Search Results - "Ali, Sahar A."

Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors by Ali, Sahar A., Awad, Samir Mohamed, Said, Ahmed Mohammed, Mahgoub, Shahenda, Taha, Heba, Ahmed, Naglaa Mohamed

“…Oxidative stress is one of the main causes of significant severe diseases. The discovery of new potent antioxidants with high efficiency and low toxicity is a…”
Get full text

Characterization of Candida species isolated from clinical specimens: insights into virulence traits, antifungal resistance and molecular profiles by Makled, Amal F, Ali, Sahar A M, Labeeb, Azza Z, Salman, Samar S, Shebl, Doaa Z M, Hegazy, Sarah G, Sabal, Mona S

“…Candida species have emerged as a significant cause of opportunistic infections. Alongside the expression of various virulence factors, the rise of antifungal…”
Get full text

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition by Abd El-Hameed, Rania H., Mahgoub, Shahenda, El-Shanbaky, Hend M., Mohamed, Mosaad S., Ali, Sahar A.

“…Inflammation is associated with the development of several diseases comprising cancer and cardiovascular disease. Agents that suppress cyclooxygenase (COX) and…”
Get full text

Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents by Awad, Samir M, Zohny, Yasser M, Ali, Sahar A, Mahgoub, Shahenda, Said, Ahmed M

“…Hyperthyroidism is the result of uncontrolled overproduction of the thyroid hormones. One of the mostly used antithyroid agents is 6- propyl-2-thiouracil…”
Get full text

Inflammasome Genes’ Polymorphisms in Egyptian Chronic Hepatitis C Patients: Influence on Vulnerability to Infection and Response to Treatment by Soror, Sameh H. A., Mohamed Seif, Sameh, Ali, S. A., Estfanous, Shady Z. K., Abdelaziz, Dalia H. A.

“…Chronic inflammation is a pivotal contributor to the liver damage mediated by hepatitis C virus (HCV). The NOD-like receptor, pyrin domain-containing 3 (NLRP3)…”
Get full text

Screening of latent tuberculosis infection among health care workers working in Hajj pilgrimage area in Saudi Arabia, using interferon gamma release assay and tuberculin skin test by Bukhary, Zakeya A, Amer, Soliman M, Emara, Magdy M, Abdalla, Mohammad E, Ali, Sahar A

“…Interferon gamma release assays (IGRA) is highly specific for Mycobacterium tuberculosis and is the preferred test in BCG-vaccinated individuals. The few…”
Get full text

Urinary Urea, Uric Acid and Hippuric Acid as Potential Biomarkers in Multiple Sclerosis Patients by Atya, Hanaa B., Ali, Sahar A., Hegazy, Mohamed I., El Sharkawi, Fathia Z.

“…Urine is a proven source of metabolite biomarkers and has the potential to be a rapid, noninvasive, inexpensive, and efficient diagnostic tool for various…”
Get full text

Angiotensin-Converting Enzyme-2 (ACE-2) with Interferon-Induced Transmembrane Protein-3 (IFITM-3) Genetic Variants and Interleukin-6 as Severity and Risk Predictors among COVID-19 Egyptian Population by Makled, Amal F., Ali, Sahar A. M., Eldahdouh, S. S., Sleem, Asmaa S., Eldahshan, Maha M., Elsaadawy, Yara, Salman, Samar S., Mohammed Elbrolosy, Asmaa

“…Introduction. The host genetic background is a crucial factor that underlies the interindividual variability of COVID-19 fatality and outcomes…”
Get full text

Camptothecin Sensitizes Hepatocellular Carcinoma Cells to Sorafenib- Induced Ferroptosis Via Suppression of Nrf2 by Elkateb, Ahmed S., Nofal, Shahira, Ali, Sahar A., Atya, Hanaa B.

“…Sorafenib is a potent inducer of ferroptosis used to manage hepatocellular carcinoma (HCC). The ferroptosis induced by sorafenib activates the p62–Keap1–Nrf2…”
Get full text

The protective effect of Phoenix dactylifera L. seeds against CCl4-induced hepatotoxicity in rats by Abdelaziz, Dalia H.A., Ali, Sahar A.

“…In traditional Egyptian medicine, Phoenix dactylifera L. (date palm) seeds are listed in folk remedies for the management of diabetes, liver diseases and…”
Get full text

CTX Correlation to Disease Duration and Adiponectin in Egyptian Children with T1DM by Hashim, Amel A, Ali, Sahar A, Emara, Ibrahim A, El-Hefnawy, Mohamed H

“…In this study, we investigated the relationship of adiponectin with bone marker changes in Egyptian children and adolescents with T1DM and the effect of…”
Get full text

Melaleuca rugulosa (Link) Craven Tannins: Appraisal of anti-inflammatory, radical scavenging activities, and molecular modeling studies by Ebrahim, Hassan Y., Mady, Mohamed S., Atya, Hanaa B., Ali, Sahar A., Elsayed, Heba E., Moharram, Fatma A.

“…Genus Melaleuca or tea tree species are well known to be an important source of biological active oils and extracts. The biological significance appears in…”
Get full text

Role of different direct-acting antiviral drugs on hepatitis C virus-associated mixed cryoglobulinemia in Egyptian patients by Elshazly, Tarek A., Elrabat, Amr M., Ali, Sahar A. M., Diasty, Muhammed, El-Desoky, Mohamed

“…Background Several extrahepatic manifestations have been reported and mixed cryoglobulinemia is a clonal disorder of B cells which is strongly associated with…”
Get full text

The combined effect of IL-17F and CCL20 gene polymorphism in susceptibility to multiple sclerosis in Egypt by El Sharkawi, Fathia Z., Ali, Sahar A., Hegazy, Mohamed I., Atya, Hanaa B.

“…Levels of CCL20 and its CCR6 receptor are elevated in many autoimmune diseases which help in the recruitment of T helper (Th17) cells to site of inflammation…”
Get full text

Chitinase 3‐like‐1, Tolloid‐like protein 1, and intergenic gene polymorphisms are predictors for hepatocellular carcinoma development after hepatitis C virus eradication by direct‐acting antivirals by Mangoud, Nadia O. M., Ali, Sahar A., El Kassas, Mohamed, Soror, Sameh H.

“…Hepatocellular carcinoma (HCC) is a major cause of cancer death in Egypt. There is still a risk for HCC development even after eradicating hepatitis C virus…”
Get full text

Effects of gamma-irradiation on antibiotic resistance and diagnostic molecular markers of methicillin-resistant Staphylococcus aureus in Egyptian cancer patients by Shehata, Mona M. K., Radwan, Samah Mohamed, Ali, Sahar A. M.

“…Purpose: This in-vitro study aimed to assess in 120 [40 community-acquired (CA-MRSA) & 80 hospital-acquired (HA-MRSA)] isolates from cancer patients whether…”
Get full text

New phenolic compounds from Calothamnus quadrifidus R.Br. aerial parts and their antioxidant activity by Ibrahim, Reham R., Ibrahim, Haitham A., Shabana, Samah S., El-Hosari, Doaa G, Ali, Sahar A., Mahgoub, Shahenda, Moharram, Fatma A.

“…Two new compounds calothphenone (1) and 6-methoxy kaempferol 3-O-(6″-E-p-coumaroyl)-β- d-glucopyranoside (6-methoxy tiliroside) (2) along with six known…”
Get full text

A pilot study of Livin gene and Yes-associated protein 1 expression in hepatocellular carcinoma patients by Badr, Eman AE, El Tantawy El Sayed, Ibrahim, Assar, Mohamed FA, Ali, Sahar AM, Ibrahim, Nehal S.

“…Livin gene and Yes-Associated Protein 1 (YAP1 (play a pivotal role in organ size control and tumorigenesis. In the present pilot study, we investigate the…”
Get full text

Phoenix dactylifera seeds ameliorate early diabetic complications in streptozotocin-induced diabetic rats by Abdelaziz, Dalia H A, Ali, Sahar A, Mostafa, Mahmoud M A

“…In Arabic folk medicine, the seeds of Phoenix dactylifera L. (Arecaceae) have been used to manage diabetes for many years. Few studies have reported the…”
Get more information

Alterations in serum levels of fetuin A and selenoprotein P in chronic hepatitis C patients with concomitant type 2 diabetes: A case-control study by Ali, Sahar A, Nassif, Walaa M.H, Abdelaziz, Dalia H.A

“…Summary Background Insulin resistance (IR) and type 2 diabetes mellitus (T2DM) are serious extrahepatic manifestations of chronic hepatitis C virus (HCV)…”
Get full text