Search Results - "Alhasan, Bashar A"
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Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex
Published in Journal of experimental & clinical cancer research (25-10-2023)“…Abstract Background Cancer recurrence is regulated by a variety of factors, among which is the material of dying tumor cells; it is suggested that remaining…”
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The mTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy
Published in Membranes (Basel) (07-11-2021)“…Currently, the success of targeted anticancer therapies largely depends on the correct understanding of the dormant state of cancer cells, since it is…”
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The upregulation of Ulk1-dependent autophagy does not require the p53 activity in mouse embryonic stem cells
Published in Biochemical and biophysical research communications (07-05-2021)“…Autophagy is known to play a critical role in the early stages of embryogenesis including the formation of blastocyst. The existence of p53 protein-deficient…”
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The ubiquitin-proteasome system in the regulation of tumor dormancy and recurrence
Published in Biochimica et biophysica acta. Reviews on cancer (01-07-2024)“…Tumor recurrence is a mechanism triggered in sparse populations of cancer cells that usually remain in a quiescent state after strict stress and/or therapeutic…”
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Inducible Ulk1 expression activates the p53 protein in mouse embryonic stem cells
Published in Biochemical and biophysical research communications (05-11-2020)“…Defective pluripotent cells are removed from embryos prior to differentiation, presumably due to upregulation of the p53 pathway. However, the mechanism…”
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