Search Results - "Alhasan, Bashar A"

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    The mTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy by Alhasan, Bashar A, Gordeev, Sergei A, Knyazeva, Aleksandra R, Aleksandrova, Kseniia V, Margulis, Boris A, Guzhova, Irina V, Suvorova, Irina I

    Published in Membranes (Basel) (07-11-2021)
    “…Currently, the success of targeted anticancer therapies largely depends on the correct understanding of the dormant state of cancer cells, since it is…”
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    Journal Article
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    The upregulation of Ulk1-dependent autophagy does not require the p53 activity in mouse embryonic stem cells by Vorobev, Mikhail L., Alhasan, Bashar A., Suvorova, Irina I.

    “…Autophagy is known to play a critical role in the early stages of embryogenesis including the formation of blastocyst. The existence of p53 protein-deficient…”
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    The ubiquitin-proteasome system in the regulation of tumor dormancy and recurrence by Alhasan, Bashar A., Morozov, Alexey V., Guzhova, Irina V., Margulis, Boris A.

    “…Tumor recurrence is a mechanism triggered in sparse populations of cancer cells that usually remain in a quiescent state after strict stress and/or therapeutic…”
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    Journal Article
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    Inducible Ulk1 expression activates the p53 protein in mouse embryonic stem cells by Sutula, Gleb I., Alhasan, Bashar A., Vorobev, Mikhail L., Guzhova, Irina V., Suvorova, Irina I.

    “…Defective pluripotent cells are removed from embryos prior to differentiation, presumably due to upregulation of the p53 pathway. However, the mechanism…”
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    Journal Article