Search Results - "Ali Azouaou, Sarah"
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Selective ROS-dependent p53-associated anticancer effects of the hypoxoside derivative rooperol on human teratocarcinomal cancer stem-like cells
Published in Investigational new drugs (01-02-2015)“…Cancer stem cells (CSCs) are potential targets for innovative anticancer therapies that involve natural products with potential chemopreventive effects. We…”
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Selective anticancer effects of a synthetic flavagline on human Oct4-expressing cancer stem-like cells via a p38 MAPK-dependent caspase-3-dependent pathway
Published in Biochemical pharmacology (15-05-2014)“…Cancer stem cells (CSCs) are considered as the initiators of the carcinogenic process and are therefore emerging targets for innovative anticancer therapies…”
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Pro-differentiating effects of a synthetic flavagline on human teratocarcinomal cancer stem-like cells
Published in Cell biology and toxicology (01-06-2017)“…As initiators of the carcinogenic process, cancer stem cells (CSCs) are considered as new targets for anti-cancer therapies. However, these cells are hidden in…”
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Phenotype-specific apoptosis induced by three new triterpenoid saponins from Albizia glaberrima (Schumach. & Thonn.) Benth
Published in Fitoterapia (01-03-2016)“…As part of our search of new bioactive saponins from Cameroonian medicinal plants, phytochemical investigation of the roots of Albizia glaberrima led to the…”
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The synthetic flavagline FL3 spares normal human skin cells from its cytotoxic effect via an activation of Bad
Published in Toxicology in vitro (01-10-2019)“…The molecular pathways by which flavagline derivatives exert their cytotoxicity against various cancer cell types are well documented, while the mechanisms…”
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HIV-1 Vpr mediates the depletion of the cellular repressor CTIP2 to counteract viral gene silencing
Published in Scientific reports (11-09-2019)“…Mammals have evolved many antiviral factors impacting different steps of the viral life cycle. Associated with chromatin-modifying enzymes, the cellular…”
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Anti-inflammatory, analgesic activities and gastro-protective effects of the phenolic contents of the red alga, Laurencia obtusa
Published in European journal of integrative medicine (01-06-2016)“…The present study was conducted to evaluate anti-inflammatory, analgesic and gastro-protective activities of methanol/dichloromethane extract and its…”
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Pro-apoptotic activity of acylated triterpenoid saponins from the stem bark of Albizia chevalieri harms
Published in Phytochemistry letters (01-12-2017)“…As a continuation of our interest in apoptosis-inducing triterpenoid saponins from Albizia genus, phytochemical investigation of the stem bark of Albizia…”
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