Search Results - "Ali, Hany S. M"
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Hydrocortisone nanosuspensions for ophthalmic delivery: A comparative study between microfluidic nanoprecipitation and wet milling
Published in Journal of controlled release (20-01-2011)“…Recently, drug nanosuspensions have shown a potential for ophthalmic delivery. In this study, a hydrocortisone (HC) nanosuspension (NS) was developed using…”
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Nanoparticles of Thiolated Xanthan Gum for the Oral Delivery of Miconazole Nitrate: In Vitro and In Vivo Evaluation
Published in Pharmaceutics (01-02-2024)“…The objective of this research was to develop a mucoadhesive delivery system that improves permeation for the administration of poorly absorbed oral…”
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Tadalafil-Loaded Self-Nanoemulsifying Chewable Tablets for Improved Bioavailability: Design, In Vitro, and In Vivo Testing
Published in Pharmaceutics (01-09-2022)“…This research aimed to develop innovative self-nanoemulsifying chewable tablets (SNECT) to increase oral bioavailability of tadalafil (TDL), a nearly insoluble…”
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Fabric phase sorptive extraction coupled with UPLC-ESI-MS/MS method for fast and sensitive quantitation of tadalafil in a bioequivalence study
Published in Saudi pharmaceutical journal (01-08-2022)“…The current study coupled fabric phase sorptive extraction (FPSE) with ultraperformance liquid chromatography method with electrospray ionization and tandem…”
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Boosting Tadalafil Bioavailability via Sono-Assisted Nano-Emulsion-Based Oral Jellies: Box-Behnken Optimization and Assessment
Published in Pharmaceutics (24-11-2022)“…Tadalafil (TAD) is a poorly soluble, phosphodiesterase inhibitor used to treat erectile dysfunction. The primary goal of this project was to prepare…”
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Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors
Published in International journal of pharmaceutics (22-06-2009)“…In this work, the possibility of bottom-up creation of a relatively stable aqueous hydrocortisone nanosuspension using microfluidic reactors was examined. The…”
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Alternatives to conventional suspensions for pulmonary drug delivery by nebulisers: a review
Published in Journal of pharmaceutical sciences (01-11-2011)“…This review discusses the reports of alternative dosage forms to suspension formulations of hydrophobic drugs for nebulisers. Suspensions for nebulisers,…”
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Repaglinide-Solid Lipid Nanoparticles in Chitosan Patches for Transdermal Application: Box-Behnken Design, Characterization, and In Vivo Evaluation
Published in International journal of nanomedicine (01-01-2024)“…Repaglinide (REP) is an antidiabetic drug with limited oral bioavailability attributable to its low solubility and considerable first-pass hepatic breakdown…”
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Artificial neural networks modelling the prednisolone nanoprecipitation in microfluidic reactors
Published in European journal of pharmaceutical sciences (28-06-2009)“…This study employs artificial neural networks (ANNs) to create a model to identify relationships between variables affecting drug nanoprecipitation using…”
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Engineering of solidified glyburide nanocrystals for tablet formulation via loading of carriers: downstream processing, characterization, and bioavailability
Published in International journal of nanomedicine (01-01-2019)“…Presenting poorly water-soluble drugs as nanoparticles has shown to be an effective technique in enhancing drug dissolution rate, intrinsic solubility, and…”
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Glibenclamide Nanocrystals in a Biodegradable Chitosan Patch for Transdermal Delivery: Engineering, Formulation, and Evaluation
Published in Journal of pharmaceutical sciences (01-01-2017)“…Glibenclamide (GBD) nanocrystals (D = 429 nm) were engineered by applying combined precipitation and homogenization procedures. GBD crystallinity was…”
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Tailoring the mucoadhesive and sustained release characteristics of mesalamine loaded formulations for local treatment of distal forms of ulcerative colitis
Published in European journal of pharmaceutical sciences (10-10-2016)“…Direct delivery of sustained therapeutic levels of mesalamine (MS) via rectal systems to manage distal forms of ulcerative colitis was studied. The High…”
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Dual effect biodegradable ciprofloxacin loaded implantable matrices for osteomyelitis: controlled release and osteointegration
Published in Drug development and industrial pharmacy (03-06-2018)“…Ciprofloxacin biodegradable implantable matrices (CPX-IMs) of tailored porous surfaces were fabricated by hot melt injection molding of poly-l-lactic acid…”
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Solubility of Budesonide, Hydrocortisone, and Prednisolone in Ethanol + Water Mixtures at 298.2 K
Published in Journal of chemical and engineering data (14-01-2010)“…Experimental solubilities of budesonide, hydrocortisone, and prednisolone in ethanol + water mixtures at 298.2 K are reported. The solubility of drugs was…”
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A stable hydrocortisone nanosuspension for improved dissolution: Preparation, characterization and in vitro evaluation
Published in Pakistan journal of pharmaceutical sciences (01-09-2017)“…Drug nanosuspensions have gained tremendous attraction as a platform in drug delivery. In the present work, a nanosuspension was prepared by a wet milling…”
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Evaluation of a Nanodispersion Formulation Prepared through Microfluidic Reactors for Pulmonary Delivery of Budesonide Using Nebulizers
Published in Iranian journal of pharmaceutical research : IJPR (2014)“…This study aimed to determine the aerosolization behavior of a nanodispersion of budesonide, prepared using microfluidic reactors. The size and morphology of…”
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