Search Results - "Alinde, Berenice"
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Premature skewing of T cell receptor clonality and delayed memory expansion in HIV-exposed infants
Published in Nature communications (14-05-2024)“…While preventing vertical HIV transmission has been very successful, HIV-exposed uninfected infants (iHEU) experience an elevated risk to infections compared…”
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Reduced anti-viral IgG repertoire in HIV-exposed but uninfected infants compared to HIV-unexposed infants
Published in iScience (19-07-2024)“…Infants who are HIV exposed but uninfected (iHEU) have higher risk of viral infections compared to infants who are HIV unexposed (iHUU). We explored the effect…”
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Bacille Calmette-Guérin Vaccine Strain Modulates the Ontogeny of Both Mycobacterial-Specific and Heterologous T Cell Immunity to Vaccination in Infants
Published in Frontiers in immunology (01-10-2019)“…Differences in Bacille Calmette-Guérin (BCG) immunogenicity and efficacy have been reported, but various strains of BCG are administered worldwide. Since BCG…”
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Stereotypic expansion of Tregulatory and Th17 cells during infancy is disrupted by HIV exposure and gut epithelial damage
Published in The Journal of immunology (1950) (24-11-2021)“…Few studies have investigated immune cell ontogeny throughout the neonatal and early paediatric period, where there is often increased vulnerability to…”
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Stereotypic Expansion of T Regulatory and Th17 Cells during Infancy Is Disrupted by HIV Exposure and Gut Epithelial Damage
Published in The Journal of immunology (1950) (01-01-2022)“…Few studies have investigated immune cell ontogeny throughout the neonatal and early pediatric period, when there is often increased vulnerability to…”
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A randomized clinical trial of on-demand oral pre-exposure prophylaxis does not modulate lymphoid/myeloid HIV target cell density in the foreskin
Published in AIDS (London) (01-09-2023)“…As topical pre-exposure prophylaxis (PrEP) has been shown to cause immune modulation in rectal or cervical tissue, our aim was to examine the impact of oral…”
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Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial
Published in EBioMedicine (01-07-2023)“…The efficacy of on-demand HIV pre-exposure prophylaxis (PrEP) for men in sub-Saharan Africa has not been evaluated, and the on-demand PrEP dosing requirement…”
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Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trialResearch in context
Published in EBioMedicine (01-07-2023)“…Background: The efficacy of on-demand HIV pre-exposure prophylaxis (PrEP) for men in sub-Saharan Africa has not been evaluated, and the on-demand PrEP dosing…”
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