Search Results - "Alhiyari, Yazeed"

Metabolic differences in breast cancer stem cells and differentiated progeny by Vlashi, Erina, Lagadec, Chann, Vergnes, Laurent, Reue, Karen, Frohnen, Patricia, Chan, Mabel, Alhiyari, Yazeed, Dratver, Milana Bochkur, Pajonk, Frank

“…In general, tumor cells display a more glycolytic phenotype compared to the corresponding normal tissue. However, it is becoming increasingly clear that tumors…”
Get full text

Label-free, real-time detection of perineural invasion and cancer margins in a murine model of head and neck cancer surgery by Tam, Kenric, Alhiyari, Yazeed, Huang, Shan, Han, Albert, Stafsudd, Oscar, Shori, Ramesh, John, Maie St

“…Surgical management of head and neck cancer requires a careful balance between complete resection of malignancy and preservation of function. Surgeons must…”
Get full text

Modular polymer platform as a novel approach to head and neck cancer therapy by Alhiyari, Yazeed, Shao, Jundong, Han, Albert Y., Miller, Amanda, Krane, Jeffrey F., Luff, Marie, Momcilovic, Milica, Shackelford, David, Gu, Zhen, John, Maie A. St

“…Head and neck cancer is the sixth most common cancer in the world, with more than 300,000 deaths attributed to the disease annually. Aggressive surgical…”
Get full text

Radiation-Induced Notch Signaling in Breast Cancer Stem Cells by Lagadec, Chann, PhD, Vlashi, Erina, PhD, Alhiyari, Yazeed, MS, Phillips, Tiffany M., PhD, Bochkur Dratver, Milana, Pajonk, Frank, MD, PhD

“…Purpose To explore patterns of Notch receptor and ligand expression in response to radiation that could be crucial in defining optimal dosing schemes for…”
Get full text

Objective Assessment of Porcine Voice Acoustics for Laryngeal Surgical Modeling by Schlegel, Patrick, Wong, Kirsten, Aker, Mamdouh, Alhiyari, Yazeed, Long, Jennifer

“…Pigs have become important animal models in voice research. Several objective parameters exist to characterize the pig voice, but it is not clear which of them…”
Get full text

Anticancer effects of thymoquinone in head and neck squamous cell carcinoma: A scoping review by Kwan, Kera, Han, Albert Y., Mukdad, Laith, Barragan, Frida, Selim, Omar, Alhiyari, Yazeed, St. John, Maie

“…Objective Thymoquinone (TQ), the active constituent of Nigella sativa, has been shown to have anticancer effects in head and neck squamous cell carcinoma…”
Get full text

Nigella sativa oil mitigates xerostomia and preserves salivary function in radiotherapy‐treated mice by Luff, Marie, Evans, Lauran, Hiyari, Sarah, Kwan, Kera, Cameron, Brian, Miller, Amanda, St. John, Maie, Alhiyari, Yazeed

“…Objective This study aimed to assess if Nigella sativa oil (NSO), a health supplement containing thymoquinone as a major component, can act as a protective…”
Get full text

A 22‐year single institution review of 119 cases of salivary duct carcinoma by Han, Ethan J., Mukdad, Laith A., Alhiyari, Yazeed, Nakhla, Morcos N., Sajed, Dipti P., St. John, Maie A.

“…Objective Salivary duct carcinoma (SDC) is a rare and aggressive salivary gland malignancy. Herein, we present the largest single‐institution review of SDC to…”
Get full text

A xenograft study of human adipose stromal cell‐based vocal fold mucosal replacement in rabbits by Tran, Eric K., Alhiyari, Yazeed, Juarez, Kevin, Gowda, Bhavani Shankara, Schrader, Feng, Sajed, Dipti P., Long, Jennifer L.

“…Objectives Vocal fold (VF) scarring, manifested by increased collagen, decreased glycosaminoglycans (GAGs), and disrupted elastic fibers, remains a negative…”
Get full text

The RNA‐Binding Protein Musashi‐1 Regulates Proteasome Subunit Expression in Breast Cancer‐ and Glioma‐Initiating Cells by Lagadec, Chann, Vlashi, Erina, Frohnen, Patricia, Alhiyari, Yazeed, Chan, Mabel, Pajonk, Frank

“…Cancer stem cells (CSCs) or tumor‐initiating cells, similar to normal tissue stem cells, rely on developmental pathways, such as the Notch pathway, to maintain…”
Get full text

Real-Time Intraoperative Detection of Margins for Oral Cavity Squamous Cell Carcinoma by Tam, Kenric, Huang, Shan, Mukdad, Laith, Alhiyari, Yazeed, Krane, Jeffrey, Shori, Ramesh, Stafsudd, Oscar, St John, Maie

“…Obtaining negative surgical cancer margins is the strongest predictor for the long-term survival of oral cavity squamous cell carcinoma patients. To verify…”
Get full text

Cell‐Based Outer Vocal Fold Replacement Both Treats and Prevents Vocal Fold Scarring in Rabbits by Santuray, Rodell, Schlegel, Patrick, Zhang, Zhaoyan, Reddy, Neha, Alhiyari, Yazeed, Long, Jennifer L.

“…Objective Numerous pharmacological and cell‐based treatments have shown promise in preventing vocal fold (VF) scarring when applied at the time of injury. A…”
Get full text

A Tool to Locate Parathyroid Glands Using Dynamic Optical Contrast Imaging by Hu, Yong, Han, Albert Y., Huang, Shan, Pellionisz, Peter, Alhiyari, Yazeed, Krane, Jeffrey F., Shori, Ramesh, Stafsudd, Oscar, St. John, Maie A.

“…Objectives/Hypothesis Identification of parathyroid glands and adjacent tissues intraoperatively can be quite challenging because of their small size, variable…”
Get full text

Abstract B013: Development of oropharyngeal tumor organoids for disease modeling and high throughput drug screening by Bommakanti, Krishna K., Lin, Luda, Alhiyari, Yazeed, Sannajust, Andreanne, Mo, Brandon, Evans, Lauran, Tebon, Peyton, John, Maie St, Soragni, Alice

“…Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with approximately 550,000 new cases diagnosed each year. The…”
Get full text

Ex vivo hypercellular parathyroid gland differentiation using dynamic optical contrast imaging (DOCI) by Huang, Shan, Alhiyari, Yazeed, Hu, Yong, Tam, Kenric, Han, Albert Y, Krane, Jeffrey F, Shori, Ramesh, St John, Maie A, Stafsudd, Oscar

“…Primary hyperparathyroidism, often caused by a single adenoma (80-85%) or four-gland hyperplasia (10-15%), can lead to elevated parathyroid hormone (PTH)…”
Get full text

Abstract 224: Combining functional precision medicine and radiotherapy with bio-printed organoids in head and neck squamous cell carcinoma by Lin, Luda, Bommakanti, Krishna K., Sannajust, Andreanne V., Alhiyari, Yazeed, Mo, Brandon, Evans, Lauran, Tebon, Peyton, St. John, Maie, Soragni, Alice

“…Abstract The study aims to establish a high throughput ex vivo organoid-based drug screening platform for head and neck squamous cell carcinoma (HNSCC) to…”
Get full text

Abstract 1834: Cholinergic nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs by Darragh, Laurel B., Pham, Tiffany T., Knitz, Michael M., Nguyen, Alexander, Mukdad, Laith A., Alhiyari, Yazeed, John, Maie St, Karam, Sana D.

“…Abstract Perineural invasion (PNI) and nerve density within the tumor microenvironment (TME) have long been associated with worse outcomes in head and neck…”
Get full text

Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs by Darragh, Laurel B, Nguyen, Alexander, Pham, Tiffany T, Idlett-Ali, Shaquia, Knitz, Michael W, Gadwa, Jacob, Bukkapatnam, Sanjana, Corbo, Sophia, Olimpo, Nicholas A, Nguyen, Diemmy, Van Court, Benjamin, Neupert, Brooke, Yu, Justin, Ross, Richard B, Corbisiero, Michaele, Abdelazeem, Khalid N M, Maroney, Sean P, Galindo, David C, Mukdad, Laith, Saviola, Anthony, Joshi, Molishree, White, Ruth, Alhiyari, Yazeed, Samedi, Von, Van Bokhoven, Adrie, St John, Maie, Karam, Sana D

“…Perineural invasion (PNI) and nerve density within the tumor microenvironment (TME) have long been associated with worse outcomes in head and neck squamous…”
Get more information

The Combinational Effects of Gamma Secretase Inhibition and Radiation on the Cancer Stem Cell Population in Glioblastoma by Alhiyari, Yazeed M

“…Gamma secretase (GS) is an intramembraneous protease that cleaves over 91 different membrane substrates. GS is responsible for the final S3 cleavage of the…”
Get full text

The Combinational Effects of Gamma Secretase Inhibition and Radiation on the Cancer Stem Cell Population in Glioblastoma by Alhiyari, Yazeed M

“…Gamma secretase (GS) is an intramembraneous protease that cleaves over 91 different membrane substrates. GS is responsible for the final S3 cleavage of the…”
Get full text