superfamily. It was first found as an inducer of bone and…”
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In Vitro Evaluation of Antioxidant, Anticancer, and Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum
Published in Frontiers in pharmacology (19-07-2022)“…Adenium obesum commonly known as “desert rose” belongs to the family Apopcynaceae and has previously been reported for its anti-influenza, antimicrobial, and…”
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Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations
Published in Frontiers in pharmacology (09-08-2022)“…Poly [adenosine diphosphate (ADP)-ribose] polymerases (PARPs) are members of a family of 17 enzymes that performs several fundamental cellular processes…”
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Molecular pathways in the development of HPV-induced oropharyngeal cancer
Published in Cell communication and signaling (14-12-2023)“…Oropharyngeal cancer, a subset of head and neck cancer, is increasingly recognized as a unique clinical entity primarily influenced by high-risk human…”
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Increased mRNA expression of key cytokines among suspected cases of Pneumocystis jirovecii infection
Published in BMC infectious diseases (07-01-2021)“…Pneumocystis pneumonia (PCP) is a fatal infectious disease caused by Pneumocystis jirovecii (PJP). The major factor relevant to morbidity and mortality seems…”
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Isolated and Combined Effect of Age and Gender on Neutrophil-Lymphocyte Ratio in the Hyperglycemic Saudi Population
Published in Medicina (Kaunas, Lithuania) (03-08-2022)“…Inflammation is pivotal to the pathogenesis of diabetes mellitus (DM), but pathological alterations of the neutrophil−lymphocyte ratio (NLR), an emerging…”
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Nanomedicine-Based Drug-Targeting in Breast Cancer: Pharmacokinetics, Clinical Progress, and Challenges
Published in ACS omega (26-12-2023)“…Breast cancer (BC) is a malignant neoplasm that begins in the breast tissue. After skin cancer, BC is the second most common type of cancer in women. At the…”
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Cydonia oblonga extract mediated biosynthesis of gold nanoparticles: Analysis of its anti-oral cancer and antioxidant properties
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-02-2025)“…[Display omitted] •Green synthesis of gold nanoparticles sing Cydonia oblonga seed extract.•Cydonia oblonga seed extract utilized as effective reducing agent…”
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Bionanofabrication of Cupric oxide catalyst from Water hyacinth based carbohydrate and its impact on cellulose deconstructing enzymes production under solid state fermentation
Published in International journal of biological macromolecules (01-12-2023)“…One of the most important properties of cellulolytic enzyme is its ability to convert cellulosic polymer into monomeric fermentable sugars which are…”
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Assessment of vitamin D status and associated risk factors in high-altitude populations affected by multiple sclerosis: A case-control study
Published in Medicine (Baltimore) (31-05-2024)“…Several studies have suggested a correlation between serum vitamin D (VitD) level and multiple sclerosis (MS). MS has a known latitudinal distribution pattern,…”
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Glycolysis in human cancers: Emphasis circRNA/glycolysis axis and nanoparticles in glycolysis regulation in cancer therapy
Published in Environmental research (01-10-2023)“…The metabolism of cancer has been an interesting hallmark and metabolic reprogramming, especially the change from oxidative phosphorylation in mitochondria to…”
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Serum-Based lncRNA ANRIL, TUG1, UCA1, and HIT Expressions in Breast Cancer Patients
Published in Disease markers (2022)“…Breast cancer is a heterogeneous disease and is the most common and prevalent form of malignancy diagnosed in women. lncRNAs are found to be frequently…”
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Pan-Genome Analysis of Oral Bacterial Pathogens to Predict a Potential Novel Multi-Epitopes Vaccine Candidate
Published in International journal of environmental research and public health (09-07-2022)“…Porphyromonas gingivalis is a Gram-negative anaerobic bacterium, mainly present in the oral cavity and causes periodontal infections. Currently, no licensed…”
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BOLA family genes are the drivers and potential biomarkers of survival in kidney renal clear cell carcinoma patients
Published in Saudi medical journal (01-11-2024)“…[Please see PDF for full article text]…”
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Association of disease severity and death outcome with vaccination status of admitted COVID-19 patients in delta period of SARS-COV-2 in mixed variety of vaccine background
Published in Saudi journal of biological sciences (01-07-2022)“…To understand the effectual role of COVID-19 vaccination, we must analyze its effectiveness in dampening the disease severity and death outcome in patients who…”
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Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect of Carica papaya Leaves Confirmed by Histopathology, Immunohistochemistry, and Gene Expression Studies
Published in ACS omega (20-06-2023)“…The present study analyzes the efficacy of the ethanolic extract of C. papaya leaves (ECP) against HgCl2-induced nephrotoxicity. The effects on the biochemical…”
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Role of miRNA-495 and NRXN-1 and CNTN-1 mRNA Expression and Its Prognostic Importance in Breast Cancer Patients
Published in Journal of oncology (08-10-2021)“…Breast cancer is a heterogeneous disease in which genetic factors are involved in disease worsening and higher mortality. Epidemiological and clinical research…”
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Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates
Published in Saudi medical journal (01-02-2021)“…To explore the antibacterial activity of thymoquinone (TQ), a quinone extracted from . This study was conducted from May 2019 to March 2020 at the Department…”
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