Search Results - "Ali, Amira A. H."
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Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus
Published in Cell and tissue research (01-09-2017)“…Purinergic P2X and P2Y receptors are involved in mediating intercellular signalling via purines such as adenosine triphosphate (ATP). P2X and P2Y receptors…”
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Timing of Deep and REM Sleep Based on Fitbit Sleep Staging in Young Healthy Adults under Real-Life Conditions
Published in Brain sciences (01-03-2024)“…Sleep timing is controlled by intrinsic homeostatic and circadian components. The circadian component controls the chronotype, which is defined by the…”
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3
Effects of the Light/Dark Phase and Constant Light on Spatial Working Memory and Spine Plasticity in the Mouse Hippocampus
Published in Cells (Basel, Switzerland) (30-06-2023)“…Circadian rhythms in behavior and physiology such as rest/activity and hormones are driven by an internal clock and persist in the absence of rhythmic…”
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Radiotherapy of the Hepatocellular Carcinoma in Mice Has a Time-Of-Day-Dependent Impact on the Mouse Hippocampus
Published in Cells (Basel, Switzerland) (23-12-2022)“…Chronic liver diseases including hepatocellular carcinoma (HCC) create a state of chronic inflammation that affects the brain via the liver-brain axis leading…”
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Adult Neurogenesis under Control of the Circadian System
Published in Cells (Basel, Switzerland) (22-02-2022)“…The mammalian circadian system is a hierarchically organized system, which controls a 24-h periodicity in a wide variety of body and brain functions and…”
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Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus
Published in International journal of molecular sciences (01-08-2021)“…ATP and other nucleotides are important glio-/neurotransmitters in the central nervous system. They bind to purinergic P2X and P2Y receptors that are…”
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Sex-Dependent Effects of Bmal1-Deficiency on Mouse Cerebral Cortex Infarction in Response to Photothrombotic Stroke
Published in International journal of molecular sciences (11-10-2018)“…Stroke is a leading cause of disability and death worldwide. There is increasing evidence that occurrence of ischemic stroke is affected by circadian system…”
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Does a Red House Affect Rhythms in Mice with a Corrupted Circadian System?
Published in International journal of molecular sciences (25-02-2021)“…The circadian rhythms of body functions in mammals are controlled by the circadian system. The suprachiasmatic nucleus (SCN) in the hypothalamus orchestrates…”
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Neuroprotective and therapeutic effects of calcitriol in rotenone-induced Parkinson’s disease rat model
Published in Frontiers in cellular neuroscience (16-09-2022)“…Parkinson’s disease (PD) is the second most common neurodegenerative disease. Treatment of PD is challenging, as current treatment strategies are only…”
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Connexin30 and Connexin43 show a time-of-day dependent expression in the mouse suprachiasmatic nucleus and modulate rhythmic locomotor activity in the context of chronodisruption
Published in Cell communication and signaling (11-06-2019)“…The astroglial connexins Cx30 and Cx43 contribute to many important CNS functions including cognitive behaviour, motoric capacity and regulation of the…”
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Impact of Targeted Deletion of the Circadian Clock Gene Bmal1 in Excitatory Forebrain Neurons on Adult Neurogenesis and Olfactory Function
Published in International journal of molecular sciences (19-02-2020)“…The circadian system is an endogenous timekeeping system that synchronizes physiology and behavior with the 24 h solar day. Mice with total deletion of the…”
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The Role of Purinergic Receptors in the Circadian System
Published in International journal of molecular sciences (12-05-2020)“…The circadian system is an internal time-keeping system that synchronizes the behavior and physiology of an organism to the 24 h solar day. The master…”
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13
Premature aging of the hippocampal neurogenic niche in adult Bmal1-deficient mice
Published in Aging (Albany, NY.) (27-06-2015)“…Hippocampal neurogenesis undergoes dramatic age-related changes. Mice with targeted deletion of the clock geneBmal1 (Bmal1(-/-)) show disrupted regulation of…”
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Hepatocellular Carcinoma in Mice Affects Neuronal Activity and Glia Cells in the Suprachiasmatic Nucleus
Published in Biomedicines (27-09-2024)“…: Chronic liver diseases such as hepatic tumors can affect the brain through the liver-brain axis, leading to neurotransmitter dysregulation and behavioral…”
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15
Does timing matter in radiotherapy of hepatocellular carcinoma? An experimental study in mice
Published in Cancer medicine (Malden, MA) (01-11-2021)“…This study investigates whether a chronotherapeutic treatment of hepatocellular carcinoma (HCC) may improve treatment efficacy and mitigate side effects on…”
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Bmal1‐deficiency affects glial synaptic coverage of the hippocampal mossy fiber synapse and the actin cytoskeleton in astrocytes
Published in Glia (01-05-2020)“…Bmal1 is an essential component of the molecular clockwork, which drives circadian rhythms in cell function. In Bmal1‐deficient (Bmal1−/−) mice,…”
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P2Y2 deficiency impacts adult neurogenesis and related forebrain functions
Published in The FASEB journal (01-05-2021)“…Adult neurogenesis occurs particularly in the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricle. This…”
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P2Y 2 deficiency impacts adult neurogenesis and related forebrain functions
Published in The FASEB journal (01-05-2021)“…Adult neurogenesis occurs particularly in the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricle. This…”
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Relationship between locomotor activity rhythm and corticosterone levels during HCC development, progression, and treatment in a mouse model
Published in Journal of pineal research (01-04-2021)“…Cancer‐related fatigue (CRF) and stress are common symptoms in cancer patients and represent early side effects of cancer treatment which affect the life…”
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Deficiency of the clock gene Bmal1 affects neural progenitor cell migration
Published in Brain Structure and Function (01-01-2019)“…We demonstrate the impact of a disrupted molecular clock in Bmal1-deficient (Bmal1 −/− ) mice on migration of neural progenitor cells (NPCs). Proliferation of…”
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