Search Results - "Ali Shah, Syed Zahid"

Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease by Zaplatic, Elizabeta, Bule, Muhammed, Shah, Syed Zahid Ali, Uddin, Md. Sahab, Niaz, Kamal

“…Quercetin belongs to the flavonoids family, which is present in most of the plants including fruits, vegetables, green tea and even in red wine having…”
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Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos by ULLAH, Obaid, LI, Zhongshu, ALI, Ihsan, XU, Lijie, LIU, Haixing, SHAH, Syed Zahid Ali, FANG, Nanzhu

“…Pterostilbene (PTS) in blueberries is a phytoalexin with antioxidant properties. PTS exerts strong cytoprotective effects on various cells via Nuclear Factor…”
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The Role of the Gut Microbiota in the Pathogenesis of Parkinson's Disease by Yang, Dongming, Zhao, Deming, Ali Shah, Syed Zahid, Wu, Wei, Lai, Mengyu, Zhang, Xixi, Li, Jie, Guan, Zhiling, Zhao, Huafen, Li, Wen, Gao, Hongli, Zhou, Xiangmei, Yang, Lifeng

“…It is well-recognized that the gut microbiota (GM) is crucial for gut function, metabolism, and energy cycles. The GM also has effects on neurological outcomes…”
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The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia by Lai, Mengyu, Yao, Hao, Shah, Syed Zahid Ali, Wu, Wei, Wang, Di, Zhao, Ying, Wang, Lu, Zhou, Xiangmei, Zhao, Deming, Yang, Lifeng

“…Prion diseases are neurodegenerative disorders characterized by the accumulation of misfolded prion protein, spongiform changes in the brain, and brain…”
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Phytochemical Screening, Anti-Inflammatory, and Antidiabetic Activities of Different Extracts from Caralluma edulis Plant by Khan, Maria, Manzoor, Zahid, Rafiq, Muhammad, Munawar, Shaukat Hussain, Waqas, Muhammad Yasir, Majeed, Hamid, Ali Shah, Syed Zahid, Hussain, Riaz, Hussain, Hafiz Iftikhar, Tahir, Tehreem, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…The plant Caralluma edulis is traditionally used against diabetes and inflammatory conditions in Pakistan. This study was designed to provide scientific…”
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Regulatory Mechanisms of Endoplasmic Reticulum Resident IP3 Receptors by Shah, Syed Zahid Ali, Zhao, Deming, Khan, Sher Hayat, Yang, Lifeng

“…Dysregulated calcium signaling and accumulation of aberrant proteins causing endoplasmic reticulum stress are the early sign of intra-axonal pathological…”
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Nexus among the perceived infrastructural, social, economic, and environmental impact of CPEC: A case of Pakistan by Anwar, Syed Umair, Yuan, Peng Zhi, Wuyi, Zhang, Amir, Syed Muhammad, Rehman, Shafique Ur, Yang, Lifan, Ali Shah, Syed Zahid

“…Despite its ambitious “economic sustainability” objectives, the China-Pakistan Economic Corridor (CPEC) has been the subject of growing environmental anxiety…”
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Pterostilbene alleviates hydrogen peroxide-induced oxidative stress via nuclear factor erythroid 2 like 2 pathway in mouse preimplantation embryos by ULLAH, Obaid, LI, Zhongshu, ALI, Ihsan, XU, Lijie, LIU, Haixing, SHAH, Syed Zahid Ali, FANG, Nanzhu

“…Pterostilbene (PTS) in blueberries is a phytoalexin with antioxidant properties. PTS exerts strong cytoprotective effects on various cells via Nuclear Factor…”
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Insight into TLR4 receptor inhibitory activity via QSAR for the treatment of Mycoplasma pneumonia disease by Zhu, Zemin, Rahman, Ziaur, Aamir, Muhammad, Shah, Syed Zahid Ali, Hamid, Sattar, Bilawal, Akhunzada, Li, Sihong, Ishfaq, Muhammad

“…(MP) is one of the most common pathogenic organisms causing upper and lower respiratory tract infections, lung injury, and even death in young children…”
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A central role for calcineurin in protein misfolding neurodegenerative diseases by Shah, Syed Zahid Ali, Hussain, Tariq, Zhao, Deming, Yang, Lifeng

“…Accumulation of misfolded/unfolded aggregated proteins in the brain is a hallmark of many neurodegenerative diseases affecting humans and animals…”
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miRNAs in Tuberculosis: New Avenues for Diagnosis and Host-Directed Therapy by Sabir, Naveed, Hussain, Tariq, Shah, Syed Zahid Ali, Peramo, Antonio, Zhao, Deming, Zhou, Xiangmei

“…Tuberculosis (TB) is one of the most fatal infectious diseases and a leading cause of mortality, with 95% of these deaths occurring in developing countries…”
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Ochratoxin A–induced genotoxic and epigenetic mechanisms lead to Alzheimer disease: its modulation with strategies by Niaz, Kamal, Shah, Syed Zahid Ali, Khan, Fazlullah, Bule, Mohammed

“…Ochratoxin A (OTA) is a naturally occurring mycotoxin mostly found in food items including grains and coffee beans. It induces DNA single-strand breaks and has…”
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DLP1‐dependent mitochondrial fragmentation and redistribution mediate prion‐associated mitochondrial dysfunction and neuronal death by Li, Chaosi, Wang, Di, Wu, Wei, Yang, Wei, Ali Shah, Syed Zahid, Zhao, Ying, Duan, Yuhan, Wang, Lu, Zhou, Xiangmei, Zhao, Deming, Yang, Lifeng

“…Summary Mitochondrial malfunction is a universal and critical step in the pathogenesis of many neurodegenerative diseases including prion diseases…”
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Implications of gut microbiota dysbiosis and metabolic changes in prion disease by Yang, Dongming, Zhao, Deming, Shah, Syed Zahid Ali, Wu, Wei, Lai, Mengyu, Zhang, Xixi, Li, Jie, Guan, Zhiling, Zhao, Huafen, Li, Wen, Gao, Hongli, Zhou, Xiangmei, Yang, Lifeng

“…Evidence of the gut microbiota influencing neurodegenerative diseases has been reported for several neural diseases. However, there is little insight regarding…”
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p62-Keap1-NRF2-ARE Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases by Shah, Syed Zahid Ali, Zhao, Deming, Hussain, Tariq, Sabir, Naveed, Mangi, Mazhar Hussain, Yang, Lifeng

“…Prion diseases are a group of fatal and debilitating neurodegenerative diseases affecting humans and animal species. The conversion of a non-pathogenic normal…”
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Unfolded Protein Response Pathways in Neurodegenerative Diseases by Shah, Syed Zahid Ali, Zhao, Deming, Khan, Sher Hayat, Yang, Lifeng

“…The aggregation of disease-specific misfolded proteins resulting in endoplasmic reticulum stress is associated with early pathological events in many…”
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OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases by Wu, Wei, Zhao, Deming, Shah, Syed Zahid Ali, Zhang, Xixi, Lai, Mengyu, Yang, Dongming, Wu, Xiaoqian, Guan, Zhiling, Li, Jie, Zhao, Huafen, Li, Wen, Gao, Hongli, Zhou, Xiangmei, Qiao, Jian, Yang, Lifeng

“…Prion diseases caused by the cellular prion protein (PrP C ) conversion into a misfolded isoform (PrP Sc ) are associated with multiple mitochondrial damages…”
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Proteome Analysis of Potential Synaptic Vesicle Cycle Biomarkers in the Cerebrospinal Fluid of Patients with Sporadic Creutzfeldt–Jakob Disease by Wang, Chunyu, Zhao, Deming, Shah, Syed Zahid Ali, Yang, Wei, Li, Chaosi, Yang, Lifeng

“…Sporadic Creutzfeldt–Jakob disease (sCJD) is the most frequent fatal human prion disease with a rapid progression and unknown mechanism. The synaptic vesicle…”
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Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases by Zhang, Xixi, Zhao, Deming, Wu, Wei, Ali Shah, Syed Zahid, Lai, Mengyu, Yang, Dongming, Li, Jie, Guan, Zhiling, Li, Wen, Gao, Hongli, Zhao, Huafen, Zhou, Xiangmei, Yang, Lifeng

“…Prion diseases are neurodegenerative diseases associated with neuron damage and behavioral disorders in animals and humans. Melatonin is a potent antioxidant…”
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The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases by Shah, Syed Zahid Ali, Zhao, Deming, Hussain, Tariq, Yang, Lifeng

“…Prion diseases are neurodegenerative pathologies characterized by the accumulation of a protease-resistant form of the cellular prion protein named prion…”
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