Search Results - "Aliev, Oleg I"
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Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats
Published in Molecules (Basel, Switzerland) (03-05-2019)“…c-Jun N-terminal kinase (JNK) is activated by various brain insults and is implicated in neuronal injury triggered by reperfusion-induced oxidative stress…”
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Antihypertensive activity of a new c-Jun N-terminal kinase inhibitor in spontaneously hypertensive rats
Published in Hypertension research (01-10-2020)“…c-Jun N-terminal kinases (JNKs) are involved in the myocardial and aortic remodeling, increased arterial tone, and arterial blood pressure elevation associated…”
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Neuroprotective Effects of Tryptanthrin-6-Oxime in a Rat Model of Transient Focal Cerebral Ischemia
Published in Pharmaceuticals (Basel, Switzerland) (25-07-2023)“…The activation of c-Jun N-terminal kinase (JNK) plays an important role in stroke outcomes. Tryptanthrin-6-oxime (TRYP-Ox) is reported to have high affinity…”
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Neuroprotective Effects of a Novel Inhibitor of c-Jun N-Terminal Kinase in the Rat Model of Transient Focal Cerebral Ischemia
Published in Cells (Basel, Switzerland) (08-08-2020)“…A novel specific inhibitor of c-Jun N-terminal kinase, 11 -indeno[1,2- ]quinoxalin-11-one oxime sodium salt (IQ-1S), has a high affinity to JNK3 compared to…”
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Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia–Reperfusion
Published in Biomedicines (29-08-2022)“…The c-Jun N-terminal kinases (JNKs) regulate many physiological processes, including inflammatory responses, morphogenesis, cell proliferation,…”
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Cardioprotective Effects of a Selective c-Jun N-terminal Kinase Inhibitor in a Rat Model of Myocardial Infarction
Published in Biomedicines (27-02-2023)“…Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial…”
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Effects of pentoxifylline on hemodynamic, hemorheological, and microcirculatory parameters in young SHRs during arterial hypertension development
Published in Clinical and experimental hypertension (1993) (18-08-2017)“…The most common form of hypertension in young adults is isolated diastolic hypertension. Diastolic arterial pressure is determined by the total peripheral…”
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An Improved Three-Vessel Occlusion Model of Global Cerebral Ischemia in Rats
Published in Brain research bulletin (01-06-2017)“…Graphical abstract…”
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Effect of p-tyrosol on hemorheological parameters and cerebral capillary network in young spontaneously hypertensive rats
Published in Microvascular research (01-09-2018)“…Many pathological mechanisms are involved in the development of arterial hypertension; disturbance of the rheological properties of blood and microvascular…”
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Pentoxifylline treatment enhances antihypertensive activity of captopril through hemorheological improvement in spontaneously hypertensive rats during development of arterial hypertension
Published in Journal of the American Society of Hypertension (01-11-2017)“…The rheological properties of blood play a significant role in the onset and progression of arterial hypertension. The aim of our work was to evaluate the…”
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Hemorheological effects of secoisolariciresinol in ovariectomized rats
Published in Biorheology (Oxford) (21-04-2016)“…Postmenopausal women often develop hemorheological disorders which may affect the systemic blood circulation and present a cardiovascular risk factor. We…”
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Relationship between arterial blood pressure and blood viscosity in spontaneously hypertensive rats treated with pentoxifylline
Published in Biorheology (Oxford) (12-08-2016)“…Systemic arterial pressure (AP) depends on two physiological variables: cardiac output (CO) and total peripheral resistance (TPR). The latter depends on…”
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Hemorheological effects of amlodipine in spontaneously hypertensive rats
Published in Indian journal of pharmacology (01-07-2017)“…The effect of course administration of amlodipine on whole blood viscosity and on macro- and microrheological parameters was evaluated. SHRs were treated…”
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Hemorheological parameters and their correlations in OXYS rats: a new model of hyperviscosity syndrome
Published in Clinical hemorheology and microcirculation (01-01-2015)“…Rheohaemapheresis aims to normalize major rheological parameters and is used to treat patients with dry age-related macular degeneration (AMD). While…”
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Pharmacological effects of a new soluble guanylate cyclase stimulator in experimental pulmonary arterial hypertension
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (01-01-2023)“…Aim. To assess the effect of an indolinone derivative (2-[2-[(5RS)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidine-2yliden]-2-cyanoethylidene]-1H-indole-3(2H)-one…”
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