Search Results - "Ali, Lamiaa M. A"
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Two-Photon Absorbing AIEgens: Influence of Stereoconfiguration on Their Crystallinity and Spectroscopic Properties and Applications in Bioimaging
Published in ACS applied materials & interfaces (09-12-2020)“…This paper aims at designing chromophores with efficient aggregation-induced emission (AIE) properties for two-photon fluorescence microscopy (2PFM), which is…”
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Encapsulation of Upconversion Nanoparticles in Periodic Mesoporous Organosilicas
Published in Molecules (Basel, Switzerland) (09-11-2019)“…(1) Background: Nanomedicine has recently emerged as a promising field, particularly for cancer theranostics. In this context, nanoparticles designed for…”
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Topological Requirements for CI-M6PR-Mediated Cell Uptake
Published in Bioconjugate chemistry (16-10-2019)“…The 300 kDa cation-independent M6P receptor (CI-MPR) mediates ligand internalization and trafficking to the endolysosomal compartments. Because of its…”
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Photosensitivity of Different Nanodiamond-PMO Nanoparticles in Two-Photon-Excited Photodynamic Therapy
Published in Life (Basel, Switzerland) (01-12-2022)“…In addition to their great optical properties, nanodiamonds (NDs) have recently proved useful for two-photon-excited photodynamic therapy (TPE-PDT)…”
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The Anti-Obesity Potential of Superparamagnetic Iron Oxide Nanoparticles against High-Fat Diet-Induced Obesity in Rats: Possible Involvement of Mitochondrial Biogenesis in the Adipose Tissues
Published in Pharmaceutics (01-10-2022)“…Background: Obesity is a pandemic disease that is rapidly growing into a serious health problem and has economic impact on healthcare systems. This bleak image…”
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Biological Assessment of Laser-Synthesized Silicon Nanoparticles Effect in Two-Photon Photodynamic Therapy on Breast Cancer MCF-7 Cells
Published in Nanomaterials (Basel, Switzerland) (26-07-2020)“…Driven by their distinctive physiological activities, biological properties and unique theranostic modalities, silicon nanoparticles (SiNPs) are one of the…”
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Upscale Synthesis of Magnetic Mesoporous Silica Nanoparticles and Application to Metal Ion Separation: Nanosafety Evaluation
Published in Nanomaterials (Basel, Switzerland) (16-12-2023)“…The synthesis of core-shell magnetic mesoporous nanoparticles (MMSNs) through a phase transfer process is usually performed at the 100-250 mg scale. At the…”
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Super-resolution imaging of antibody-conjugated biodegradable periodic mesoporous organosilica nanoparticles for targeted chemotherapy of prostate cancer
Published in Nanoscale (20-07-2023)“…Biodegradable periodic mesoporous organosilica nanoparticles (nanoPMOs) are widely used as responsive drug delivery platforms for targeted chemotherapy of…”
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Periodic Mesoporous Ionosilica Nanoparticles for Green Light Photodynamic Therapy and Photochemical Internalization of siRNA
Published in ACS applied materials & interfaces (30-06-2021)“…We report periodic mesoporous ionosilica nanoparticles (PMINPs) as versatile nano-objects for imaging, photodynamic therapy (PDT), and efficient adsorption and…”
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Hemostasis disorders caused by polymer coated iron oxide nanoparticles
Published in Journal of biomedical nanotechnology (01-07-2013)“…Superparamagnetic iron oxide nanoparticles (SPIONs) are inorganic nanomaterials gaining strong clinical interest due to their increasing number of biological…”
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Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins
Published in Frontiers in immunology (2024)“…Inducing the degradation of pathological soluble antigens could be the key to greatly enhancing the efficacy of therapeutic monoclonal antibodies (mAbs),…”
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Modified Indulines: From Dyestuffs to In Vivo Theranostic Agents
Published in ACS applied materials & interfaces (07-07-2021)“…The efficient, versatile, and straightforward synthesis of the first N-alkyl analogues of induline 3B (8a and 8b) is reported. Thanks to the introduction of…”
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Superparamagnetic Spinel-Ferrite Nano-Adsorbents Adapted for Hg2+, Dy3+, Tb3+ Removal/Recycling: Synthesis, Characterization, and Assessment of Toxicity
Published in International journal of molecular sciences (13-06-2023)“…In the present work, superparamagnetic adsorbents based on 3-aminopropyltrimethoxy silane (APTMS)-coated maghemite (γFe2O3@SiO2–NH2) and cobalt ferrite…”
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14
Wound Dressings Based on Sodium Alginate-Polyvinyl Alcohol- Moringa oleifera Extracts
Published in Pharmaceutics (18-04-2023)“…Biopolymers have significant pharmaceutical applications, and their blending has favorable characteristics for their pharmaceutical properties compared to the…”
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Imidazopyridine-fused [1,3]diazepinones: modulations of positions 2 to 4 and their impacts on the anti-melanoma activity
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2020)“…A series of 19 novel pyrido-imidazodiazepinones, with modulations of positions 2, 3 and 4 of the diazepine ring were synthesised and screened for their…”
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Thiochromenocarbazole imide-based photosensitizers decorated with carbonic anhydrase inhibitors for the targeted treatment of hypoxic tumours
Published in Materials advances (20-05-2024)“…PDT has gained growing interest as a prospective approach for cancer therapy, thanks to its minimal invasiveness and low systemic toxicity, making it a…”
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Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery
Published in Nanomaterials (Basel, Switzerland) (25-11-2020)“…Small interfering RNAs (siRNAs) are promising molecules for developing new therapies based on gene silencing; however, their delivery into cells remains an…”
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Cell compatibility of a maghemite/polymer biomedical nanoplatform
Published in Toxicology in vitro (01-08-2015)“…•Toxicity is mostly determined by the amount of polymer uptake, independently of size effects.•Internalization occurs through clathrin-dependent…”
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Novel Antifouling Coatings by Zwitterionic Silica Grafting on Glass Substrates
Published in Langmuir (06-02-2024)“…Zwitterionic silica coatings for surface functionalization are greatly prominent because of their simple and fast preparation, high availability, and effective…”
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Periodic mesoporous ionosilica nanoparticles for dual cancer therapy: Two-photon excitation siRNA gene silencing in cells and photodynamic therapy in zebrafish embryos
Published in International journal of pharmaceutics (25-06-2023)“…[Display omitted] Photodynamic therapy (PDT) and photochemical internalization (PCI) are two methods that use light to provoke cell death or disturbance of…”
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