Search Results - "Alharthi, Sameer"

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa by Buskin, Adriana, Zhu, Lili, Chichagova, Valeria, Basu, Basudha, Mozaffari-Jovin, Sina, Dolan, David, Droop, Alastair, Collin, Joseph, Bronstein, Revital, Mehrotra, Sudeep, Farkas, Michael, Hilgen, Gerrit, White, Kathryn, Pan, Kuan-Ting, Treumann, Achim, Hallam, Dean, Bialas, Katarzyna, Chung, Git, Mellough, Carla, Ding, Yuchun, Krasnogor, Natalio, Przyborski, Stefan, Zwolinski, Simon, Al-Aama, Jumana, Alharthi, Sameer, Xu, Yaobo, Wheway, Gabrielle, Szymanska, Katarzyna, McKibbin, Martin, Inglehearn, Chris F., Elliott, David J., Lindsay, Susan, Ali, Robin R., Steel, David H., Armstrong, Lyle, Sernagor, Evelyne, Urlaub, Henning, Pierce, Eric, Lührmann, Reinhard, Grellscheid, Sushma-Nagaraja, Johnson, Colin A., Lako, Majlinda

“…Mutations in pre-mRNA processing factors (PRPFs) cause autosomal-dominant retinitis pigmentosa (RP), but it is unclear why mutations in ubiquitously expressed…”
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Whole exome sequencing of a consanguineous family identifies the possible modifying effect of a globally rare AK5 allelic variant in celiac disease development among Saudi patients by Al-Aama, Jumana Yousuf, Shaik, Noor Ahmad, Banaganapalli, Babajan, Salama, Mohammed A, Rashidi, Omran, Sahly, Ahmed N, Mohsen, Mohammed O, Shawoosh, Harbi A, Shalabi, Hebah Ahmad, Edreesi, Mohammad Al, Alharthi, Sameer E, Wang, Jun, Elango, Ramu, Saadah, Omar I

“…Celiac disease (CD), a multi-factorial auto-inflammatory disease of the small intestine, is known to occur in both sporadic and familial forms. Together HLA…”
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The use of therapeutic drug monitoring for early identification of vedolizumab response in Saudi Arabian patients with inflammatory bowel disease by Anbarserry, Doaa, Mosli, Mahmoud, Qari, Yousef, Saadah, Omar, Bokhary, Rana, Esmat, Ahmed, Alsieni, Mohammed, Shaker, Ahmed, Elango, Ramu, Alharthi, Sameer

“…Vedolizumab is a humanized monoclonal antibody used to treat moderate-to-severe inflammatory bowel disease (IBD). The aim of the study was to assess the…”
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Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial‐Like Cells by Kamarudin, Taty Anna, Bojic, Sanja, Collin, Joseph, Yu, Min, Alharthi, Sameer, Buck, Harley, Shortt, Alex, Armstrong, Lyle, Figueiredo, Francisco C., Lako, Majlinda

“…Cornea is a clear outermost layer of the eye which enables transmission of light onto the retina. The transparent corneal epithelium is regenerated by limbal…”
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Colon-Targeted Therapy of Tacrolimus (FK506) in the Treatment of Experimentally Induced Colitis by Ali, Ahmed S, Altayari, Abid A, Khan, Lateef M, Alharthi, Sameer E, Ahmed, Osama A, El-Shitany, Nagla A, Ali, Soad S, Saadah, Omar I

“…Inflammatory bowel disease is a chronic or remitting/relapsing intestinal inflammation, which comprises Crohn's disease and ulcerative colitis (UC). Severe UC…”
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Neuroprotective Effect of Red Sea Marine Sponge Xestospongia testudinaria Extract Using In Vitro and In Vivo Diabetic Peripheral Neuropathy Models by Magadmi, Rania, Borouk, Kariman, Youssef, Diaa T. A., Shaala, Lamiaa A., Alrafiah, Aziza R., Shaik, Rasheed A., Alharthi, Sameer E.

“…Diabetic peripheral neuropathy (DPN) is a common complication of diabetes. Oxidative stress plays an important role in the pathophysiology of DPN. Red Sea…”
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Clinical Characteristics of Type 2 Diabetics Who are at High Risk for Obstructive Sleep Apnea by Alshehri, Mohammed A, Alharthi, Sameer R, Alsuwat, Ahmed A, Alswat, Khaled A

“…Obstructive sleep apnea (OSA) has been associated with insulin resistance and glucose intolerance. Recent reports have indicated that the majority of patients…”
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The effects of ursodeoxycholic acid on sepsis-induced cholestasis management in an animal model by Ainosah, Randa H., Hagras, Magda M., Alharthi, Sameer E., Saadah, Omar I.

“…الركود الصفراوي هو انخفاض في تدفق المادة الصفراء من الكبد إلى الجهاز الصفراوي. يستخدم حمض أورسودويكسيكوليك بشكل شائع لعلاج الركود الصفراوي. الهدف من الدراسة هو…”
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An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age‐Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure by Hallam, Dean, Collin, Joseph, Bojic, Sanja, Chichagova, Valeria, Buskin, Adriana, Xu, Yaobo, Lafage, Lucia, Otten, Elsje. G., Anyfantis, George, Mellough, Carla, Przyborski, Stefan, Alharthi, Sameer, Korolchuk, Viktor, Lotery, Andrew, Saretzki, Gabriele, McKibbin, Martin, Armstrong, Lyle, Steel, David, Kavanagh, David, Lako, Majlinda

“…Age‐related macular degeneration (AMD) is the most common cause of blindness, accounting for 8.7% of all blindness globally. Vision loss is caused ultimately…”
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Protective Effect of Celastrol on Gentamicin-induced Nephrotoxicity in Mice by Rajkhan, Alaa T., Esmat, Ahmed, Alharthi, Sameer E.

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Neuroprotective Effect of Red Sea Marine Sponge IXestospongia testudinaria/I Extract Using In Vitro and In Vivo Diabetic Peripheral Neuropathy Models by Magadmi, Rania, Borouk, Kariman, Youssef, Diaa T. A, Shaala, Lamiaa A, Alrafiah, Aziza R, Shaik, Rasheed A, Alharthi, Sameer E

“…Diabetic peripheral neuropathy (DPN) is a common complication of diabetes. Oxidative stress plays an important role in the pathophysiology of DPN. Red Sea…”
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Concise Review: Getting to the Core of Inherited Bone Marrow Failures by Adam, Soheir, Melguizo Sanchis, Dario, El‐Kamah, Ghada, Samarasinghe, Sujith, Alharthi, Sameer, Armstrong, Lyle, Lako, Majlinda

“…Bone marrow failure syndromes (BMFS) are a group of disorders with complex pathophysiology characterized by a common phenotype of peripheral cytopenia and/or…”
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iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors by Melguizo-Sanchis, Dario, Xu, Yaobo, Taheem, Dheraj, Yu, Min, Tilgner, Katarzyna, Barta, Tomas, Gassner, Katja, Anyfantis, George, Wan, Tengfei, Elango, Ramu, Alharthi, Sameer, El-Harouni, Ashraf A., Przyborski, Stefan, Adam, Soheir, Saretzki, Gabriele, Samarasinghe, Sujith, Armstrong, Lyle, Lako, Majlinda

“…Aplastic Anemia (AA) is a bone marrow failure (BMF) disorder, resulting in bone marrow hypocellularity and peripheral pancytopenia. Severe aplastic anemia…”
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Neuroprotective Role of Vitamin D3 Against Insulin Resistance and Diabetic Induced Memory Dysfunction in Rats by Zahrani, Yahya A. Al, Sattar, Mai A. Alim A., Alharthi, Sameer E., Alkreathy, Huda. M.

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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity by Turcot, Valérie, Lu, Yingchang, Highland, Heather M, Schurmann, Claudia, Justice, Anne E, Fine, Rebecca S, Bradfield, Jonathan P, Esko, Tõnu, Giri, Ayush, Graff, Mariaelisa, Guo, Xiuqing, Hendricks, Audrey E, Karaderi, Tugce, Lempradl, Adelheid, Locke, Adam E, Mahajan, Anubha, Marouli, Eirini, Sivapalaratnam, Suthesh, Young, Kristin L, Alfred, Tamuno, Feitosa, Mary F, Masca, Nicholas GD, Manning, Alisa K, Medina-Gomez, Carolina, Mudgal, Poorva, Ng, Maggie CY, Reiner, Alex P, Vedantam, Sailaja, Willems, Sara M, Winkler, Thomas W, Abecasis, Goncalo, Aben, Katja K, Alam, Dewan S, Alharthi, Sameer E, Allison, Matthew, Amouyel, Philippe, Asselbergs, Folkert W, Auer, Paul L, Balkau, Beverley, Bang, Lia E, Barroso, Inês, Bastarache, Lisa, Benn, Marianne, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bots, Michiel L, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Breen, Gerome, Brilliant, Murray H, Broer, Linda, Brumat, Marco, Burt, Amber A, Butterworth, Adam S, Campbell, Peter T, Cappellani, Stefania, Carey, David J, Catamo, Eulalia, Caulfield, Mark J, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Cocca, Massimiliano, Collins, Francis S, Cook, James P, Corley, Janie, Galbany, Jordi Corominas, Cox, Amanda J, Crosslin, David S, Cuellar-Partida, Gabriel, D'Eustacchio, Angela, Danesh, John, Davies, Gail, de Bakker, Paul IW, de Groot, Mark CH, de Mutsert, Renée, Deary, Ian J, Dedoussis, George, Demerath, Ellen W, den Heijer, Martin, den Hollander, Anneke I, den Ruijter, Hester M, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Drenos, Fotios, Du, Mengmeng, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F

“…Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci…”
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The effect of mitogen-activated protein kinase phosphatase-2 (mkp-2) over-expression via infection with advmkp-2 on human endothelial cell apoptosis and vascular smooth muscle cell proliferation by Alharthi, Sameer E. M

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