Search Results - "Alimova, Irina N."

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro by Alimova, Irina N., Liu, Bolin, Fan, Zeying, Edgerton, Susan M., Dillon, Thomas, Lind, Stuart E., Thor, Ann D.

“…The anti-diabetic drug metformin reduces human cancer incidence and improves the survival of cancer patients, including those with breast cancer. We studied…”
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Metformin induces unique biological and molecular responses in triple negative breast cancer cells by Liu, Bolin, Fan, Zeying, Edgerton, Susan M., Deng, Xin-Sheng, Alimova, Irina N., Lind, Stuart E., Thor, Ann D.

“…Triple negative (TN) breast cancer is more frequent in women who are obese or have type II diabetes, as well as young Women of Color. These cancers do not…”
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Loss of CAK phosphorylation of RARα mediates transcriptional control of retinoid-induced cancer cell differentiation by Wang, Anxun, Alimova, Irina N, Luo, Peihua, Jong, Ambrose, Triche, Timothy J, Wu, Lingtao

“…Although the role of the classic retinoic acid (RA)-induced genomic pathway in cancer cell differentiation is well recognized, the underlying mechanisms remain…”
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The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER‐2/neu transgenic mice by Anisimov, Vladimir N., Alimova, Irina N., Baturin, Dmitri A., Popovich, Irina G., Zabezhinski, Mark A., Manton, Kenneth G., Semenchenko, Anna V., Yashin, Anatoly I.

“…The effect of various regimens of treatment with melatonin on the development of mammary tumors in HER2/neu transgenic mice was investigated. Female HER‐2/neu…”
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Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging by Anisimov, Vladimir N, Zabezhinski, Mark A, Popovich, Irina G, Pliss, Gennady B, Bespalov, Vladimir G, Alexandrov, Valeri A, Stukov, Alexander N, Anikin, Ivan V, Alimova, Irina N, Egormin, Peter А, Panchenko, Andrey V, Piskunova, Tatiana S, Semenchenko, Anna V, Tyndyk, Margarita L, Yurova, Maria N

“…There is a growing scientific and public interest in the development of new antiaging drugs for the purposes of extending mean and/or maximum life span,…”
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Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice by Anisimov, Vladimir N, Alimova, Irina N, Baturin, Dmitri A, Popovich, Irina G, Zabezhinski, Mark A, Rosenfeld, Svetlana V, Manton, Kenneth G, Semenchenko, Anna V, Yashin, Anatoli I

“…From the age of 3 months until their natural death, female Swiss-derived SHR mice were given melatonin with their drinking water (2 or 20 mg/l) for 5…”
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Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice by Anisimov, Vladimir N., Khavinson, Vladimir KH, Provinciali, Mauro, Alimova, Irina N., Baturin, Dmitri A., Popovich, Irina G., Zabezhinski, Mark A., Imyanitov, Eugeni N., Mancini, Romina, Franceschi, Claudio

“…Female FVB/N HER‐2/neu transgenic mice from the age of 2 months were subcutaneously injected with saline, the peptide Epitalon® (Ala‐Glu‐Asp‐Gly) or with the…”
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Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice by Popovich, Irina G., Voitenkov, Boris O., Anisimov, Vladimir N., Ivanov, Vadim T., Mikhaleva, Inessa I., Zabezhinski, Mark A., Alimova, Irina N., Baturin, Dmitri A., Zavarzina, Natalia Yu, Rosenfeld, Svetlana V., Semenchenko, Anna V., Yashin, Anatoli I.

“…From the age of 3 months until their natural deaths, female Swiss-derived SHR mice were subcutaneously injected 5 consecutive days every month with 0.1 ml of…”
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Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice by Anisimov, Vladimir N., Popovich, Irina G., Alimova, Irina N., Zabezhinski, Mark A., Semenchenko, Anna V., Yashin, Anatoli I.

“…We studied effect of pregnancy and ovariectomy on the development of mammary tumors in homozygous female HER-2/neutransgenic mice. The mean life span of…”
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Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice by ANISIMOV, Vladimir N, KHAVINSON, Vladimir Kh, POPOVICH, Irina G, ZABEZHINSKI, Mark A, ALIMOVA, Irina N, ROSENFELD, Svetlana V, ZAVARZINA, Natalia Yu, SEMENCHENKO, Anna V, YASHIN, Anatoli I

“…From the age of 3 months until their natural deaths, female outbred Swiss-derived SHR mice were subcutaneously injected on 5 consecutive days every month with…”
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A clinical case of a new coronavirus infection (COVID-19) with fatal outcome in a patient with tuberous sclerosis by Kvasova, O.G., Tomashevskaya, Yu.A., Alimova, I.N., Klimova, E.A., Sadovnikova, E.A.

“…Background. Tuberous sclerosis (TS) is a genetically determined disease with an autosomal dominant type of inheritance. In the population, TS occurs with a…”
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Abstract 3446: Inhibition of EZH2 suppresses medulloblastoma cell growth by Alimova, Irina N., Venkataraman, Sujatha, Harris, Peter, Vibhakar, Rajeev

“…EZH2 (enhancer of zeste homologue2) is a polycomb group protein that mediates repression of gene transcription through its Histone 3 Lysine 27methyltransferase…”
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Abstract 2483: Inhibition of the polycomb group gene EZH2 suppresses growth and radiosensitizes ATRT cells by promoting senescence and inhibiting the CycinD-E2F1 axis by Alimova, Irina N., Venkataraman, Sujatha, Harris, Peter, Marquez, Victor E., Birks, Diane, Foreman, Nicholas K., Vibhakar, Rajeev

“…Overexpression of the polycomb group gene Enhancer of Zeste 2 (EZH2) occurs in many tumors including prostate cancer, breast cancer and brain tumors such as…”
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Loss of CAK phosphorylation of RARa mediates transcriptional control of retinoid‐induced cancer cell differentiation by Wang, Anxun, Alimova, Irina N., Luo, Peihua, Jgon, Ambrose, Triche, Timothy J., Wu, Lingtao

“…Although the role of the classic retinoic acid (RA)‐induced genomic pathway in cancer cell differentiation is well recognized, the underlying mechanisms remain…”
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Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation by Wang, Anxun, Alimova, Irina N, Luo, Peihua, Jong, Ambrose, Triche, Timothy J, Wu, Lingtao

“…Although the role of the classic retinoic acid (RA)-induced genomic pathway in cancer cell differentiation is well recognized, the underlying mechanisms remain…”
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Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice by ANISIMOV, Vladimir N, POPOVICH, Irina G, ALIMOVA, Irina N, ZABEZHINSKI, Mark A, SEMENCHENKO, Anna V, YASHIN, Anatoli I

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The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice by ANISIMOV, Vladimir N, ALIMOVA, Irina N, BATURIN, Dmitri A, POPOVICH, Irina G, ZABEZHINSKI, Mark A, MANTON, Kenneth G, SEMENCHENKO, Anna V, YASHIN, Anatoly I

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Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice by POPOVICH, Irina G, VOITENKOV, Boris O, SEMENCHENKO, Anna V, YASHIN, Anatoli I, ANISIMOV, Vladimir N, IVANOV, Vadim T, MIKHALEVA, Inessa I, ZABEZHINSKI, Mark A, ALIMOVA, Irina N, BATURIN, Dmitri A, ZAVARZINA, Natalia Yu, ROSENFELD, Svetlana V

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