Search Results - "Ali, M.Showkat"

Tyrosine Kinase Activation by the Angiotensin II Receptor in the Absence of Calcium Signaling by Doan, T.N., Ali, M.Showkat, Bernstein, K.E.

“…The angiotensin II type 1 (AT1) receptor signals via heterotrimeric G-proteins and intracellular tyrosine kinases. Here, we investigate a modified AT1…”
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The critical role of c-Src and the Shc/Grb2/ERK2 signaling pathway in angiotensin II-dependent VSMC proliferation by Sayeski, Peter P., Ali, M.Showkat

“…Angiotensin II promotes vascular smooth muscle cell proliferation through the actions of the G protein-coupled AT 1 receptor. Recent evidence suggest that the…”
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Selective down-regulation of angiotensin II receptor type 1A signaling by protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells by Doan, Thanh, Farmer, Paul, Cooney, Thomas, Ali, M.Showkat

“…The heptahelical AT 1 G-protein-coupled receptor lacks inherent tyrosine kinase activity. Angiotensin II binding to AT 1 nevertheless activates several…”
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Jak2 Acts as Both a STAT1 Kinase and as a Molecular Bridge Linking STAT1 to the Angiotensin II AT1 Receptor by Ali, M.Showkat, Sayeski, Peter P., Bernstein, Kenneth E.

“…Angiotensin II activates the Jak-STAT pathway via the AT1 receptor. We studied two mutant AT1 receptors, termed M5 and M6, that contain Y to F substitutions…”
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Angiotensin II signal transduction pathways by Sayeski, Peter P., Ali, M.Showkat, Semeniuk, Dan J., Doan, Thanh N., Bernstein, Kenneth E.

“…It has been 100 years since the discovery of renin by Tigerstedt and Bergman. Since that time, numerous discoveries have advanced our understanding of the…”
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Janus Kinase 2 (Jak2) Must Be Catalytically Active to Associate with the AT1Receptor in Response to Angiotensin II by Ali, M.Showkat, Sayeski, P.P., Safavi, A., Lyles, M., Bernstein, K.E.

“…Angiotensin II evokes a variety of biological responses by binding to a seven transmembrane cell surface receptor termed AT1. Ligand binding to the AT1receptor…”
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Identification of the Tryptophan Residue in the Thiamin Pyrophosphate Binding Site of Mammalian Pyruvate Dehydrogenase (∗) by Ali, M.Showkat, Shenoy, Bhami C., Eswaran, Devayani, Andersson, Laura A., Roche, Thomas E., Patel, Mulchand S.

“…The pyruvate dehydrogenase (E1) component of the mammalian pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate with the…”
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