Search Results - "Aliyari, Roghiyh"

Systematic identification of type I and type II interferon-induced antiviral factors by Liu, Su-Yang, Sanchez, David Jesse, Aliyari, Roghiyh, Lu, Sun, Cheng, Genhong

“…Type I and type II interferons (IFNs) are cytokines that establish the cellular antiviral state through the induction of IFN-stimulated genes (ISGs). We sought…”
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Interleukin-8 as a Biomarker for Disease Prognosis of Coronavirus Disease-2019 Patients by Li, Lili, Li, Jie, Gao, Meiling, Fan, Huimin, Wang, Yanan, Xu, Xin, Chen, Chunfeng, Liu, Junxiao, Kim, Jocelyn, Aliyari, Roghiyh, Zhang, Jicai, Jin, Yujie, Li, Xiaorong, Ma, Feng, Shi, Minxin, Cheng, Genhong, Yang, Heng

“…The widespread prevalence of coronavirus disease-2019 (COVID-19) which is caused by severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has…”
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RNA-based viral immunity initiated by the Dicer family of host immune receptors by Aliyari, Roghiyh, Ding, Shou-Wei

“…Suppression of viral infection by RNA in a nucleotide sequence homology-dependent manner was first reported in plants in early 1990s. Studies in the past 15…”
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Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection by Watanabe, Momoko, Buth, Jessie E., Vishlaghi, Neda, de la Torre-Ubieta, Luis, Taxidis, Jiannis, Khakh, Baljit S., Coppola, Giovanni, Pearson, Caroline A., Yamauchi, Ken, Gong, Danyang, Dai, Xinghong, Damoiseaux, Robert, Aliyari, Roghiyh, Liebscher, Simone, Schenke-Layland, Katja, Caneda, Christine, Huang, Eric J., Zhang, Ye, Cheng, Genhong, Geschwind, Daniel H., Golshani, Peyman, Sun, Ren, Novitch, Bennett G.

“…The human cerebral cortex possesses distinct structural and functional features that are not found in the lower species traditionally used to model brain…”
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25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model by Li, Chunfeng, Deng, Yong-Qiang, Wang, Shuo, Ma, Feng, Aliyari, Roghiyh, Huang, Xing-Yao, Zhang, Na-Na, Watanabe, Momoko, Dong, Hao-Long, Liu, Ping, Li, Xiao-Feng, Ye, Qing, Tian, Min, Hong, Shuai, Fan, Junwan, Zhao, Hui, Li, Lili, Vishlaghi, Neda, Buth, Jessie E., Au, Connie, Liu, Ying, Lu, Ning, Du, Peishuang, Qin, F. Xiao-Feng, Zhang, Bo, Gong, Danyang, Dai, Xinghong, Sun, Ren, Novitch, Bennett G., Xu, Zhiheng, Qin, Cheng-Feng, Cheng, Genhong

“…Zika virus (ZIKV) has become a public health threat due to its global transmission and link to severe congenital disorders. The host immune responses to ZIKV…”
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Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation by Tan, Guangyun, Yi, Zhaohong, Song, Hongxiao, Xu, Fengchao, Li, Feng, Aliyari, Roghiyh, Zhang, Hong, Du, Peishuang, Ding, Yanhua, Niu, Junqi, Wang, Xiaosong, Su, Lishan, Qin, F. Xiao-Feng, Cheng, Genhong

“…To understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect of interferon (IFN) therapy, we conduct high-throughput bimolecular…”
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Mechanism of induction and suppression of antiviral immunity directed by virus-derived small RNAs in Drosophila by Aliyari, Roghiyh, Wu, Qingfa, Li, Hong-Wei, Wang, Xiao-Hong, Li, Feng, Green, Lance D, Han, Cliff S, Li, Wan-Xiang, Ding, Shou-Wei

“…The small RNA-directed viral immunity pathway in plants and invertebrates begins with the production by Dicer nuclease of virus-derived siRNAs (viRNAs), which…”
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RNA-Based Immunity Terminates Viral Infection in Adult Drosophila in the Absence of Viral Suppression of RNA Interference: Characterization of Viral Small Interfering RNA Populations in Wild-Type and Mutant Flies by HAN, Yan-Hong, LUO, Ying-Jun, QINGFA WU, JOVEL, Juan, WANG, Xiao-Hong, ALIYARI, Roghiyh, CHENGGUI HAN, LI, Wan-Xiang, DING, Shou-Wei

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5 by Zhang, Peng, Reichardt, Anna, Liang, Huanhuan, Aliyari, Roghiyh, Cheng, David, Wang, Yaya, Xu, Feng, Cheng, Genhong, Liu, Yingfang

“…The TRAF [tumor necrosis factor receptor-associated factor] family of cytoplasmic adaptor proteins link cell-surface receptors to intracellular signaling…”
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A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling by Parvatiyar, Kislay, Pindado, Jose, Dev, Anurupa, Aliyari, Saba Roghiyh, Zaver, Shivam A., Gerami, Hoda, Chapon, Maxime, Ghaffari, Amir A., Dhingra, Anant, Cheng, Genhong

“…Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species…”
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Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice by Li, Chunfeng, Zhu, Xingliang, Ji, Xue, Quanquin, Natalie, Deng, Yong-Qiang, Tian, Min, Aliyari, Roghiyh, Zuo, Xiangyang, Yuan, Ling, Afridi, Shabbir Khan, Li, Xiao-Feng, Jung, Jae U., Nielsen-Saines, Karin, Qin, Frank Xiao-Feng, Qin, Cheng-Feng, Xu, Zhiheng, Cheng, Genhong

“…Zika virus (ZIKV) has become a global public health emergency due to its rapidly expanding range and its ability to cause severe congenital defects such as…”
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From Mosquitos to Humans: Genetic Evolution of Zika Virus by Wang, Lulan, Valderramos, Stephanie G., Wu, Aiping, Ouyang, Songying, Li, Chunfeng, Brasil, Patricia, Bonaldo, Myrna, Coates, Thomas, Nielsen-Saines, Karin, Jiang, Taijiao, Aliyari, Roghiyh, Cheng, Genhong

“…Initially isolated in 1947, Zika virus (ZIKV) has recently emerged as a significant public health concern. Sequence analysis of all 41 known ZIKV RNA open…”
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Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol by Liu, Su-Yang, Aliyari, Roghiyh, Chikere, Kelechi, Li, Guangming, Marsden, Matthew D., Smith, Jennifer K., Pernet, Olivier, Guo, Haitao, Nusbaum, Rebecca, Zack, Jerome A., Freiberg, Alexander N., Su, Lishan, Lee, Benhur, Cheng, Genhong

“…Interferons (IFN) are essential antiviral cytokines that establish the cellular antiviral state through upregulation of hundreds of interferon-stimulated genes…”
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Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms by Chen, Yongzhi, Wang, Shanshan, Yi, Zhaohong, Tian, Huabin, Aliyari, Roghiyh, Li, Yanhua, Chen, Gang, Liu, Ping, Zhong, Jin, Chen, Xinwen, Du, Peishuang, Su, Lishan, Qin, F. Xiao-Feng, Deng, Hongyu, Cheng, Genhong

“…Cholesterol 25-hydroxylase (CH25H) as an interferon-stimulated gene (ISG) has recently been shown to exert broad antiviral activity through the production of…”
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RNA Interference Directs Innate Immunity Against Viruses in Adult Drosophila by Wang, Xiao-Hong, Aliyari, Roghiyh, Li, Wan-Xiang, Li, Hong-Wei, Kim, Kevin, Carthew, Richard, Atkinson, Peter, Ding, Shou-Wei

“…Innate immunity against bacterial and fungal pathogens is mediated by Toll and immune deficiency (Imd) pathways, but little is known about the antiviral…”
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RNA-based viral immunity initiated by the Dicer family of host immune receptors: Innate Recognition: Receptors & Signaling by ALIYARI, Roghiyh, DING, Shou-Wei

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Methods to Identify Immunogenic Peptides in SARS‐CoV‐2 Spike and Protective Monoclonal Antibodies in COVID‐19 Patients by Li, Lili, Gao, Meiling, Li, Jie, Zu, Shulong, Wang, Yanan, Chen, Chunfeng, Wan, Dingyi, Duan, Jing, Aliyari, Roghiyh, Wang, Jingfeng, Zhang, Jicai, Jin, Yujie, Huang, Weijin, Jin, Xiaoxia, Shi, Minxin, Wang, Youchun, Qin, Cheng‐Feng, Yang, Heng, Cheng, Genhong

“…The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and the associated COVID‐19 diseases are an emerging threat to global public health…”
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Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction by Chapon, Maxime, Parvatiyar, Kislay, Aliyari, Saba Roghiyh, Zhao, Jeffrey S, Cheng, Genhong

“…In spite of several decades of research focused on understanding the biology of human herpes simplex virus 1 (HSV-1), no tool has been developed to study its…”
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Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction by Chapon, Maxime, Parvatiyar, Kislay, Aliyari, Saba Roghiyh, Zhao, Jeffrey S., Cheng, Genhong

“…This work is the first to report the use of a high-throughput mutagenesis method to study the genome of HSV-1. We report three novel viral proteins potentially…”
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Mechanism of induction and suppression of antiviral immunity directed by small RNAs in Drosophila by Aliyari, Roghiyh, Wu, Qingfa, Li, Hong-Wei, Wang, Xiao-Hong, Li, Feng, Green, Lance D, Han, Cliff S, Li, Wan-Xiang, Ding, Shou-Wei

“…The identity of the viral RNA recognized directly during infection by diverse host innate immune receptors has been under debate. Here we examined the…”
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