Search Results - "Alhosin, M."

In vitro cytotoxicity of curcuminoids against head and neck cancer HNO97 cell line by Almalki, Z., Algregri, M., Alhosin, M., Alkhaled, M., Damiati, S., Zamzami, M. A.

“…Abstract Oral squamous cell carcinoma (OSCC) is a malignant tumour of Head and Neck Cancer (HNC). The recent therapeutic approaches used to treat cancer have…”
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The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression by Achour, M, Jacq, X, Rondé, P, Alhosin, M, Charlot, C, Chataigneau, T, Jeanblanc, M, Macaluso, M, Giordano, A, Hughes, A D, Schini-Kerth, V B, Bronner, C

“…Inverted CCAAT box-binding protein of 90 kDa (ICBP90) is over-expressed in several types of cancer, including breast, prostate and lung cancers. In search for…”
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THE EPA:DHA 6:1-EVOKED ENDOTHELIUM-DEPENDENT NO-MEDIATED RELAXATION IN THE CORONARY ARTERY INVOLVES A COPPER-DEPENDENT PRO-OXIDANT RESPONSE TRIGGERING THE PI3-KINASE/AKT-MEDIATED ACTIVATION OF ENOS by Zgheel, F.A, Alhosin, M, Rashid, S, Auger, C, Schini-Kerth, V.B

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1036 POSTER Thymoquinone-induced UHRF1 Ubiquitination is a Key Event for Challenging Apoptosis in Cancer Cells by Alhosin, M, Ibrahim, A, Boukhari, A, Sharif, T, Gies, J.R, Müller, C.D, Schini-Kerth, V.B, Bronner, C

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1026 POSTER Antiproliferative and Apoptotic Effects of Black Currant Juice (Ribes Nigrum) on Lymphoblastic Leukemia Cells by Sharif, T, Alhosin, M, Etienne-Selloum, N, Auger, C, Bronner, C, Fuhrmann, G, Schini-Kerth, V.B

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9206 POSTER Redox-sensitive P73-related Pro-apoptotic Effect of the Polyphenolic-rich Aronia Melanocarpa Juice on Human Acute Lymphoblastic Leukemia Cells by Sharif, T, Alhosin, M, Auger, C, Minker, C, Etienne-Selloum, N, Bories, P, Bronner, C, Gronemeyer, H, Fuhrmann, G, Schini-Kerth, V.B

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In vitro cytotoxicity of curcuminoids against head and neck cancer HNO97 cell line/ Citotoxicidade in vitro de curcuminoides contra a linhagem de celulas HNO97 de cancer de cabeca e pescoco by Almalki, Z, Algregri, M, Alhosin, M, Alkhaled, M, Damiatia, S, Zamzami, M.A

“…Oral squamous cell carcinoma (OSCC) is a malignant tumour of Head and Neck Cancer (HNC). The recent therapeutic approaches used to treat cancer have adverse…”
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Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1 by Alhosin, Mahmoud, Abusnina, Abdurazzag, Achour, Mayada, Sharif, Tanveer, Muller, Christian, Peluso, Jean, Chataigneau, Thierry, Lugnier, Claire, Schini-Kerth, Valérie B., Bronner, Christian, Fuhrmann, Guy

“…The salvage anti-tumoral pathway which implicates the p53-related p73 gene is not yet fully characterized. We therefore attempted to identify the up- and…”
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Epigallocatechin-3-gallate up-regulates tumor suppressor gene expression via a reactive oxygen species-dependent down-regulation of UHRF1 by Achour, Mayada, Mousli, Marc, Alhosin, Mahmoud, Ibrahim, Abdulkhaleg, Peluso, Jean, Muller, Christian D., Schini-Kerth, Valérie B., Hamiche, Ali, Dhe-Paganon, Sirano, Bronner, Christian

“…► EGCG down-regulated UHRF1 and DNMT1 expressions in jurkat cells. ► Down-regulation of UHRF1 enhanced expression of p16INK4A and p73. ► UHRF1 over-expression…”
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Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties by Alhosin, Mahmoud, Sharif, Tanveer, Mousli, Marc, Etienne-Selloum, Nelly, Fuhrmann, Guy, Schini-Kerth, Valérie B, Bronner, Christian

“…Over-expressed in numerous cancers, Ubiquitin-like containing PHD Ring Finger 1 (UHRF1, also known as ICBP90 or Np95) is characterized by a SRA domain (Set and…”
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Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway by Alhosin, Mahmoud, León-González, Antonio J., Dandache, Israa, Lelay, Agnès, Rashid, Sherzad K., Kevers, Claire, Pincemail, Joël, Fornecker, Luc-Matthieu, Mauvieux, Laurent, Herbrecht, Raoul, Schini-Kerth, Valérie B.

“…Defect in apoptosis has been implicated as a major cause of resistance to chemotherapy observed in B cell chronic lymphocytic leukaemia (B CLL). This study…”
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Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts by Alhosin, Mahmoud, Ibrahim, Abdulkhaleg, Boukhari, Abdelaziz, Sharif, Tanveer, Gies, Jean-Pierre, Auger, Cyril, Schini-Kerth, Valérie B.

“…Summary The microtubule-targeting agents derived from natural products, such as vinca- alkaloids and taxanes are an important family of efficient anti-cancer…”
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The EPA:DHA 6:1-evoked endothelium-dependent NO-mediated relaxation in the coronary artery involves a copper-dependent pro-oxidant response triggering the PI3-kinase/Akt-mediated activation of eNOS by Zgheel, F., Alhosin, M., Rashid, S., Auger, C., Schini-Kerth, V. B.

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UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity by Achour, Mayada, Fuhrmann, Guy, Alhosin, Mahmoud, Rondé, Philippe, Chataigneau, Thierry, Mousli, Marc, Schini-Kerth, Valérie B., Bronner, Christian

“…Tat-interactive protein, 60 kDa (Tip60) is a histone acetyltransferase with specificity toward lysine 5 of histone H2A (H2AK5) and plays multiple roles in…”
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Red wine polyphenols cause growth inhibition and apoptosis in acute lymphoblastic leukaemia cells by inducing a redox-sensitive up-regulation of p73 and down-regulation of UHRF1 by Sharif, Tanveer, Auger, Cyril, Alhosin, Mahmoud, Ebel, Claudine, Achour, Mayada, Étienne-Selloum, Nelly, Fuhrmann, Guy, Bronner, Christian, Schini-Kerth, Valérie B

“…Abstract Several epidemiological studies suggest that a diet rich in fruits and vegetables, which contain high levels of polyphenols, is associated with a…”
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Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells: role of PI3-kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a by Alhosin, Mahmoud, Anselm, Eric, Rashid, Sherzad, Kim, Jong Hun, Madeira, Socorro Vanesca Frota, Bronner, Christian, Schini-Kerth, Valérie B

“…The vascular protective effect of grape-derived polyphenols has been attributable, in part, to their direct action on blood vessels by stimulating the…”
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Aronia melanocarpa juice induces a redox-sensitive p73-related caspase 3-dependent apoptosis in human leukemia cells by Sharif, Tanveer, Alhosin, Mahmoud, Auger, Cyril, Minker, Carole, Kim, Jong-Hun, Etienne-Selloum, Nelly, Bories, Pierre, Gronemeyer, Hinrich, Lobstein, Annelise, Bronner, Christian, Fuhrmann, Guy, Schini-Kerth, Valérie B

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Limoniastrum guyonianum aqueous gall extract induces apoptosis inhuman cervical cancer cells involving p16INK4A re-expression related to UHRF1 and DNMT1 down-regulation by Krifa, M., Alhosin, M., Muller, C.D., Gies, J.P., Chekir-Ghedira, L., Ghedira, K., Mely, Y., Bronner, C., Mousli, M.

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The interaction of the SRA domain of ICBP90 with a novel domain of DNMT 1 is involved in the regulation of VEGF gene expression by Achour, M, Jacq, X, Ronde, P, Alhosin, M, Charlot, C, Chataigneau, T, Jeanblanc, M, Macaluso, M, Giordano, A, Hughes, A.D, Schini-Kerth, V.B, Bronner, C

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