Search Results - "Alimoghaddam, Kamran"
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A review of arsenic trioxide and acute promyelocytic leukemia
Published in International journal of hematology- oncology and stem cell research (01-07-2014)“…Arsenic Trioxide is an old drug that has recently re- introduced into new medicine. It is very potent against a specific type of leukemic cells harboring…”
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Randomized placebo-controlled trial of mesenchymal stem cell transplantation in decompensated cirrhosis
Published in Liver international (01-11-2013)“…Background & Aims There has been great interest in recent years to take advantage of bone marrow stem cells to treat cirrhosis. Our uncontrolled trial showed…”
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Phase II Study of Single-Agent Arsenic Trioxide for the Front-Line Therapy of Acute Promyelocytic Leukemia
Published in Journal of clinical oncology (10-07-2011)“…The long-term follow-up results of patients with acute promyelocytic leukemia (APL) treated with all-trans retinoic acid and chemotherapy show high cure rates…”
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4
CentiServer: A Comprehensive Resource, Web-Based Application and R Package for Centrality Analysis
Published in PloS one (16-11-2015)“…Various disciplines are trying to solve one of the most noteworthy queries and broadly used concepts in biology, essentiality. Centrality is a primary index…”
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Evolution of Centrality Measurements for the Detection of Essential Proteins in Biological Networks
Published in Frontiers in physiology (26-08-2016)Get full text
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Overexpression of Bromodomain and Extraterminal Domain is Associated with Progression, Metastasis and Unfavorable Outcomes: Highlighting Prognostic and Therapeutic Value of the BET Protein Family in Gastric Cancer
Published in Anti-cancer agents in medicinal chemistry (01-01-2023)“…As epigenetic readers, Bromodomain and extraterminal domain (BET) proteins have attracted immense interest in developing novel therapies targeting this family…”
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Metabolism of Arsenic Trioxide in Acute Promyelocytic Leukemia Cells
Published in Journal of cellular biochemistry (01-10-2014)“…Arsenic trioxide (As2O3) effectively induces complete clinical and molecular remissions in acute promyelocytic leukemia (APL) patients and triggers apoptosis…”
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Assessing the prognostic factors, survival, and recurrence incidence of triple negative breast cancer patients, a single center study in Iran
Published in PloS one (04-01-2019)“…Breast cancer is the second leading cause of death due to cancer in women. Triple negative breast cancer (TNBC) is a subgroup with unique behavior. There is a…”
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IL-6/IL-6R pathway is a therapeutic target in chemoresistant ovarian cancer
Published in Tumori (01-02-2019)“…Introduction: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy worldwide and despite an initial response to therapeutic agents, the…”
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PB2178: EVALUATION OF JAK2 EXON 12 MUTATIONS IN PATIENTS WITH JAK2 (V617F)‐NEGATIVE POLYCYTHEMIA VERA
Published in HemaSphere (08-08-2023)Get full text
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A fludarabine and melphalan reduced-intensity conditioning regimen for HSCT in fifteen chronic granulomatous disease patients and a literature review
Published in Annals of hematology (01-04-2022)“…Chronic granulomatous disease (CGD) is a life-threatening immunodeficiency condition. To date, hematopoietic stem cell transplantation (HSCT) is the only…”
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Synergistic Effects of Arsenic Trioxide and Silibinin on Apoptosis and Invasion in Human Glioblastoma U87MG Cell Line
Published in Neurochemical research (01-02-2012)“…Patients with glioblastoma multiforme (GBM) have poor therapeutic outcomes despite their current therapy. In an attempt to increase the efficacy of therapy for…”
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Expression Analysis of PVT1, CCDC26, and CCAT1 Long Noncoding RNAs in Acute Myeloid Leukemia Patients
Published in Genetic testing and molecular biomarkers (01-10-2018)“…Recent evidence indicates that the PVT1, CCDC26, and CCAT1 long noncoding RNAs (lncRNAs) are involved in the leukemogenic process. This study quantified the…”
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Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells
Published in Scientific reports (23-06-2017)“…Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy worldwide. Development of chemoresistance and peritoneal dissemination of EOC…”
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Correlation of HER2, MDM2, c-MYC, c-MET, and TP53 Copy Number Alterations in Circulating Tumor Cells with Tissue in Gastric Cancer Patients: A Pilot Study
Published in Iranian biomedical journal (2020)“…The analysis of the gene copy number alterations in tumor samples are increasingly used for diagnostic and prognostic purposes in patients with gastric cancer…”
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Demethylation and alterations in the expression level of the cell cycle–related genes as possible mechanisms in arsenic trioxide–induced cell cycle arrest in human breast cancer cells
Published in Tumor biology (01-02-2017)“…Arsenic trioxide (As2O3) has been used clinically as an anti-tumor agent. Its mechanisms are mostly considered to be the induction of apoptosis and cell cycle…”
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Altered expression of MALAT1 lncRNA in chronic lymphocytic leukemia patients, correlation with cytogenetic findings
Published in Blood research (01-12-2018)“…Recent studies have devoted much attention to non-protein-coding transcripts in relation to a wide range of malignancies. , a long non-coding RNA, has been…”
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Anti-tumor activity of cediranib, a pan-vascular endothelial growth factor receptor inhibitor, in pancreatic ductal adenocarcinoma cells
Published in Cellular oncology (Dordrecht) (01-02-2020)“…Purpose Pancreatic ductal adenocarcinoma (PDAC) is the most common and lethal subtype of pancreatic cancer, with a 5-year survival rate of < 3%. Early tumor…”
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A Comparison of Dexamethasone plus Vincristine versus Standard Regimen in Induction Therapy of Adult Acute Lymphoblastic Leukemia Patients Undergoing Hematopoietic Stem Cell Transplantation
Published in International journal of hematology- oncology and stem cell research (2022)“…Background: Current treatment options of acute lymphoblastic leukemia(ALL) include chemotherapy alone or hematopoietic stem cell transplantation (HSCT)…”
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Concurrent Evaluation of the Expression and Methylation of Secreted Frizzled-Related Protein 2 along with Beta-Catenin Expression in Patients with non-M3 Acute Myeloid Leukemia
Published in Iranian journal of medical sciences (01-05-2021)“…Background: Wnt signaling is a critical pathway for the development of acute myeloid leukemia (AML). Some studies have evaluated the expression or methylation…”
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