IgG and IgA levels determination in semen liquid: interest for the biological investigation of infertility

We studied the relationship between spermogram parameters and biochemical elements in seminal plasma. In this way we searched an association between immunoglobulin levels in seminal plasma and spermogram parameters. The spermogram is usually performed in our laboratory for investigation of infertili...

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Bibliographic Details
Published in:	Annales de biologie clinique (Paris) Vol. 67; no. 6; p. 613
Main Authors:	Limam, M, Zorgati, Mm, Zarrouk, A, Ali, S Ben Hadj, Bouras, S, Ammar, S Ben
Format:	Journal Article
Language:	French
Published:	France 01-11-2009
Subjects:	Diagnosis, Differential Ejaculation - physiology Humans Immunoelectrophoresis Immunoglobulin A - analysis Immunoglobulin G - analysis Infertility, Male - diagnosis Infertility, Male - immunology Male Reference Values Semen - immunology Sperm Count Sperm Motility Sperm Tail - physiology
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Summary:	We studied the relationship between spermogram parameters and biochemical elements in seminal plasma. In this way we searched an association between immunoglobulin levels in seminal plasma and spermogram parameters. The spermogram is usually performed in our laboratory for investigation of infertility. Using immunonephelometry, we measured immunoglobulin (Ig) G and A levels in the seminal plasma of 17 patients. Averages levels of IgG and IgA were 83.3 and 33.6 mg/L, respectively. IgG and IgA levels appeared to be significantly different (p = 0.001), and were significantly associated. A correlation between IgG values and coiled tails percentage was noted in patients having IgA below 20 mg/L (p < 0,001). In conclusion, the measurement of IgG and IgA levels in seminal plasma might constitute a valuable diagnosis tool for the evaluation of infertility.
ISSN:	0003-3898
DOI:	10.1684/abc.2009.0379