Search Results - "Ali, Md Khadem"

Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma by Ali, Md Khadem, Kim, Richard Y, Brown, Alexandra C, Mayall, Jemma R, Karim, Rafia, Pinkerton, James W, Liu, Gang, Martin, Kristy L, Starkey, Malcolm R, Pillar, Amber L, Donovan, Chantal, Pathinayake, Prabuddha S, Carroll, Olivia R, Trinder, Debbie, Tay, Hock L, Badi, Yusef E, Kermani, Nazanin Z, Guo, Yi-Ke, Aryal, Ritambhara, Mumby, Sharon, Pavlidis, Stelios, Adcock, Ian M, Weaver, Jessica, Xenaki, Dikaia, Oliver, Brian G, Holliday, Elizabeth G, Foster, Paul S, Wark, Peter A, Johnstone, Daniel M, Milward, Elizabeth A, Hansbro, Philip M, Horvat, Jay C

“…Accumulating evidence highlights links between iron regulation and respiratory disease. Here, we assessed the relationship between iron levels and regulatory…”
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Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa by Vidaillac, Celine, Yong, Valerie Fei Lee, Aschtgen, Marie-Stephanie, Qu, Jing, Yang, Shuowei, Xu, Guangfu, Seng, Zi Jing, Brown, Alexandra C., Ali, Md Khadem, Jaggi, Tavleen K., Sankaran, Jagadish, Foo, Yong Hwee, Righetti, Francesco, Nedumaran, Anu Maashaa, Mac Aogáin, Micheál, Roizman, Dan, Richard, Jean-Alexandre, Rogers, Thomas R., Toyofuku, Masanori, Luo, Dahai, Loh, Edmund, Wohland, Thorsten, Czarny, Bertrand, Horvat, Jay C., Hansbro, Philip M., Yang, Liang, Li, Liang, Normark, Staffan, Henriques-Normark, Birgitta, Chotirmall, Sanjay H.

“…Molecular mechanisms by which sex steroids interact with P. aeruginosa to modulate its virulence have yet to be reported. Our work provides the first…”
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Knockdown of the host cellular protein transportin 3 attenuates prototype foamy virus infection by Ali, Md. Khadem, Kim, Jinsun, Hamid, Faysal Bin, Shin, Cha-Gyun

“…Transportin 3 (TNPO3) is a member of the importin-ß superfamily proteins. Despite numerous studies, the exact molecular mechanism of TNPO3 in retroviral…”
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The Role of Zinc in the Pathogenesis of Lung Disease by Liu, Xiaoying, Ali, Md Khadem, Dua, Kamal, Xu, Ran

“…Lung diseases, such as asthma, chronic obstructive pulmonary diseases (COPD), and cystic fibrosis (CF), are among the leading causes of mortality and morbidity…”
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Nuclear Localization Signals in Prototype Foamy Viral Integrase for Successive Infection and Replication in Dividing Cells by Hossain, Md. Alamgir, Ali, Md. Khadem, Shin, Cha-Gyun

“…We identified four basic amino acid residues as nuclear localization signals (NLS) in the C-terminal domain of the prototype foamy viral (PFV) integrase (IN)…”
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Structural and functional insights into foamy viral integrase by Hossain, Md Alamgir, Ali, Md Khadem, Shin, Cha-Gyun

“…Successful integration of retroviral DNA into the host chromosome is an essential step for viral replication. The process is mediated by virally encoded…”
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Critical role for iron accumulation in the pathogenesis of fibrotic lung disease by Ali, Md Khadem, Kim, Richard Y, Brown, Alexandra C, Donovan, Chantal, Vanka, Kanth S, Mayall, Jemma R, Liu, Gang, Pillar, Amber L, Jones‐Freeman, Bernadette, Xenaki, Dikaia, Borghuis, Theo, Karim, Rafia, Pinkerton, James W, Aryal, Ritambhara, Heidari, Moones, Martin, Kristy L, Burgess, Janette K, Oliver, Brian G, Trinder, Debbie, Johnstone, Daniel M, Milward, Elizabeth A, Hansbro, Philip M, Horvat, Jay C

“…Increased iron levels and dysregulated iron homeostasis, or both, occur in several lung diseases. Here, the effects of iron accumulation on the pathogenesis of…”
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The emerging diagnostic and therapeutic roles of small nucleolar RNAs in lung diseases by Liu, Xiaoying, Ali, Md Khadem, Zhao, Lan, Dua, Kamal, Mao, Yuqiang

“…Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules that range from 60 to 300 nucleotides in length and are primarily located in the nucleoli of cells…”
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Arteriovenous Malformations—Current Understanding of the Pathogenesis with Implications for Treatment by Schimmel, Katharina, Ali, Md Khadem, Tan, Serena Y., Teng, Joyce, Do, Huy M., Steinberg, Gary K., Stevenson, David A., Spiekerkoetter, Edda

“…Arteriovenous malformations are a vascular anomaly typically present at birth, characterized by an abnormal connection between an artery and a vein (bypassing…”
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Emerging role of long non-coding RNA MALAT1 related signaling pathways in the pathogenesis of lung disease by Liu, Jun, Ali, Md Khadem, Mao, Yuqiang

“…Long non-coding RNAs (lncRNAs) are endogenously expressed RNAs longer than 200 nt that are not translated into proteins. In general, lncRNAs bind to mRNA,…”
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Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma by Pinkerton, James W., Kim, Richard Y., Brown, Alexandra C., Rae, Brittany E., Donovan, Chantal, Mayall, Jemma R., Carroll, Olivia R., Khadem Ali, Md, Scott, Hayley A., Berthon, Bronwyn S., Baines, Katherine J., Starkey, Malcolm R., Kermani, Nazanin Z., Guo, Yi-Ke, Robertson, Avril A.B., O’Neill, Luke A.J., Adcock, Ian M., Cooper, Matthew A., Gibson, Peter G., Wood, Lisa G., Hansbro, Philip M., Horvat, Jay C.

“…Obesity is a risk factor for asthma, and obese asthmatic individuals are more likely to have severe, steroid-insensitive disease. How obesity affects the…”
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Comparative sequence and expression analyses of African green monkey (Cercopithecus aethiops) TNPO3 from CV-1 cells by Khadem Ali, Md, Alamgir Hossain, Md, Shin, Cha-Guyn

“…Transportin 3 (TNPO3 or TRN-SR2) is a key host cellular factor involved in the early steps of several lentiviral replications. In the present study, we cloned…”
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Role of Long Non-Coding RNAs in Pulmonary Arterial Hypertension by Han, Yun, Ali, Md Khadem, Dua, Kamal, Spiekerkoetter, Edda, Mao, Yuqiang

“…Pulmonary arterial hypertension (PAH) is a debilitating condition of the pulmonary circulatory system that occurs in patients of all ages and if untreated,…”
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Aim2 suppresses cigarette smoke‐induced neutrophil recruitment, neutrophil caspase‐1 activation and anti‐Ly6G‐mediated neutrophil depletion by Donovan, Chantal, Kim, Richard Y, Galvao, Izabela, Jarnicki, Andrew G, Brown, Alexandra C, Jones‐Freeman, Bernadette, Gomez, Henry M, Wadhwa, Ridhima, Hortle, Elinor, Jayaraman, Ranjith, Khan, Haroon, Pickles, Sophie, Sahu, Priyanka, Chimankar, Vrushali, Tu, Xiaofan, Ali, Md Khadem, Mayall, Jemma R, Nguyen, Duc H, Budden, Kurtis F, Kumar, Vinod, Schroder, Kate, Robertson, Avril AB, Cooper, Matthew A, Wark, Peter AB, Oliver, Brian G, Horvat, Jay C, Hansbro, Philip M

“…Increased inflammasome responses are strongly implicated in inflammatory diseases; however, their specific roles are incompletely understood. Therefore, we…”
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Circular RNAs: emerging players in asthma and COPD by Liu, Xiaoying, Ali, Md Khadem, Dua, Kamal, Mao, Yuqiang, Liu, Jun

“…Circular RNAs (circRNAs) belong to a unique class of endogenously expressed non-protein-coding RNAs with a distinct circularized structure, characterized by…”
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Investigating the Links between Lower Iron Status in Pregnancy and Respiratory Disease in Offspring Using Murine Models by Gomez, Henry M, Pillar, Amber L, Brown, Alexandra C, Kim, Richard Y, Ali, Md Khadem, Essilfie, Ama-Tawiah, Vanders, Rebecca L, Frazer, David M, Anderson, Gregory J, Hansbro, Philip M, Collison, Adam M, Jensen, Megan E, Murphy, Vanessa E, Johnstone, Daniel M, Reid, David, Milward, Elizabeth A, Donovan, Chantal, Horvat, Jay C

“…Maternal iron deficiency occurs in 40-50% of all pregnancies and is associated with an increased risk of respiratory disease and asthma in children. We used…”
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PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension by Ali, Md Khadem, Tian, Xuefei, Zhao, Lan, Schimmel, Katharina, Rhodes, Christopher J, Wilkins, Martin R, Nicolls, Mark R, Spiekerkoetter, Edda F

“…Bone morphogenic protein receptor 2 (BMPR2) expression and signaling are impaired in pulmonary arterial hypertension (PAH). How BMPR2 signaling is decreased in…”
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Erratum for Vidaillac et al. “Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa” by Vidaillac, Celine, Yong, Valerie Fei Lee, Aschtgen, Marie-Stephanie, Qu, Jing, Yang, Shuowei, Xu, Guangfu, Seng, Zi Jing, Brown, Alexandra C., Ali, Md Khadem, Jaggi, Tavleen K., Sankaran, Jagadish, Foo, Yong Hwee, Righetti, Francesco, Nedumaran, Anu Maashaa, Mac Aogáin, Micheál, Roizman, Dan, Richard, Jean-Alexandre, Rogers, Thomas R., Toyofuku, Masanori, Luo, Dahai, Loh, Edmund, Wohland, Thorsten, Czarny, Bertrand, Horvat, Jay C., Hansbro, Philip M., Yang, Liang, Li, Liang, Normark, Staffan, Henriques-Normark, Birgitta, Chotirmall, Sanjay H.

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Nuclear localization signals in prototype foamy viral integrase for successive infection and replication in dividing cells by Hossain, Alamgir, Ali, Khadem, Shin, Cha-Gyun

“…We identified four basic amino acid residues as nuclear localization signals (NLS) in the C-terminal domain of the prototype foamy viral (PFV) integrase (IN)…”
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IL-22 Binding Protein/IL-22 Axis in Regulating Acute Lung Injury by Pillar, Amber, Ali, Md Khadem

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