Search Results - "Alhumaydhi, Fahad A"
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Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer
Published in Molecules (Basel, Switzerland) (09-07-2020)“…Epigallocatechin-3-gallate (EGCG), an active compound of green tea and its role in diseases cure and prevention has been proven. Its role in diseases…”
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Minimizing hazard impacts of soil salinity and water stress on wheat plants by soil application of vermicompost and biochar
Published in Physiologia plantarum (01-06-2021)“…Soil water and nutrient status are two of the most important factors for plant development and crop yield. Vermicompost and biochar are supposed to amend soil…”
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Berberine as a Potential Anticancer Agent: A Comprehensive Review
Published in Molecules (Basel, Switzerland) (04-12-2021)“…Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the…”
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Omicron variant (B.1.1.529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?
Published in Biomedicine & pharmacotherapy (01-10-2022)“…Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been reported worldwide. The advent of variants of concern (VOCs) raises severe…”
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Natural Small Molecules in Breast Cancer Treatment: Understandings from a Therapeutic Viewpoint
Published in Molecules (Basel, Switzerland) (27-03-2022)“…Breast cancer (BrCa) is the most common malignancy in women and the second most significant cause of death from cancer. BrCa is one of the most challenging…”
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Exploring the journey of emodin as a potential neuroprotective agent: Novel therapeutic insights with molecular mechanism of action
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants, molds, and lichens. Emodin has been used as a traditional medication…”
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Diallyl Disulfide: A Bioactive Garlic Compound with Anticancer Potential
Published in Frontiers in pharmacology (22-08-2022)“…Cancer is a life-threatening disease caused by the uncontrolled division of cells, which culminates in a solid mass of cells known as a tumor or liquid cancer…”
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Recent Developments and Anticancer Therapeutics of Paclitaxel: An Update
Published in Current pharmaceutical design (01-01-2022)“…Plants are a source of diverse classes of secondary metabolites with anticancer properties. Paclitaxel (Taxol) is an anticancer drug isolated from various…”
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Potential Therapeutic Targets of Resveratrol, a Plant Polyphenol, and Its Role in the Therapy of Various Types of Cancer
Published in Molecules (Basel, Switzerland) (21-04-2022)“…Cancer is among the most prominent causes of mortality worldwide. Different cancer therapy modes employed, including chemotherapy and radiotherapy, have been…”
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Risk factors of SARS-CoV-2 infection in cancer patients pre- and post-vaccination
Published in PloS one (09-08-2022)“…Background Severe complications from COVID-19 and poor responses to SARS-CoV-2 vaccination were commonly reported in cancer patients compared to those without…”
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Mechanistic Insight into Binding of Huperzine A with Human Serum Albumin: Computational and Spectroscopic Approaches
Published in Molecules (Basel, Switzerland) (25-01-2022)“…Human serum albumin (HSA) is the most abundant protein in plasma synthesized by the liver and the main modulator of fluid distribution between body…”
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Nanomedicines in the Management of Alzheimer's Disease: Current View and Future Prospects
Published in Frontiers in aging neuroscience (08-07-2022)“…Alzheimer's disease (AD) is a kind of dementia that creates serious challenges for sufferers' memory, thinking, and behavior. It commonly targeting the aging…”
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Role of Th17 and IL-17 Cytokines on Inflammatory and Auto-immune Diseases
Published in Current pharmaceutical design (01-01-2023)“…The IL-17 (interleukin 17) family consists of six structurally related pro-inflammatory cytokines, namely IL-17A to IL-17F. These cytokines have garnered…”
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Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce—A Comprehensive Review
Published in Antioxidants (13-06-2022)“…Lettuce is one of the most famous leafy vegetables worldwide with lots of applications from food to other specific uses. There are different types in the…”
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Can the SARS-CoV-2 Omicron Variant Confer Natural Immunity against COVID-19?
Published in Molecules (Basel, Switzerland) (29-03-2022)“…The coronavirus disease 2019 (COVID-19) pandemic is still ongoing, with no signs of abatement in sight. The severe acute respiratory syndrome coronavirus 2…”
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In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia
Published in Scientific reports (21-10-2022)“…Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study, bioinformatics analyses were conducted to identify possible pathogenic…”
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Unlocking potential inhibitors for Bruton's tyrosine kinase through in-silico drug repurposing strategies
Published in Scientific reports (17-10-2023)“…Bruton's tyrosine kinase (BTK) is a non-receptor protein kinase that plays a crucial role in various biological processes, including immune system function and…”
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Mechanistic Insight and Possible Mechanism of Seizure in Covid-19: The Nuances and Focal Points
Published in CNS & neurological disorders drug targets (01-01-2023)“…Coronavirus disease 2019 (COVID-19) is a primary respiratory disease with an alarming impact worldwide. COVID-19 is caused by severe acute respiratory syndrome…”
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Bioactive Phytoconstituents as Potent Inhibitors of Tyrosine-Protein Kinase Yes (YES1): Implications in Anticancer Therapeutics
Published in Molecules (Basel, Switzerland) (10-05-2022)“…Tyrosine-protein kinase Yes (YES1) belongs to the Tyrosine-protein kinase family and is involved in several biological activities, including cell survival,…”
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Phytotherapeutic options for the treatment of epilepsy: pharmacology, targets, and mechanism of action
Published in Frontiers in pharmacology (24-05-2024)“…Epilepsy is one of the most common, severe, chronic, potentially life-shortening neurological disorders, characterized by a persisting predisposition to…”
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