Search Results - "Alice, Bertocchi"

A gut-vascular barrier controls the systemic dissemination of bacteria by Spadoni, Ilaria, Zagato, Elena, Bertocchi, Alice, Paolinelli, Roberta, Hot, Edina, Di Sabatino, Antonio, Caprioli, Flavio, Bottiglieri, Luca, Oldani, Amanda, Viale, Giuseppe, Penna, Giuseppe, Dejana, Elisabetta, Rescigno, Maria

“…In healthy individuals, the intestinal microbiota cannot access the liver, spleen, or other peripheral tissues. Some pathogenic bacteria can reach these sites,…”
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Identification of a choroid plexus vascular barrier closing during intestinal inflammation by Carloni, Sara, Bertocchi, Alice, Mancinelli, Sara, Bellini, Martina, Erreni, Marco, Borreca, Antonella, Braga, Daniele, Giugliano, Silvia, Mozzarelli, Alessandro M, Manganaro, Daria, Fernandez Perez, Daniel, Colombo, Federico, Di Sabatino, Antonio, Pasini, Diego, Penna, Giuseppe, Matteoli, Michela, Lodato, Simona, Rescigno, Maria

“…Up to 40% of patients with inflammatory bowel disease present with psychosocial disturbances. We previously identified a gut vascular barrier that controls the…”
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Extrafollicular IgD−CD27−CXCR5−CD11c− DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19 by Allard-Chamard, Hugues, Kaneko, Naoki, Bertocchi, Alice, Sun, Na, Boucau, Julie, Kuo, Hsiao-Hsuan, Farmer, Jocelyn R., Perugino, Cory, Mahajan, Vinay S., Murphy, Samuel J.H., Premo, Katherine, Diefenbach, Thomas, Ghebremichael, Musie, Yuen, Grace, Kotta, Alekhya, Akman, Zafer, Lichterfeld, Mathias, Walker, Bruce D., Yu, Xu G., Moriyama, Masafumi, Maehara, Takashi, Nakamura, Seiji, Stone, John H., Padera, Robert F., Pillai, Shiv

“…Although therapeutic B cell depletion dramatically resolves inflammation in many diseases in which antibodies appear not to play a central role, distinct…”
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A viral cocktail calms gut inflammation by Bertocchi, Alice, Powrie, Fiona

“…Abnormalities in gut bacteria can contribute to hard-to-treat illnesses, such as inflammatory bowel diseases. Efforts to harness bacterium-targeting viruses…”
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IL-3 finds its home in the brain by Bertocchi, Alice, Dougan, Stephanie K.

“…Interleukin-3 (IL-3) induces emergency hematopoiesis in settings of acute inflammation. In this issue of Immunity, Kiss et al. find that IL-3 derived from…”
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Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver by Bertocchi, Alice, Carloni, Sara, Ravenda, Paola Simona, Bertalot, Giovanni, Spadoni, Ilaria, Lo Cascio, Antonino, Gandini, Sara, Lizier, Michela, Braga, Daniele, Asnicar, Francesco, Segata, Nicola, Klaver, Chris, Brescia, Paola, Rossi, Elio, Anselmo, Achille, Guglietta, Silvia, Maroli, Annalisa, Spaggiari, Paola, Tarazona, Noelia, Cervantes, Andres, Marsoni, Silvia, Lazzari, Luca, Jodice, Maria Giovanna, Luise, Chiara, Erreni, Marco, Pece, Salvatore, Di Fiore, Pier Paolo, Viale, Giuseppe, Spinelli, Antonino, Pozzi, Chiara, Penna, Giuseppe, Rescigno, Maria

“…Metastasis is facilitated by the formation of a “premetastatic niche,” which is fostered by primary tumor-derived factors. Colorectal cancer (CRC) metastasizes…”
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Immune microniches shape intestinal Treg function by Gu, Yisu, Bartolomé-Casado, Raquel, Xu, Chuan, Bertocchi, Alice, Janney, Alina, Heuberger, Cornelia, Pearson, Claire F., Teichmann, Sarah A., Thornton, Emily E., Powrie, Fiona

“…The intestinal immune system is highly adapted to maintaining tolerance to the commensal microbiota and self-antigens while defending against invading…”
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Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth by Zagato, Elena, Pozzi, Chiara, Bertocchi, Alice, Schioppa, Tiziana, Saccheri, Fabiana, Guglietta, Silvia, Fosso, Bruno, Melocchi, Laura, Nizzoli, Giulia, Troisi, Jacopo, Marzano, Marinella, Oresta, Bianca, Spadoni, Ilaria, Atarashi, Koji, Carloni, Sara, Arioli, Stefania, Fornasa, Giulia, Asnicar, Francesco, Segata, Nicola, Guglielmetti, Simone, Honda, Kenya, Pesole, Graziano, Vermi, William, Penna, Giuseppe, Rescigno, Maria

“…The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-tumourigenic effect has also been postulated. Here, we demonstrate that…”
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MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T-cell responses by Heuberger, Cornelia E., Janney, Alina, Ilott, Nicholas, Bertocchi, Alice, Pott, Sebastian, Gu, Yisu, Pohin, Mathilde, Friedrich, Matthias, Mann, Elizabeth H., Pearson, Claire, Powrie, Fiona M., Pott, Johanna, Thornton, Emily, Maloy, Kevin Joseph

“…Although intestinal epithelial cells (IECs) can express major histocompatibility complex class II (MHC II), especially during intestinal inflammation, it…”
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Abstract A024: B cells facilitate lymph node colonization in pancreatic ductal adenocarcinoma by Bertocchi, Alice, Hoffman, Megan T., Qiang, Li, Hsu, Lauren, Dougan, Michael, Agudo, Judith, Dougan, Stephanie K.

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) has a low survival rate. Several factors contribute to its dismal prognosis, including resistance to available…”
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Induction of metabolic quiescence defines the transitional to follicular B cell switch by Farmer, Jocelyn R, Allard-Chamard, Hugues, Sun, Na, Ahmad, Maimuna, Bertocchi, Alice, Mahajan, Vinay S, Aicher, Toby, Arnold, Johan, Benson, Mark D, Morningstar, Jordan, Barmettler, Sara, Yuen, Grace, Murphy, Samuel J H, Walter, Jolan E, Ghebremichael, Musie, Shalek, Alex K, Batista, Facundo, Gerszten, Robert, Pillai, Shiv

“…Transitional B cells must actively undergo selection for self-tolerance before maturing into their resting follicular B cell successors. We found that…”
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Abstract B040: B cells facilitate lymph node colonization in pancreatic ductal adenocarcinoma by Bertocchi, Alice, Hoffman, Megan T, Qiang, Li, Morell, Massiel, Hsu, Lauren L, Dougan, Michael L, Agudo, Judith, Dougan, Stephanie K

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) carries a low survival rate. Several factors contribute to its dismal prognosis, including resistance to…”
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BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection? by Darwich, Abbass, Pozzi, Chiara, Fornasa, Giulia, Lizier, Michela, Azzolini, Elena, Spadoni, Ilaria, Carli, Francesco, Voza, Antonio, Desai, Antonio, Ferrero, Carlo, Germagnoli, Luca, Mantovani, Alberto, Rescigno, Maria, Alessio, Aghemo, Clement, Anfray, Salvatore, Badalamenti, Cristina, Belgiovine, Alice, Bertocchi, Sara, Bombace, Paola, Brescia, Francesca, Calcaterra, Michela, Calvi, Assunta, Cancellara, Arianna, Capucetti, Claudia, Carenza, Sara, Carloni, Silvia, Carnevale, Valentina, Cazzetta, Maurizio, Cecconi, Michele, Ciccarelli, Nicolò, Coianiz, Abbass, Darwich, Lleo De Nalda, Ana, Federica, De Paoli, Rachele, Di Donato, Elisabeth, Digifico, Barbara, Durante, Maria, Farina Floriana, Valentina, Ferrari, Giulia, Fornasa, Sara, Franzese, Antonio, Gil Gomez, Silvia, Giugliano, Gomes, Ana Rita, Michela, Lizier, Antonino, Lo Cascio, Alessia, Melacarne, Alessandro, Mozzarelli, Ilaria, My, Bianca, Oresta, Fabio, Pasqualini, Anna, Pastò, Erica, Pelamatti, Chiara, Perucchini, Chiara, Pozzi, Valeria, Rimoldi, Monica, Rimoldi, Alice, Scarpa, Carlo, Selmi, Alessandra, Silvestri, Marina, Sironi, Ilaria, Spadoni, Salvatore, Spano', Gianmarco, Spata, Domenico, Supino, Paolo, Tentorio, Aldo, Ummarino, Sonia, Valentino, Antonio, Voza, Elisa, Zaghi, Veronica, Zanon

“…Vaccination against an airborne pathogen is very effective if it induces also the development of mucosal antibodies that can protect against infection. The…”
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9-O-acetyl sialic acid levels identify committed progenitors of plasmacytoid dendritic cells by Netravali, Ilka A, Cariappa, Annaiah, Yates, Kathleen, Haining, W Nicholas, Bertocchi, Alice, Allard-Chamard, Hugues, Rosenberg, Ian, Pillai, Shiv

“…The origins of plasmacytoid dendritic cells (pDCs) have long been controversial and progenitors exclusively committed to this lineage have not been described…”
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Immune microniches shape intestinal T reg function by Gu, Yisu, Bartolomé-Casado, Raquel, Xu, Chuan, Bertocchi, Alice, Janney, Alina, Heuberger, Cornelia, Pearson, Claire F, Teichmann, Sarah A, Thornton, Emily E, Powrie, Fiona

“…The intestinal immune system is highly adapted to maintaining tolerance to the commensal microbiota and self-antigens while defending against invading…”
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Abstract B065: Eosinophils alter metastatic spread in pancreatic cancer by Hoffman, Megan T, Lenehan, Patrick J, Bertocchi, Alice, Wang, Jen, Ali, Lestat, Qiang, Li, Uchida, Amiko, Vayrynen, Sara, Costa, Andressa Dias, Dougan, Michael, Heckler, Max, Nowak, Jonathan, Wolpin, Brian W, Dougan, Stephanie K

“…Abstract Pancreatic ductal adenocarcinoma (PDA) is the third most common cause of cancer death in the US with a 11% 5-year survival rate. A key contributor of…”
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MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T-cell responses by Heuberger, Cornelia E, Janney, Alina, Ilott, Nicholas, Bertocchi, Alice, Pott, Sebastian, Gu, Yisu, Pohin, Mathilde, Friedrich, Matthias, Mann, Elizabeth H, Pearson, Claire, Powrie, Fiona M, Pott, Johanna, Thornton, Emily, Maloy, Kevin Joseph

“…Although intestinal epithelial cells (IECs) can express major histocompatibility complex class II (MHC II), especially during intestinal inflammation, it…”
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Mucosa-associated microbiota drives pathogenic functions in IBD-derived intestinal iNKT cells by Burrello, Claudia, Pellegrino, Gabriella, Giuffrè, Maria Rita, Lovati, Giulia, Magagna, Ilaria, Bertocchi, Alice, Cribiù, Fulvia Milena, Boggio, Francesca, Botti, Fiorenzo, Trombetta, Elena, Porretti, Laura, Di Sabatino, Antonio, Vecchi, Maurizio, Rescigno, Maria, Caprioli, Flavio, Facciotti, Federica

“…Inflammatory bowel disease (IBD) pathogenesis has been linked to the aberrant activation of the Gut-associated lymphoid tissues against components of the…”
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A ‘Multiomic’ Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019 by Pozzi, Chiara, Levi, Riccardo, Braga, Daniele, Carli, Francesco, Darwich, Abbass, Spadoni, Ilaria, Oresta, Bianca, Dioguardi, Carola Conca, Peano, Clelia, Ubaldi, Leonardo, Angelotti, Giovanni, Bottazzi, Barbara, Garlanda, Cecilia, Desai, Antonio, Voza, Antonio, Azzolini, Elena, Cecconi, Maurizio, Alessio, Aghemo, Clement, Anfray, Salvatore, Badalamenti, Cristina, Belgiovine, Alice, Bertocchi, Sara, Bombace, Paola, Brescia, Francesca, Calcaterra, Michela, Calvi, Assunta, Cancellara, Arianna, Capucetti, Claudia, Carenza, Sara, Carloni, Silvia, Carnevale, Valentina, Cazzetta, Maurizio, Cecconi, Michele, Ciccarelli, Nicolò, Coianiz, Abbass, Darwich, de Nalda Ana, Lleo, Federica, De Paoli, Rachele, Di Donato, Elisabeth, Digifico, Barbara, Durante, Maria, FARINA Floriana, Valentina, Ferrari, Giulia, Fornasa, Sara, Franzese, Antonio, Gil Gomez, Silvia, Giugliano, Rita, Gomes Ana, Michela, Lizier, Antonino, Lo Cascio, Alessia, Melacarne, Alessandro, Mozzarelli, Ilaria, My, Bianca, Oresta, Fabio, Pasqualini, Anna, Pastò, Erica, Pelamatti, Chiara, Perucchini, Chiara, Pozzi, Valeria, Rimoldi, Monica, Rimoldi, Alice, Scarpa, Carlo, Selmi, Alessandra, Silvestri, Marina, Sironi, Ilaria, Spadoni, Salvatore, Spano', Gianmarco, Spata, Domenico, Supino, Paolo, Tentorio, Aldo, Ummarino, Sonia, Valentino, Antonio, Voza, Elisa, Zaghi, Veronica, Zanon, Mantovani, Alberto, Penna, Giuseppe, Barbieri, Riccardo, Politi, Letterio S., Rescigno, Maria

“…The SARS-CoV-2 pandemic has overwhelmed the treatment capacity of the health care systems during the highest viral diffusion rate. Patients reaching the…”
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BNT162b2 vaccine induces antibody release in saliva: a possible role for mucosal viral protection? by Darwich, Abbass, Pozzi, Chiara, Fornasa, Giulia, Lizier, Michela, Azzolini, Elena, Spadoni, Ilaria, Carli, Francesco, Voza, Antonio, Desai, Antonio, Ferrero, Carlo, Germagnoli, Luca, Mantovani, Alberto, Rescigno, Maria, Alessio, Aghemo, Clement, Anfray, Salvatore, Badalamenti, Cristina, Belgiovine, Alice, Bertocchi, Sara, Bombace, Paola, Brescia, Francesca, Calcaterra, Michela, Calvi, Assunta, Cancellara, Arianna, Capucetti, Claudia, Carenza, Sara, Carloni, Silvia, Carnevale, Valentina, Cazzetta, Maurizio, Cecconi, Michele, Ciccarelli, Nicolò, Coianiz, Abbass, Darwich, Lleo De Nalda, Ana, Federica, De Paoli, Rachele, Di Donato, Elisabeth, Digifico, Barbara, Durante, Maria, Farina Floriana, Valentina, Ferrari, Giulia, Fornasa, Sara, Franzese, Antonio, Gil Gomez, Silvia, Giugliano, Gomes, Ana Rita, Michela, Lizier, Antonino, Lo Cascio, Alessia, Melacarne, Alessandro, Mozzarelli, Ilaria, My, Bianca, Oresta, Fabio, Pasqualini, Anna, Pastò, Erica, Pelamatti, Chiara, Perucchini, Chiara, Pozzi, Valeria, Rimoldi, Monica, Rimoldi, Alice, Scarpa, Carlo, Selmi, Alessandra, Silvestri, Marina, Sironi, Ilaria, Spadoni, Salvatore, Spano', Gianmarco, Spata, Domenico, Supino, Paolo, Tentorio, Aldo, Ummarino, Sonia, Valentino, Antonio, Voza, Elisa, Zaghi, Veronica, Zanon

“…Vaccination against an airborne pathogen is very effective if it induces also the development of mucosal antibodies that can protect against infection. The…”
Get full text