Search Results - "Alhenc Gelas, M"

Diagnostic score for heparin‐induced thrombocytopenia after cardiopulmonary bypass by Lillo‐Le Louet, A., Boutouyrie, P., Alhenc‐Gelas, M., Le Beller, C., Gautier, I., Aiach, M., Lasne, D.

“…Heparin‐induced thrombocytopenia (HIT) occurs in nearly 3% of patients treated with heparin after cardiopulmonary bypass (CPB). HIT carries a risk of severe…”
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Influence of natural SERPINC1 mutations on ex vivo thrombin generation by ALHENC‐GELAS, M., CANONICO, M., PICARD, V.

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Protein S inherited qualitative deficiency: novel mutations and phenotypic influence by ALHENC‐GELAS, M., CANONICO, M., MORANGE, P. E., EMMERICH, J.

“…Background: Only a few mutations associated with qualitative protein S deficiency have already been described. Sensitivity and specificity for type II PROS1…”
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Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives by Alhenc‐Gelas, M., Plu‐Bureau, G., Guillonneau, S., Kirzin, J.‐M., Aiach, M., Ochat, N., Scarabin, P.‐Y.

“…Oral contraceptive (OC) use is associated with an increased risk of venous thromboembolism. Previous data reported higher thrombotic risk in women using…”
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The factor II G20210A gene polymorphism, but not factor V Arg506Gln, is associated with peripheral arterial disease: results of a case–control study by Reny, J‐L., Alhenc‐Gelas, M., Fontana, P., Bissery, A., Julia, P. L., Fiessinger, J‐N., Aiach, M., Emmerich, J.

“…Background: The FIIG20210A polymorphism has been associated with arterial wall thickness and atherothrombotic diseases in selected subgroups. The FVArg506Gln…”
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Genetic variation at the estrogen receptor α locus in relation to venous thromboembolism risk among postmenopausal women by STRACZEK, C., ALHENC‐GELAS, M., AUBRY, M. L., SCARABIN, P.‐Y

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Poor performance of albumin or protein-adjusted plasma calcium to diagnose dyscalcemia in hospitalized patients: A confirmatory study in a general internal medicine department by Alhenc-Gelas, M., Lefevre, G., Bachmeyer, C., M'Bappe, P., Ouahabi, S., Grateau, G., Letavernier, E., Steichen, O.

“…Hypo- and hypercalcemia are common and some causes require urgent diagnosis and treatment. Measurement of ionized calcium is the reference test to diagnose…”
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Two new antithrombin variants support a role for K114 and R13 in heparin binding by Picard, V., Susen, S., Bellucci, S., Aiach, M., Alhenc‐Gelas, M.

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P497 DIRECT SEQUENCING OF PROTEIN-C AND -S GENES IN PATIENTS WITH BUDD–CHIARI SYNDROME (BCS), PORTAL-VEIN THROMBOSIS (PVT) AND OBLITERATIVE-PORTAL-VENOPATHY (OPV) AND SUSPICION OF INHERITED PROTEIN-C OR -S DEFICIENCY by Plessier, A, Elkrief, L, Rautou, P.E, Deraucourt, E, Goria, O, Zekrini, K, Boudaoud, L, Valla, D, Alhenc Gelas, M

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Venous Thrombosis in Older People: Prevalence of the Factor V Gene Mutation Q506 by André, E., Siguret, V., Alhenc-Gelas, M., Saint-Jean, O., Gaussem, P.

“…OBJECTIVES: Old age is usually considered to be a risk factor for venous thromboembolism, in conjunction with other factors such as heart failure, major…”
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The effects of transdermal and oral estrogen/progesterone regimens on free and total protein S in postmenopausal women by Marque, V, Alhenc-Gelas, M, Plu-Bureau, G, Oger, E, Scarabin, P Y

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Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency by Pintao, Maria C, Garcia, A. A, Borgel, D, Alhenc-Gelas, M, Spek, C. A, de Visser, M. C. H, Gandrille, S, Reitsma, Pieter H

“…Hereditary protein S (PS) deficiency is an autosomal disorder caused by mutations in the PS gene (PROS1). Conventional PCR-based mutation detection identifies…”
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Protein C concentrates in a neonate with a cerebral venous thrombosis due to heterozygous type 1 protein C deficiency by Tardy-Poncet, B, Rayet, I, Damon, G, Alhenc-Gelas, M, Dutour, N, Lavocat, M P

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Skin necrosis during long-term fluindione treatment revealing protein C deficiency by Merklen-Djafri, C, Mazurier, I, Samama, M-M, Alhenc-Gelas, M, Tortel, M-C, Cribier, B, Roth, B, Batard, M-L

“…Cutaneous necrosis is a rare complication of vitamin K antagonist therapy. It presents as cutaneous hemorrhagic necrosis and usually occurs at the start of…”
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Novel human pathological mutations. Gene symbol: PROS1. Disease: Protein S deficiency by Pintao, Maria, Garcia, A A, Borgel, D, Alhenc-Gelas, M, Spek, C A, de Visser, M C H, Gandrille, S, Reitsma, P H

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Venous thromboembolic disease: risk factors and laboratory investigation by Alhenc-Gelas, M, Aiach, M, de Moerloose, P

“…The etiology of venous thromboembolic disease has been the subject of several recent discoveries, particularly on genetic predisposing factors. The laboratory…”
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Incidence of Activated Protein C Resistance Caused by the ARG 506 GLN Mutation in Factor V in 113 Unrelated Symptomatic Protein C-Deficient Patients by Gandrille, S., Greengard, J.S., Alhenc-Gelas, M., Juhan-Vague, I., Abgrall, J.F., Jude, B., Griffin, J.H., Aiach, M.

“…Because multiple risk factors in one patient may increase the clinical expression of thrombophilia, we assessed the presence in protein C-deficient patients of…”
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A rapid screening method for the factor V Arg506-->Gln mutation by Gandrille, S, Alhenc-Gelas, M, Aiach, M

“…This study compared a rapid method to detect the nucleotide mutation 1691 G-->A, responsible for the factor V Arg506-->Gln substitution, with a previously…”
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Protein C and protein S deficiencies by Aiach, M, Borgel, D, Gaussem, P, Emmerich, J, Alhenc-Gelas, M, Gandrille, S

“…The protein C (PC) pathway, with its cofactor protein S (PS), is an important natural antithrombotic mechanism. Both PC and PS deficiencies have been…”
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Impact des estrogènes endogènes et de leurs récepteurs sur le risque artériel ischémique chez les femmes ménopausées : l’étude cas-cohorte des 3 Cités by Scarabin-Carré, V, Brailly-Tabard, S, Ancelin, M.L, Gaussem, P, Alhenc-Gelas, M, Guiochon-Mantel, A, Canonico, M, Scarabin, P.Y

“…Contexte Des travaux récents ont suggéré que des concentrations élevées d’estrogènes endogènes augmentaient le risque de maladies artérielles ischémiques chez…”
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