Search Results - "Ali, Lizna"

Cross- and Co-Packaging of Retroviral RNAs and Their Consequences by Ali, Lizna M, Rizvi, Tahir A, Mustafa, Farah

“…Retroviruses belong to the family and are ribonucleoprotein (RNP) particles that contain a dimeric RNA genome. Retroviral particle assembly is a complex…”
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Identification of a putative Gag binding site critical for feline immunodeficiency virus genomic RNA packaging by Krishnan, Anjana, Ali, Lizna M, Prabhu, Suresha G, Pillai, Vineeta N, Chameettachal, Akhil, Vivet-Boudou, Valérie, Bernacchi, Serena, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A

“…The retroviral Gag precursor plays a central role in the selection and packaging of viral genomic RNA (gRNA) by binding to virus-specific packaging signal(s)…”
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Packaging of Mason-Pfizer monkey virus (MPMV) genomic RNA depends upon conserved long-range interactions (LRIs) between U5 and gag sequences by Kalloush, Rawan M, Vivet-Boudou, Valérie, Ali, Lizna M, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A

“…MPMV has great potential for development as a vector for gene therapy. In this respect, precisely defining the sequences and structural motifs that are…”
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A purine loop and the primer binding site are critical for the selective encapsidation of mouse mammary tumor virus genomic RNA by Pr77Gag by Chameettachal, Akhil, Vivet-Boudou, Valérie, Pitchai, Fathima Nuzra Nagoor, Pillai, Vineeta N, Ali, Lizna Mohamed, Krishnan, Anjana, Bernacchi, Serena, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A

“…Abstract Retroviral RNA genome (gRNA) harbors cis-acting sequences that facilitate its specific packaging from a pool of other viral and cellular RNAs by…”
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The bifurcated stem loop 4 (SL4) is crucial for efficient packaging of mouse mammary tumor virus (MMTV) genomic RNA by Mustafa, Farah, Vivet-Boudou, Valérie, Jabeen, Ayesha, Ali, Lizna M., Kalloush, Rawan M., Marquet, Roland, Rizvi, Tahir A.

“…Packaging the mouse mammary tumor virus (MMTV) genomic RNA (gRNA) requires the entire 5ʹ untranslated region (UTR) in conjunction with the first 120…”
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A cis-Acting Element Downstream of the Mouse Mammary Tumor Virus Major Splice Donor Critical for RNA Elongation and Stability by Akhlaq, Shaima, Panicker, Neena G., Philip, Pretty S., Ali, Lizna M., Dudley, Jaquelin P., Rizvi, Tahir A., Mustafa, Farah

“…The mouse mammary tumor virus (MMTV) encodes a functional signal peptide, a cleavage product of envelope and Rem proteins. Signal peptide interacts with a 3′…”
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Identification of Pr78Gag Binding Sites on the Mason-Pfizer Monkey Virus Genomic RNA Packaging Determinants by Pitchai, Fathima Nuzra Nagoor, Chameettachal, Akhil, Vivet-Boudou, Valérie, Ali, Lizna Mohamed, Pillai, Vineeta N., Krishnan, Anjana, Bernacchi, Serena, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A.

“…[Display omitted] •MPMV Pr78Gag captures Psi RNA structure from a mix of cellular/spliced viral RNAs.•Pr78Gag binds to ssPurines and A252AGUGUU258 loop within…”
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Expression, purification, and characterization of biologically active full-length Mason-Pfizer monkey virus (MPMV) Pr78Gag by Pitchai, Fathima Nuzra Nagoor, Ali, Lizna, Pillai, Vineeta Narayana, Chameettachal, Akhil, Ashraf, Syed Salman, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir Aziz

“…MPMV precursor polypeptide Pr78 Gag orchestrates assembly and packaging of genomic RNA (gRNA) into virus particles. Therefore, we have expressed recombinant…”
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Stabilizing role of structural elements within the 5´ Untranslated Region (UTR) and gag sequences in Mason-Pfizer monkey virus (MPMV) genomic RNA packaging by Kalloush, Rawan M., Vivet-Boudou, Valérie, Ali, Lizna M., Pillai, Vineeta N., Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A.

“…The Mason-Pfizer monkey virus (MPMV) genomic RNA (gRNA) packaging signal is a highly-structured element with several stem-loops held together by two…”
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Virus detection and quantification using electrical parameters by Ahmad, Mahmoud Al, Mustafa, Farah, Ali, Lizna M., Rizvi, Tahir A.

“…Here we identify and quantitate two similar viruses, human and feline immunodeficiency viruses (HIV and FIV), suspended in a liquid medium without labeling,…”
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Structural basis of genomic RNA (gRNA) dimerization and packaging determinants of mouse mammary tumor virus (MMTV) by Aktar, Suriya J, Vivet-Boudou, Valérie, Ali, Lizna M, Jabeen, Ayesha, Kalloush, Rawan M, Richer, Delphine, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A

“…One of the hallmarks of retroviral life cycle is the efficient and specific packaging of two copies of retroviral gRNA in the form of a non-covalent RNA dimer…”
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Label-Free Capacitance-Based Identification of Viruses by Ahmad, Mahmoud Al, Mustafa, Farah, Ali, Lizna M., Karakkat, Jimsheena V., Rizvi, Tahir A.

“…This study was undertaken to quantitate a single virus suspension in culture medium without any pre-processing. The electrical capacitance per virus particle…”
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Biochemical and Functional Characterization of Mouse Mammary Tumor Virus Full-Length Pr77$^{Gag}$ Expressed in Prokaryotic and Eukaryotic Cells by Chameettachal, Akhil, Pillai, Vineeta, Ali, Lizna, Pitchai, Fathima, Ardah, Mustafa, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir

“…The mouse mammary tumor virus (MMTV) Pr77$^{Gag}$ polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be…”
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Biochemical and Functional Characterization of Mouse Mammary Tumor Virus Full-Length Pr77Gag Expressed in Prokaryotic and Eukaryotic Cells by Chameettachal, Akhil, Pillai, Vineeta, Ali, Lizna, Pitchai, Fathima, Ardah, Mustafa, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir

“…The mouse mammary tumor virus (MMTV) Pr77Gag polypeptide is an essential retroviral structural protein without which infectious viral particles cannot be…”
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SHAPE analysis of the 5' end of the Mason-Pfizer monkey virus (MPMV) genomic RNA reveals structural elements required for genome dimerization by Aktar, Suriya J, Jabeen, Ayesha, Ali, Lizna M, Vivet-Boudou, Valérie, Marquet, Roland, Rizvi, Tahir A

“…Earlier genetic and structural prediction analyses revealed that the packaging determinants of Mason Pfizer monkey virus (MPMV) include two discontinuous core…”
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Role of Purine-Rich Regions in Mason-Pfizer Monkey Virus (MPMV) Genomic RNA Packaging and Propagation by Ali, Lizna Mohamed, Pitchai, Fathima Nuzra Nagoor, Vivet-Boudou, Valérie, Chameettachal, Akhil, Jabeen, Ayesha, Pillai, Vineeta N., Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A.

“…A distinguishing feature of the Mason-Pfizer monkey virus (MPMV) packaging signal RNA secondary structure is a single-stranded purine-rich sequence (ssPurines)…”
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Expression, purification, and functional characterization of soluble recombinant full-length simian immunodeficiency virus (SIV) Pr55Gag by Pillai, Vineeta N., Ali, Lizna Mohamed, Prabhu, Suresha G., Krishnan, Anjana, Tariq, Saeed, Mustafa, Farah, Rizvi, Tahir A.

“…The simian immunodeficiency virus (SIV) precursor polypeptide Pr55Gag drives viral assembly and facilitates specific recognition and packaging of the SIV…”
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Purification and Functional Characterization of a Biologically Active Full-Length Feline Immunodeficiency Virus (FIV) Pr50Gag by Krishnan, Anjana, Pillai, Vineeta N., Chameettachal, Akhil, Mohamed Ali, Lizna, Nuzra Nagoor Pitchai, Fathima, Tariq, Saeed, Mustafa, Farah, Marquet, Roland, A. Rizvi, Tahir

“…The feline immunodeficiency virus (FIV) full-length Pr50Gag precursor is a key player in the assembly of new viral particles. It is also a critical component…”
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MMTV RNA packaging requires an extended long-range interaction for productive Gag binding to packaging signals by Prabhu, Suresha G, Pillai, Vineeta N, Ali, Lizna Mohamed, Vivet-Boudou, Valérie, Chameettachal, Akhil, Bernacchi, Serena, Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A

“…The packaging of genomic RNA (gRNA) into retroviral particles relies on the specific recognition by the Gag precursor of packaging signals (Psi), which…”
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A Stretch of Unpaired Purines in the Leader Region of Simian Immunodeficiency Virus (SIV) Genomic RNA is Critical for its Packaging into Virions by Pillai, Vineeta N., Ali, Lizna Mohamed, Prabhu, Suresha G., Krishnan, Anjana, Chameettachal, Akhil, Pitchai, Fathima Nuzra Nagoor, Mustafa, Farah, Rizvi, Tahir A.

“…[Display omitted] •Single stranded purines (ssPurines) are crucial for retroviral gRNA packaging.•ssPurines I-IV are identified in the SHAPE-validated…”
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