Search Results - "Aliotta, Jason"
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Exosomes induce and reverse monocrotaline-induced pulmonary hypertension in mice
Published in Cardiovascular research (01-06-2016)“…Extracellular vesicles (EVs) from mice with monocrotaline (MCT)-induced pulmonary hypertension (PH) induce PH in healthy mice, and the exosomes (EXO) fraction…”
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2
Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming
Published in Stem cell research & therapy (03-09-2015)“…Growing evidence suggests that transcriptional regulators and secreted RNA molecules encapsulated within membrane vesicles modify the phenotype of target…”
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3
Cellular phenotype switching and microvesicles
Published in Advanced drug delivery reviews (30-09-2010)“…Cell phenotype alteration by cell-derived vesicles presents a new aspect for consideration of cell fate. Accumulating data indicates that vesicles from many…”
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Mesenchymal Stem Cell Extracellular Vesicles Reverse Sugen/Hypoxia Pulmonary Hypertension in Rats
Published in American journal of respiratory cell and molecular biology (01-05-2020)“…Mesenchymal stem cell extracellular vesicles attenuate pulmonary hypertension, but their ability to reverse established disease in larger animal models and the…”
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Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice
Published in Cardiovascular research (01-12-2013)“…Circulating endothelium-derived extracellular vesicles (EV) levels are altered in pulmonary arterial hypertension (PAH) but whether they are biomarkers of…”
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Comparison of analogue and electronic stethoscopes for pulmonary auscultation by internal medicine residents
Published in Postgraduate medical journal (01-12-2018)“…BackgroundElectronic stethoscopes are becoming more common in clinical practice. They may improve the accuracy and efficiency of pulmonary auscultation, but…”
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Culture of pulmonary artery endothelial cells from pulmonary artery catheter balloon tips: considerations for use in pulmonary vascular disease
Published in The European respiratory journal (01-03-2020)“…Endothelial dysfunction is a hallmark of pulmonary arterial hypertension (PAH) but there are no established methods to study pulmonary artery endothelial cells…”
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Cellular phenotype and extracellular vesicles: basic and clinical considerations
Published in Stem cells and development (01-07-2014)“…Early work on platelet and erythrocyte vesicles interpreted the phenomena as a discard of material from cells. Subsequently, vesicles were studied as possible…”
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Multidisciplinary Care Teams in Acute Cardiovascular Care: A Review of Composition, Logistics, Outcomes, Training, and Future Directions
Published in Journal of cardiac failure (01-10-2024)“…•Patients in the cardiac intensive care unit have become increasingly complex and require multidisciplinary care.•There are limited and heterogeneous data on…”
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Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription
Published in Experimental hematology (01-03-2010)“…Objective Microvesicles have been shown to mediate intercellular communication. Previously, we have correlated entry of murine lung-derived microvesicles into…”
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Stem cell plasticity revisited: The continuum marrow model and phenotypic changes mediated by microvesicles
Published in Experimental hematology (01-07-2010)“…The phenotype of marrow hematopoietic stem cells is determined by cell-cycle state and microvesicle entry into the stem cells. The stem cell population is…”
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Endothelial to haematopoietic transition contributes to pulmonary arterial hypertension
Published in Cardiovascular research (01-11-2017)“…The pathogenic mechanisms of pulmonary arterial hypertension (PAH) remain unclear, but involve dysfunctional endothelial cells (ECs), dysregulated immunity and…”
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Low dose 100 cGy irradiation as a potential therapy for pulmonary hypertension
Published in Journal of cellular physiology (01-11-2019)“…Pulmonary hypertension (PH) is an incurable disease characterized by pulmonary vascular remodeling and ultimately death. Two rodent models of PH include…”
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Low dose 100cGy irradiation as a potential therapy for pulmonary hypertension
Published in Journal of cellular physiology (01-11-2019)“…Pulmonary hypertension (PH) is an incurable disease characterized by pulmonary vascular remodeling and ultimately death. Two rodent models of PH include…”
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The Paradoxical Dynamism of Marrow Stem Cells: Considerations of Stem Cells, Niches, and Microvesicles
Published in Stem cell reviews (01-09-2008)“…Marrow stem cell regulation represents a complex and flexible system. It has been assumed that the system was intrinsically hierarchical in nature, but recent…”
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Mesenchymal Stem Cell Extracellular Vesicles Reverse Sugen/Hypoxia Pulmonary Hypertension in Rats
Published in American journal of respiratory cell and molecular biology (01-05-2020)Get full text
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17
Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells
Published in Proteomics (Weinheim) (01-07-2012)“…HIV‐1 infection causes profound effects both inside and outside of cells through multiple mechanisms, including those mediated by exosomes. Using the technique…”
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Daily rhythms influence the ability of lung-derived extracellular vesicles to modulate bone marrow cell phenotype
Published in PloS one (26-11-2018)“…Extracellular vesicles (EVs) are important mediators of intercellular communication and have been implicated in myriad physiologic and pathologic processes…”
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Alteration of Marrow Cell Gene Expression, Protein Production, and Engraftment into Lung by Lung‐Derived Microvesicles: A Novel Mechanism for Phenotype Modulation
Published in Stem cells (Dayton, Ohio) (01-09-2007)“…Numerous animal studies have demonstrated that adult marrow‐derived cells can contribute to the cellular component of the lung. Lung injury is a major variable…”
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Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles
Published in Stem cells and development (01-07-2012)“…We have shown that hematopoietic stem/progenitor cell phenotype and differentiative potential change throughout cell cycle. Lung-derived microvesicles (LDMVs)…”
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