Search Results - "Aljarf, Raghad"

Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2 by Aljarf, Raghad, Shen, Mengyuan, Pires, Douglas E. V., Ascher, David B.

“…BRCA1 and BRCA2 are tumour suppressor genes that play a critical role in maintaining genomic stability via the DNA repair mechanism. DNA repair defects caused…”
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piscesCSM: prediction of anticancer synergistic drug combinations by AlJarf, Raghad, Rodrigues, Carlos H. M., Myung, Yoochan, Pires, Douglas E. V., Ascher, David B.

“…While drug combination therapies are of great importance, particularly in cancer treatment, identifying novel synergistic drug combinations has been a…”
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embryoTox: Using Graph-Based Signatures to Predict the Teratogenicity of Small Molecules by Aljarf, Raghad, Tang, Simon, Pires, Douglas E. V., Ascher, David B.

“…Teratogenic drugs can lead to extreme fetal malformation and consequently critically influence the fetus’s health, yet the teratogenic risks associated with…”
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cardioToxCSM: A Web Server for Predicting Cardiotoxicity of Small Molecules by Iftkhar, Saba, de Sá, Alex G. C., Velloso, João P. L., Aljarf, Raghad, Pires, Douglas E. V., Ascher, David B.

“…The design of novel, safe, and effective drugs to treat human diseases is a challenging venture, with toxicity being one of the main sources of attrition at…”
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