Search Results - "Alharbi, Metab"
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HPLC, FTIR and GC-MS Analyses of Thymus vulgaris Phytochemicals Executing In Vitro and In Vivo Biological Activities and Effects on COX-1 , COX-2 and Gastric Cancer Genes Computationally
Published in Molecules (Basel, Switzerland) (03-12-2022)“…Medicinal plants have played an essential role in the treatment of various diseases. , a medicinal plant, has been extensively used for biological and…”
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Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism
Published in Molecules (Basel, Switzerland) (28-01-2022)“…Autism spectrum disorder is a neurodevelopmental disorder marked by repetitive behaviour, challenges in verbal and non-verbal communication, poor…”
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3
An in silico approach uncovering the competency of oncolytic human adenovirus 52 for targeted breast cancer virotherapy
Published in Scientific reports (02-11-2024)“…Breast cancer remains a major health threat throughout the world specifically in women above 30 years of age however, it is rarely known to affect men as well…”
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4
Optimizing the resveratrol fragments for novel in silico hepatocellular carcinoma de novo drug design
Published in Scientific reports (28-07-2024)“…Hepatocellular carcinoma (HCC) incidence varies widely around the world and is impacted by factors such as the prevalence of chronic hepatitis B and C…”
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Author Correction: Optimizing the resveratrol fragments for novel in silico hepatocellular carcinoma de novo drug design
Published in Scientific reports (20-08-2024)Get full text
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6
Exploring the promising application of Be12O12 nanocage for the abatement of paracetamol using DFT simulations
Published in Scientific reports (28-10-2023)“…The removal of paracetamol from water is of prime concern because of its toxic nature in aquatic environment. In the present research, a detailed DFT study is…”
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Evaluation of Antimicrobial, Anticholinesterase Potential of Indole Derivatives and Unexpectedly Synthesized Novel Benzodiazine: Characterization, DFT and Hirshfeld Charge Analysis
Published in Molecules (Basel, Switzerland) (27-06-2023)“…The pharmacological effectiveness of indoles, benzoxazepines and benzodiazepines initiated our synthesis of indole fused benoxazepine/benzodiazepine…”
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Mathematical modeling for prediction of physicochemical characteristics of cardiovascular drugs via modified reverse degree topological indices
Published in The European physical journal. E, Soft matter and biological physics (04-08-2024)“…Global health concerns persist due to the multifaceted nature of heart diseases, which include lifestyle choices, genetic predispositions, and emerging…”
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Exploring the synthesis, structure, spectroscopy and biological activities of novel 4-benzylidene-1-(2-(2,4-dichloro phenyl)acetyl) thiosemicarbazide derivatives: An integrated experimental and theoretical investigation
Published in Saudi pharmaceutical journal (01-12-2023)“…[Display omitted] Novel α-amylase inhibitors play a crucial role in managing diabetes and obesity, contributing to improved public health by addressing these…”
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10
Biosynthesis and Mathematical Interpretation of Zero-Valent Iron NPs Using Nigella sativa Seed Tincture for Indemnification of Carcinogenic Metals Present in Industrial Effluents
Published in Molecules (Basel, Switzerland) (07-04-2023)“…Zero-valent iron nanoparticles (ZVI-NPs) are utilized for the indemnification of a wide range of environmental pollutants. Among the pollutants, heavy metal…”
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Synthesis, molecular structure and urease inhibitory activity of novel bis-Schiff bases of benzyl phenyl ketone: A combined theoretical and experimental approach
Published in Saudi pharmaceutical journal (01-08-2023)“…Synthesized bis-Schiff base derivatives as potent urease inhibitor their molecular docking, HOMO, LUMO to indicate the charge transfer from molecule to…”
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12
Dynamics of Choline-Containing Phospholipids in Traumatic Brain Injury and Associated Comorbidities
Published in International journal of molecular sciences (20-10-2021)“…The incidences of traumatic brain injuries (TBIs) are increasing globally because of expanding population and increased dependencies on motorized vehicles and…”
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13
Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity
Published in Molecules (Basel, Switzerland) (16-06-2022)“…Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes progressive neuromuscular atrophy, muscle wasting, weakness, and…”
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Pharmacological evaluation and phytochemical profiling of butanol extract of L. edodes with in- silico virtual screening
Published in Scientific reports (08-03-2024)“…L. edodes ( L. edodes ) is the most consumed mushroom in the world and has been well known for its therapeutic potential as an edible and medicinal candidate,…”
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The natural breakthrough: phytochemicals as potent therapeutic agents against spinocerebellar ataxia type 3
Published in Scientific reports (17-01-2024)“…There is no FDA-approved drug for neurological disorders like spinocerebellar ataxia type 3. CAG repeats mutation in the ATXN3 gene, causing spinocerebellar…”
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Structure based virtual screening and molecular simulation study of FDA-approved drugs to inhibit human HDAC6 and VISTA as dual cancer immunotherapy
Published in Scientific reports (02-09-2023)“…Cancer immunotherapy has significantly contributed to the treatment of various types of cancers mainly by targeting immune checkpoint inhibitors (ICI). Among…”
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17
Lacticaseibacillusparacasei BNCC345679 revolutionizes DSS-induced colitis and modulates gut microbiota
Published in Frontiers in microbiology (27-03-2024)“…The gut microbiota plays an important role in the disease progression of inflammatory bowel disease. Although probiotics are effective against IBD, not many…”
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Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis
Published in Scientific reports (08-01-2024)“…More than 95% of patients fall victim to primary amoebic meningoencephalitis (PAM), a fatal disease attacking the central nervous system. Naegleria fowleri , a…”
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Comprehensive computational analysis reveals YXXΦ[I/L/M/F/V] motif and YXXΦ-like tetrapeptides across HFRS causing Hantaviruses and their association with viral pathogenesis and host immune regulation
Published in Frontiers in immunology (06-10-2022)“…Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted through aerosolized excrement of rodents. The etiology of HFRS is complex…”
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Uncovering chikungunya virus-encoded miRNAs and host-specific targeted genes associated with antiviral immune responses: an integrated bioinformatics approach
Published in Scientific reports (10-08-2024)“…Chikungunya virus (CHIKV) is a single-stranded RNA virus belonging to the genus Alphavirus and is responsible for causing Chikungunya fever, a type of…”
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