Search Results - "Alicia Padilla"

Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells by López-Grueso, María José, Lagal, Daniel José, García-Jiménez, Álvaro Fernando, Tarradas, Rosa María, Carmona-Hidalgo, Beatriz, Peinado, José, Requejo-Aguilar, Raquel, Bárcena, José Antonio, Padilla, Carmen Alicia

“…Peroxiredoxin 6 (PRDX6) has been associated with tumor progression and cancer metastasis. Its acting on phospholipid hydroperoxides and its phospholipase-A2…”
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Real‐life study in non‐atopic severe asthma patients achieving disease control by omalizumab treatment by Campo, Paloma, Soto Campos, Gregorio, Moreira, Ana, Quirce, Santiago, Padilla‐Galo, Alicia, Martínez‐Moragón, Eva, Mardones, Aizea, Dávila, Ignacio

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Glutathione Is the Resolving Thiol for Thioredoxin Peroxidase Activity of 1-Cys Peroxiredoxin Without Being Consumed During the Catalytic Cycle by Pedrajas, José Rafael, McDonagh, Brian, Hernández-Torres, Francisco, Miranda-Vizuete, Antonio, González-Ojeda, Raúl, Martínez-Galisteo, Emilia, Padilla, C Alicia, Bárcena, José Antonio

“…A three-step catalytic cycle is common to all peroxiredoxins (Prxs), despite structural and kinetic differences. The second step in 1-Cys type Prxs is a matter…”
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Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer by Rodríguez-Hernández, María A., de la Cruz-Ojeda, P, López-Grueso, Mª José, Navarro-Villarán, Elena, Requejo-Aguilar, Raquel, Castejón-Vega, Beatriz, Negrete, María, Gallego, Paloma, Vega-Ochoa, Álvaro, Victor, Victor M., Cordero, Mario D., Del Campo, José A., Bárcena, J. Antonio, Padilla, C. Alicia, Muntané, Jordi

“…Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals, evasion of apoptosis, cellular stress, and sustained…”
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Determination of glutaredoxin enzyme activity and protein S-glutathionylation using fluorescent eosin-glutathione by Coppo, Lucia, Montano, Sergio J., Padilla, Alicia C., Holmgren, Arne

“…Glutaredoxins catalyze glutathione-dependent disulfide oxidoreductions, particularly reduction of glutathione (GSH)-protein mixed disulfides. Mammalian…”
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Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer by González, Raúl, Rodríguez-Hernández, María A., Negrete, María, Ranguelova, Kalina, Rossin, Aurelie, Choya-Foces, Carmen, Cruz-Ojeda, Patricia de la, Miranda-Vizuete, Antonio, Martínez-Ruiz, Antonio, Rius-Pérez, Sergio, Sastre, Juan, Bárcena, José A., Hueber, Anne-Odile, Padilla, C. Alicia, Muntané, Jordi

“…Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related…”
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Exploring the impact of maternal factors and dietary habits on human milk oligosaccharide composition in early breastfeeding among Mexican women by Urrutia-Baca, Víctor H., Gutiérrez-Uribe, Janet A., Ramos-Parra, Perla A., Domínguez-Uscanga, Astrid, Rodriguez-Gutierrez, Nora A., Chavez-Caraza, Karla L., Martinez-Cano, Ilen, Padilla-Garza, Alicia S., Ruiz-Villarreal, Elias G., Espiricueta-Candelaria, Francisca, Chuck-Hernández, Cristina

“…Human milk oligosaccharides (HMOs) promote adequate intestinal microbiota development and favor the immune system's maturation and cognitive development. In…”
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Rothmund-Thomson syndrome: a case series from a tertiary pediatric hospital in Mexico by Sánchez-Padilla, Alicia P, Valencia-Herrera, Adriana M, Toledo-Bahena, Mirna E, Mena-Cedillos, Carlos A, Toussaint-Caire, Sonia

“…Rothmund-Thomson syndrome, also known as congenital poikiloderma, is a rare autosomal recessive genodermatosis with onset in early childhood that affects at a…”
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Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells by López-Grueso, María José, González, Raúl, Muntané, Jordi, Bárcena, José Antonio, Padilla, C. Alicia

“…Sorafenib is the first-line recommended therapy for patients with advanced hepatocarcinoma (HCC) in de-differentiation stage (presenting epithelial–mesenchymal…”
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Asthma Control in Patients with Severe Eosinophilic Asthma Treated with Reslizumab: Spanish Real-Life Data by Pérez de Llano, Luis A, Cosío, Borja G, Lobato Astiárraga, Ignacio, Soto Campos, Gregorio, Tejedor Alonso, Miguel Ángel, Marina Malanda, Nuria, Padilla Galo, Alicia, Urrutia Landa, Isabel, Michel de la Rosa, Francisco J, García-Moguel, Ismael

“…Reslizumab is an anti-interleukin 5 monoclonal antibody that has demonstrated to reduce the risk of severe exacerbations and to improve symptoms, lung…”
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NOX1 and PRDX6 synergistically support migration and invasiveness of hepatocellular carcinoma cells through enhanced NADPH oxidase activity by Lagal, Daniel J., Bárcena, J. Antonio, Requejo-Aguilar, Raquel, Padilla, C. Alicia, Leto, Thomas L.

“…•NOX1 activity promotes hallmarks of metastasis including cell migration and invasion.•PRDX6 contributes to these pro-metastatic pathways through direct…”
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COVID-19 (SARS-CoV-2) lymphocyte responses are associated with inflammatory biomarkers in total joint replacement surgery candidates pre-operatively by Caicedo, Marco S, Flores, Vianey, Padilla, Alicia, Lauryn, Samelko, Jacobs, Joshua J, Hallab, Nadim J

“…Background Recent studies indicate that, in addition to antibody production, lymphocyte responses to SARS-CoV-2 may play an important role in protective…”
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Loss of PRDX6 Aborts Proliferative and Migratory Signaling in Hepatocarcinoma Cell Lines by Lagal, Daniel J, López-Grueso, María J, Pedrajas, José R, Leto, Thomas L, Bárcena, J Antonio, Requejo-Aguilar, Raquel, Padilla, C Alicia

“…Peroxiredoxin 6 (PRDX6), the only mammalian 1-Cys member of the peroxiredoxin family, has peroxidase, phospholipase A2 (PLA2), and lysophosphatidylcholine…”
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Deficiency of Parkinson’s Related Protein DJ-1 Alters Cdk5 Signalling and Induces Neuronal Death by Aberrant Cell Cycle Re-entry by López-Grueso, María José, Padilla, Carmen Alicia, Bárcena, José Antonio, Requejo-Aguilar, Raquel

“…DJ-1 is a multifunctional protein involved in Parkinson disease (PD) that can act as antioxidant, molecular chaperone, protease, glyoxalase, and…”
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Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells by González, Raúl, López-Grueso, M José, Muntané, Jordi, Bárcena, J Antonio, Padilla, C Alicia

“…Nitric oxide (NO) plays relevant roles in signal transduction in physiopathology and its effects are dependent on several environmental factors. NO has both…”
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Structural Aspects of the Distinct Biochemical Properties of Glutaredoxin 1 and Glutaredoxin 2 from Saccharomyces cerevisiae by Discola, Karen Fulan, de Oliveira, Marcos Antonio, Rosa Cussiol, José Renato, Monteiro, Gisele, Bárcena, José Antonio, Porras, Pablo, Padilla, C. Alicia, Guimarães, Beatriz Gomes, Netto, Luis Eduardo Soares

“…Glutaredoxins (Grxs) are small (9–12 kDa) heat-stable proteins that are ubiquitously distributed. In Saccharomyces cerevisiae, seven Grx enzymes have been…”
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Peroxiredoxin 6 Down-Regulation Induces Metabolic Remodeling and Cell Cycle Arrest in HepG2 Cells by López Grueso, María José, Tarradas Valero, Rosa María, Carmona-Hidalgo, Beatriz, Lagal Ruiz, Daniel José, Peinado, José, McDonagh, Brian, Requejo Aguilar, Raquel, Bárcena Ruiz, José Antonio, Padilla Peña, Carmen Alicia

“…Peroxiredoxin 6 (Prdx6) is the only member of 1-Cys subfamily of peroxiredoxins in human cells. It is the only Prdx acting on phospholipid hydroperoxides…”
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Glutaredoxin participates in the reduction of peroxides by the mitochondrial 1-CYS peroxiredoxin in Saccharomyces cerevisiae by Pedrajas, José Rafael, Padilla, C Alicia, McDonagh, Brian, Bárcena, José Antonio

“…The mechanism for regeneration of the active-site "peroxidatic" cysteine in 1-Cys peroxiredoxins is a matter of debate. Saccharomyces cerevisiae Prx1 is a…”
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Biosynthetic and Iron Metabolism Is Regulated by Thiol Proteome Changes Dependent on Glutaredoxin-2 and Mitochondrial Peroxiredoxin-1 in Saccharomyces cerevisiae by McDonagh, Brian, Padilla, C. Alicia, Pedrajas, José Rafael, Bárcena, José Antonio

“…Redoxins are involved in maintenance of thiol redox homeostasis, but their exact sites of action are only partly known. We have applied a combined redox…”
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Impact of reslizumab on outcomes of severe asthmatic patients: current perspectives by Padilla Galo, Alicia, Labor, Marina, Tiotiu, Angelica, Baiardini, Ilaria, Scichilone, Nicola, Braido, Fulvio

“…Approximately 5%-10% of asthmatics suffer from severe asthma. New biological treatments represent a great opportunity to reduce asthma burden and to improve…”
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