The quality of life in Alzheimer’s disease is not associated with handgrip strength but with activities of daily living–a composite study from 28 European countries

The quality of life in Alzheimer’s disease is not associated with handgrip strength but with activities of daily living–a composite study from 28 European countries

Abstract Objectives The relationship between handgrip strength (HGS) and quality of life is inconsistent. The purpose of this study was to investigate the potential association between HGS and quality of life in the settings of ageing and Alzheimer’s disease (AD). Methods We investigated the HGS, CA...

Full description

Saved in:
Bibliographic Details
Published in:BMC geriatrics Vol. 23; no. 1; pp. 1 - 8
Main Authors: Qaisar, Rizwan, Hussain, M Azhar, Karim, Asima, Ahmad, Firdos, Franzese, Fabio, Al-Masri, Abeer A, Alsaad, Saad M, Alkahtani, Shaea Ayed
Format: Journal Article
Language:English
Published: London BioMed Central Ltd 04-09-2023
BioMed Central
BMC
Subjects:
Activities of daily living
Advertising executives
Aging
Alzheimer's disease
CASP-12
Datasets
Diabetes
Geriatrics
Handgrip strength
Hypertension
Kidney diseases
Lung diseases
Medical research
Medicine, Experimental
Neurodegenerative diseases
Older people
Quality of life
Quantitative psychology
Questionnaires
Sarcopenia
Self-actualization
SHARE
Surveys
Europe
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Objectives The relationship between handgrip strength (HGS) and quality of life is inconsistent. The purpose of this study was to investigate the potential association between HGS and quality of life in the settings of ageing and Alzheimer’s disease (AD). Methods We investigated the HGS, CASP-12 (control, autonomy, self-realization, and pleasure) measure of quality of life, and physical capacity in European adults above 50, including controls (n = 38,628) and AD subjects (n = 460) using the survey of health, ageing, and retirement in Europe (SHARE; 2022). Results AD subjects exhibited lower HGS and CASP-12 scores than controls (both p < 0.05). Participants with higher CASP-12 quartiles had higher HGS in controls but not in AD subjects. A linear positive relation was found between HGS and CASP-12 in controls (0.0842, p < 0.05) but not in AD subjects (0.0636, p = 0.091). There was no effect of gender on this finding. Lastly, we found significant negative associations of difficulties walking, rising from chair, climbing stairs, and fatigue with CASP-12 scores in controls and AD subjects (all p < 0.05). Conclusions Altogether, HGS was not associated with quality of life in individuals with AD. Conversely, difficulties in activities of daily living seem to be negatively associated with quality of life; thus, strategies are recommended to improve physical capacity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1471-2318
1471-2318
DOI:10.1186/s12877-023-04233-1