Search Results - "Ali, Cherie"

NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models by Charych, Deborah H, Hoch, Ute, Langowski, John L, Lee, Steve R, Addepalli, Murali K, Kirk, Peter B, Sheng, Dawei, Liu, Xiaofeng, Sims, Paul W, VanderVeen, Laurie A, Ali, Cherie F, Chang, Thomas K, Konakova, Marina, Pena, Rhoneil L, Kanhere, Rupesh S, Kirksey, Yolanda M, Ji, Chunmei, Wang, Yujun, Huang, Jicai, Sweeney, Theresa D, Kantak, Seema S, Doberstein, Stephen K

“…Aldesleukin, recombinant human IL2, is an effective immunotherapy for metastatic melanoma and renal cancer, with durable responses in approximately 10% of…”
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NKTR-181: A Novel Mu-Opioid Analgesic with Inherently Low Abuse Potential by Miyazaki, Takahiro, Choi, Irene Y, Rubas, Werner, Anand, Neel K, Ali, Cherie, Evans, Juli, Gursahani, Hema, Hennessy, Marlene, Kim, Grace, McWeeney, Daniel, Pfeiffer, Juergen, Quach, Phi, Gauvin, David, Riley, Timothy A, Riggs, Jennifer A, Gogas, Kathleen, Zalevsky, Jonathan, Doberstein, Stephen K

“…The increasing availability of prescription opioid analgesics for the treatment of pain has been paralleled by an epidemic of opioid misuse, diversion, and…”
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148 by Kirk, Peter, Addepalli, Murali, Ali, Cherie, Chang, Thomas, Huang, Jicai, Lee, Steve, Sims, Paul, VanderVeen, Laurie, Wang, Yujun, Charych, Deborah

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148 : Modulation of cytokine activity through advanced polymer conjugation by Kirk, Peter, Addepalli, Murali, Ali, Cherie, Chang, Thomas, Huang, Jicai, Lee, Steve, Sims, Paul, VanderVeen, Laurie, Wang, Yujun, Charych, Deborah

“…Cytokines have proven to be effective therapies in multiple indications including those in oncology, inflammation, and immunology. Modification of cytokines…”
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Abstract 482: Tipping the balance in the tumor microenvironment: An engineered cytokine (NKTR-214) with altered IL2 receptor binding selectivity and improved efficacy by Charych, Deborah, Lee, Steven, Addepalli, Murali, Chang, Thomas, Kirk, Peter, Konakova, Marina, Vanderveen, Laurie, Kanhere, Rupesh, Fry, Dennis, Ali, Cherie, Harrison, Stephen, Kantak, Seema, Doberstein, Stephen

“…Introduction Immunotherapy offers the potential for durable responses in a growing list of cancer indications.1 One approach towards stimulating the immune…”
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