Search Results - "Ali Shati"

Doxorubicin‐induces NFAT/Fas/FasL cardiac apoptosis in rats through activation of calcineurin and P38 MAPK and inhibition of mTOR signalling pathways by Shati, Ali A.

“…This study investigated the role of NFAT/Fas/FasL axis in cardiomyocyte apoptosis following doxorubicin (DOX) treatment in rats and evaluated the involvement…”
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Resveratrol protects against cadmium chloride‐induced hippocampal neurotoxicity by inhibiting ER stress and GAAD 153 and activating sirtuin 1/AMPK/Akt by Shati, Ali A.

“…This study investigated whether the apoptotic effect induced by cadmium chloride (CdCl2) in rat's hippocampi and neuroprotection afforded by resveratrol (RES)…”
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Resveratrol improves sperm parameter and testicular apoptosis in cisplatin-treated rats: Effects on ERK1/2, JNK, and Akt pathways by Shati, Ali A.

“…This study aimed to investigate the protective role of resveratrol (RES) against cisplatin (Cis)-induced testicular damage and reproductive dysfunction in rats…”
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Salidroside ameliorates diabetic nephropathy in rats by activating renal AMPK/SIRT1 signaling pathway by Shati, Ali A.

“…This study investigated if the nephroprotective effect of Salidroside T1DM rats involves activation of AMPK/SIRT1. Rats were divided into control or T1DM and…”
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Recyclization of morpholinochromonylidene-thiazolidinone using nucleophiles: facile synthesis, cytotoxic evaluation, apoptosis, cell cycle and molecular docking studies of a novel series of azole, azine, azepine and pyran derivatives by Ali, Tarik E, Assiri, Mohammed A, Alqahtani, Maha N, Shati, Ali. A, Alfaifi, Mohammad. Y, Elbehairi, Serag. E. I

“…A convenient synthetic approach for construction of a novel series of substituted azoles, azines, azepines and pyrans clubbed with a morpholinothiazolidinone…”
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Acylated ghrelin suppresses doxorubicin-induced testicular damage and improves sperm parameters in rats via activation of Nrf2 and mammalian target of rapamycin by Shati, Ali, Khalil, Mohammad

“…Background: Exogenous administration of acylated ghrelin (AG) afforded reproductive protective effect in several animal models but not in those treated with…”
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Synthesis, In Vitro Antimicrobial and Cytotoxic Activities of Some New Pyrazolo[1,5- a ]pyrimidine Derivatives by Fouda, Ahmed M, Abbas, Hebat-Allah S, Ahmed, Eman H, Shati, Ali A, Alfaifi, Mohammad Y, Elbehairi, Serag Eldin I

“…A new series of pyrazole ⁻ and pyrazolo[1,5- ]pyrimidine ⁻ were synthesized by using a simple, efficient procedure, and screened for their in-vitro…”
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Development of novel kinetic model based on microbiome and biochar for in-situ remediation of total petroleum hydrocarbons (TPHs) contaminated soil by Saeed, Maimona, Ilyas, Noshin, Bibi, Fatima, Shabir, Sumera, Jayachandran, Krish, Sayyed, R.Z., Shati, Ali A., Alfaifi, Mohammad Y., Show, Pau Loke, Rizvi, Zarrin Fatima

“…A novel kinetic model has been developed to explain the degradation of total petroleum hydrocarbons. Microbiome engineered biochar amendment may result in a…”
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Cold-Active Enzymes and Their Potential Industrial Applications—A Review by Hamid, Burhan, Bashir, Zaffar, Yatoo, Ali Mohd, Mohiddin, Fayaz, Majeed, Neesa, Bansal, Monika, Poczai, Peter, Almalki, Waleed Hassan, Sayyed, R. Z., Shati, Ali A., Alfaifi, Mohammad Y.

“…More than 70% of our planet is covered by extremely cold environments, nourishing a broad diversity of microbial life. Temperature is the most significant…”
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Patterns and drivers of vector-borne microparasites in a classic metapopulation by Mackenzie, Laura S., Lambin, Xavier, Bryce, Emma, Davies, Claire L., Hassall, Richard, Shati, Ali A. M., Sutherland, Chris, Telfer, Sandra E.

“…Many organisms live in fragmented populations, which has profound consequences on the dynamics of associated parasites. Metapopulation theory offers a…”
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Protective effects of thymoquinone and diallyl sulphide against malathion-induced toxicity in rats by Abdel-Daim, Mohamed M., Abushouk, Abdelrahman Ibrahim, Bungău, Simona G., Bin-Jumah, May, El-kott, Attalla F., Shati, Ali A., Aleya, Lotfi, Alkahtani, Saad

“…Malathion is a potent organophosphate insecticide that inhibits acetylcholinesterase (AChE) enzyme. Our experimental objective was to investigate the…”
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Secondary metabolites of Trichoderma spp. as EGFR tyrosine kinase inhibitors: Evaluation of anticancer efficacy through computational approach by Gowtham, H G, Revanasiddappa, Prasanna D, Murali, Mahadevamurthy, Singh, Sudarshana Brijesh, Abhilash, M R, Pradeep, Sushma, Shivamallu, Chandan, Achar, Raghu Ram, Silina, Ekaterina, Stupin, Victor, Manturova, Natalia, Shati, Ali A, Alfaifi, Mohammad Y, Elbehairi, Serag Eldin I, Kollur, Shiva Prasad

“…The present study explores the epidermal growth factor receptor (EGFR) tyrosine kinase inhibition efficacy of secondary metabolites in Trichoderma spp. through…”
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Resolvin D1 protects against cadmium chloride-induced memory loss and hippocampal damage in rats: A comparison with docosahexaenoic acid by Shati, Ali A, El-Kott, Attalla F

“…Intoxication with cadmium (Cd) ions leads to hippocampal damage and cognitive impairment. However, omega-3 polyunsaturated fatty acids (n-3 PUFAs) exert…”
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Calycosin induces apoptosis in adenocarcinoma HT29 cells by inducing cytotoxic autophagy mediated by SIRT1/AMPK‐induced inhibition of Akt/mTOR by El‐kott, Attalla Farag, Al‐kahtani, Mohammed Ali, Shati, Ali A.

“…Autophagy promotes cell survival or induces apoptosis in cancer cells. While SIRT1 and AMPK induce autophagy in both normal and cancer cells, Akt and mTOR can…”
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Salidroside protects against diabetes mellitus‐induced kidney injury and renal fibrosis by attenuating TGF‐β1 and Wnt1/3a/β‐catenin signalling by Shati, Ali A., Alfaifi, Mohammad Y.

“…This study evaluated if the nephroprotective effect of Salidroside in type 1 diabetes mellitus (T1DM) involves modulation of Wnt/β‐catenin signalling pathways…”
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Exploration of CviR-mediated quorum sensing inhibitors from Cladosporium spp. against Chromobacterium violaceum through computational studies by Murali, Mahadevamurthy, Ahmed, Faiyaz, Gowtham, Hittanahallikoppal Gajendramurthy, Aribisala, Jamiu Olaseni, Abdulsalam, Rukayat Abiola, Shati, Ali A., Alfaifi, Mohammad Y., Sayyed, R. Z., Sabiu, Saheed, Amruthesh, Kestur Nagaraj

“…An opportunistic human pathogenic bacterium, Chromobacterium violaceum resists the potency of most antibiotics by exploiting the quorum sensing system within…”
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Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1 by Shati, Ali A., El-kott, Attalla Farag

“…This study investigated if JAK/STAT signaling pathway mediates doxorubicin (DOX)-induced cell death and fibrosis in left ventricles (LVs) of rats and examined…”
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Innovative production of value-added products using agro-industrial wastes via solid-state fermentation by Bibi, Fatima, Ilyas, Noshin, Saeed, Maimona, Shabir, Sumera, Shati, Ali A., Alfaifi, Mohammad Y., Amesho, Kassian T.T., Chowdhury, Subrata, Sayyed, Riyazali Zafarali

“…The prevalence of organic solid waste worldwide has turned into a problem that requires comprehensive treatment on all fronts. The amount of agricultural waste…”
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Exploration of Type III effector Xanthomonas outer protein Q (XopQ) inhibitor from Picrasma quassioides as an antibacterial agent using chemoinformatics analysis by Revanasiddappa, Prasanna D, Gowtham, H G, G S, Chikkanna, Gangadhar, Suchithra, A, Satish, Murali, M, Shivamallu, Chandan, Achar, Raghu Ram, Silina, Ekaterina, Stupin, Victor, Manturova, Natalia, Shati, Ali A, Alfaifi, Mohammad Y, Elbehairi, Serag Eldin I, Kollur, Shiva Prasad, Amruthesh, Kestur Nagaraj

“…The present study was focused on exploring the efficient inhibitors of closed state (form) of type III effector Xanthomonas outer protein Q (XopQ) (PDB: 4P5F)…”
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Acylated Ghrelin Protects the Hearts of Rats from Doxorubicin-Induced Fas/FasL Apoptosis by Stimulating SERCA2a Mediated by Activation of PKA and Akt by Shati, Ali A., Dallak, M.

“…This study investigated if the cardioprotective effect of acylated ghrelin (AG) against doxorubicin (DOX)-induced cardiac toxicity in rats involves inhibition…”
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