Search Results - "Ali, Arbab S."

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation by Lemos, Henrique, Mohamed, Eslam, Huang, Lei, Ou, Rong, Pacholczyk, Gabriela, Arbab, Ali S, Munn, David, Mellor, Andrew L

“…Cytosolic DNA sensing is an important process during the innate immune response that activates the stimulator of interferon genes (STING) adaptor and induces…”
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Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade by Ouzounova, Maria, Lee, Eunmi, Piranlioglu, Raziye, El Andaloussi, Abdeljabar, Kolhe, Ravindra, Demirci, Mehmet F., Marasco, Daniela, Asm, Iskander, Chadli, Ahmed, Hassan, Khaled A., Thangaraju, Muthusamy, Zhou, Gang, Arbab, Ali S., Cowell, John K., Korkaya, Hasan

“…It is widely accepted that dynamic and reversible tumour cell plasticity is required for metastasis, however, in vivo steps and molecular mechanisms are poorly…”
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CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint by Yu, Miao, Guo, Gang, Huang, Lei, Deng, Libin, Chang, Chang-Sheng, Achyut, Bhagelu R., Canning, Madison, Xu, Ningchun, Arbab, Ali S., Bollag, Roni J., Rodriguez, Paulo C., Mellor, Andrew L., Shi, Huidong, Munn, David H., Cui, Yan

“…CD73, an ecto-5′-nucleotidase (NT5E), serves as an immune checkpoint by generating adenosine (ADO), which suppresses immune activation through the A 2A…”
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Vascular Mimicry: A Novel Neovascularization Mechanism Driving Anti-Angiogenic Therapy (AAT) Resistance in Glioblastoma by Angara, Kartik, Borin, Thaiz F., Arbab, Ali S.

“…Glioblastoma (GBM) is a hypervascular neoplasia of the central nervous system with an extremely high rate of mortality. Owing to its hypervascularity,…”
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Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization by Braun, Molly, Khan, Zenab T., Khan, Mohammad B., Kumar, Manish, Ward, Ayobami, Achyut, Bhagelu R., Arbab, Ali S., Hess, David C., Hoda, Md. Nasrul, Baban, Babak, Dhandapani, Krishnan M., Vaibhav, Kumar

“…•Inflammation is an important mediator of secondary neurological injury after TBI.•Activation of CB2R attenuates inflammation and reduces neurovascular injury…”
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Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model by Piranlioglu, Raziye, Lee, EunMi, Ouzounova, Maria, Bollag, Roni J., Vinyard, Alicia H., Arbab, Ali S., Marasco, Daniela, Guzel, Mustafa, Cowell, John K., Thangaraju, Muthushamy, Chadli, Ahmed, Hassan, Khaled A., Wicha, Max S., Celis, Esteban, Korkaya, Hasan

“…Although clinically apparent metastasis is associated with late stages of cancer development, micro-metastatic dissemination may be an early event. However,…”
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Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer by Jardim-Perassi, Bruna Victorasso, Arbab, Ali S, Ferreira, Lívia Carvalho, Borin, Thaiz Ferraz, Varma, Nadimpalli R S, Iskander, A S M, Shankar, Adarsh, Ali, Meser M, de Campos Zuccari, Debora Aparecida Pires

“…As neovascularization is essential for tumor growth and metastasis, controlling angiogenesis is a promising tactic in limiting cancer progression. Melatonin…”
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Arachidonic Acid Metabolite as a Novel Therapeutic Target in Breast Cancer Metastasis by Borin, Thaiz F, Angara, Kartik, Rashid, Mohammad H, Achyut, Bhagelu R, Arbab, Ali S

“…Metastatic breast cancer (BC) (also referred to as stage IV) spreads beyond the breast to the bones, lungs, liver, or brain and is a major contributor to the…”
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CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma by Angara, Kartik, Borin, Thaiz F., Rashid, Mohammad H., Lebedyeva, Iryna, Ara, Roxan, Lin, Ping-Chang, Iskander, ASM, Bollag, Roni J., Achyut, Bhagelu R., Arbab, Ali S.

“…BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor…”
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Self-assembling nanocomplexes by combining ferumoxytol, heparin and protamine for cell tracking by magnetic resonance imaging by Thu, Mya S, Bryant, L Henry, Coppola, Tiziana, Jordan, E Kay, Budde, Matthew D, Lewis, Bobbi K, Chaudhry, Aneeka, Ren, Jiaqiang, Varma, Nadimpalli Ravi S, Arbab, Ali S, Frank, Joseph A

“…There are currently no good ways to track human cells in vivo in a clinical setting using magnetic resonance imaging (MRI) based on superparamagnetic…”
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Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury by Vaibhav, Kumar, Braun, Molly, Alverson, Katelyn, Khodadadi, Hesam, Kutiyanawalla, Ammar, Ward, Ayobami, Banerjee, Christopher, Sparks, Tyler, Malik, Aneeq, Rashid, Mohammad H, Khan, Mohammad Badruzzaman, Waters, Michael F, Hess, David C, Arbab, Ali S, Vender, John R, Hoda, Nasrul, Baban, Babak, Dhandapani, Krishnan M

“…Traumatic brain injury (TBI) is a major cause of mortality and morbidity. Preventative measures reduce injury incidence and/or severity, yet one-third of…”
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Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo by Elashiry, Mahmoud, Elashiry, Mohamed M., Elsayed, Ranya, Rajendran, Mythily, Auersvald, Carol, Zeitoun, Rana, Rashid, Mohammad H., Ara, Roxan, Meghil, Mohamed M., Liu, Yutao, Arbab, Ali S., Arce, Roger M., Hamrick, Mark, Elsalanty, Mohammed, Brendan, Marshall, Pacholczyk, Rafal, Cutler, Christopher W.

“…Chronic bone degenerative diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. This study…”
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Proteomic Characterization, Biodistribution, and Functional Studies of Immune-Therapeutic Exosomes: Implications for Inflammatory Lung Diseases by Elashiry, Mahmoud, Elsayed, Ranya, Elashiry, Mohamed M, Rashid, Mohammad H, Ara, Roxan, Arbab, Ali S, Elawady, Ahmed R, Hamrick, Mark, Liu, Yutao, Zhi, Wenbo, Lucas, Rudolf, Vazquez, Jose, Cutler, Christopher W

“…Dendritic cell (DC)-derived exosomes (DC EXO), natural nanoparticles of endosomal origin, are under intense scrutiny in clinical trials for various…”
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HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model by Borin, Thaiz F, Shankar, Adarsh, Angara, Kartik, Rashid, Mohammad H, Jain, Meenu, Iskander, Asm, Ara, Roxan, Lebedyeva, Iryna, Korkaya, Hasan, Achyut, Bhagelu R, Arbab, Ali S

“…Distant metastasis is the primary cause of death in the majority of the cancer types. Recently, much importance has been given to tumor microenvironment (TME)…”
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20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo by Chen, Li, Ackerman, Rachel, Saleh, Mohamed, Gotlinger, Katherine H, Kessler, Michael, Mendelowitz, Lawrence G, Falck, John R, Arbab, Ali S, Scicli, A Guillermo, Schwartzman, Michal L, Yang, Jing, Guo, Austin M

“…Circulating endothelial progenitor cells (EPC) contribute to postnatal neovascularization. We identified the cytochrome P450 4A/F-20-hydroxyeicosatetraenoic…”
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Experimental study of processing of PCL (polycaprolactone)-peptides nanoparticles and its biodistribution analysis for drug delivery system by Khan, Mujibur, Yamasta, Anthony, Parvin, Mahrima, Ferdaus, Jannatul, Ahmed, Hossain, Arbab, Ali S.

“…Two types of cells targeting Peptides, TAMS-1 (CSPGAKVRCY {Lys (Biotin)}) and MDSC-peptide (Biotin {PEG4}-MEWSLEKGYTIK), were synthesized for targeting CD206…”
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Model selection for DCE-T1 studies in glioblastoma by Bagher-Ebadian, Hassan, Jain, Rajan, Nejad-Davarani, Siamak P., Mikkelsen, Tom, Lu, Mei, Jiang, Quan, Scarpace, Lisa, Arbab, Ali S., Narang, Jayant, Soltanian-Zadeh, Hamid, Paudyal, Ramesh, Ewing, James. R.

“…Dynamic contrast enhanced T1‐weighted MRI using the contrast agent gadopentetate dimeglumine (Gd‐DTPA) was performed on 10 patients with glioblastoma. Nested…”
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Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents by Frank, Joseph A, Miller, Brad R, Arbab, Ali S, Zywicke, Holly A, Jordan, E Kay, Lewis, Bobbi K, Bryant, Jr, L Henry, Bulte, Jeff W M

“…To label mammalian and stem cells by combining commercially available transfection agents (TAs) with superparamagnetic iron oxide (SPIO) magnetic resonance…”
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Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat by McFarlin, Kellie, Gao, Xiaohua, Liu, Yong Bo, Dulchavsky, Deborah S., Kwon, David, Arbab, Ali S., Bansal, Mona, Li, Yi, Chopp, Michael, Dulchavsky, Scott A., Gautam, Subhash C.

“…ABSTRACT Bone marrow‐derived mesenchymal stromal cells (BMSCs) are multipotential stem cells capable of differentiation into numerous cell types, including…”
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Major Challenges and Potential Microenvironment-Targeted Therapies in Glioblastoma by Arbab, Ali S, Rashid, Mohammad H, Angara, Kartik, Borin, Thaiz F, Lin, Ping-Chang, Jain, Meenu, Achyut, Bhagelu R

“…Glioblastoma (GBM) is considered one of the most malignant, genetically heterogeneous, and therapy-resistant solid tumor. Therapeutic options are limited in…”
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