Search Results - "Alharbi, Khalid K."
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Navigating Organizational Justice and Ethical Leadership: Empirical Evidence from Saudi Arabia
Published in SAGE open (01-06-2024)“…Organizational justice is influenced by interpersonal relationships in the workplace. This study investigates the moderating role of ethical leadership on the…”
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T-Cell Subsets and Interleukin-10 Levels Are Predictors of Severity and Mortality in COVID-19: A Systematic Review and Meta-Analysis
Published in Frontiers in medicine (28-04-2022)“…Many COVID-19 patients reveal a marked decrease in their lymphocyte counts, a condition that translates clinically into immunodepression and is common among…”
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Proxy molecular diagnosis from whole-exome sequencing reveals Papillon-Lefevre syndrome caused by a missense mutation in CTSC
Published in PloS one (23-03-2015)“…Papillon-Lefevre syndrome (PLS) is an autosomal recessive disorder characterised by severe early onset periodontitis and palmoplantar hyperkeratosis. A…”
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Genetic polymorphisms in paraoxonase 1 and G protein-coupled receptor 77, and the risk of glucose-6-phosphate dehydrogenase deficiency in a Saudi population
Published in Saudi medical journal (01-05-2015)“…To investigate the role of amino acid substitution variants Q192R and C698T in the development of glucose-6-phosphate dehydrogenase (G6PD) deficiency in a…”
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Screening for differentially‑expressed microRNA biomarkers in Saudi colorectal cancer patients by small RNA deep sequencing
Published in International journal of molecular medicine (01-12-2019)“…Colorectal cancer (CRC) is mostly diagnosed at late stages leading to high mortality rates due to the scarcity of efficient screening approaches exhibiting…”
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Purification and MIC analysis of antimicrobial proteins from Cucumis sativus L. seeds
Published in BMC complementary and alternative medicine (03-04-2018)“…Cucumis sativus L. (cucumber), from the family Cucurbitaceae, is a therapeutic plant with various pharmacological benefits, broadly utilized as a part of…”
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Nonsense Mutation in Coiled-Coil Domain Containing 151 Gene (CCDC151) Causes Primary Ciliary Dyskinesia
Published in Human mutation (01-12-2014)“…ABSTRACT Primary ciliary dyskinesia (PCD) is an autosomal‐recessive disorder characterized by impaired ciliary function that leads to subsequent clinical…”
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Circulating C5L2 gene polymorphism is associated with type 2 diabetes mellitus in Saudi population
Published in Molecular biology reports (01-11-2013)“…The aim of the present study was to examine the relationship between the novel single nucleotide polymorphism, 698C>T that causes an amino acid change from…”
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ABCA1 C69T gene polymorphism and risk of type 2 diabetes mellitus in a Saudi population
Published in Journal of biosciences (01-12-2013)“…Type 2 diabetes mellitus (T2DM) is a disease induced by complex interactions between environmental factors and certain genetic factors. Genetic variants in the…”
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Frequency of KLK3 gene deletions in the general population
Published in Annals of clinical biochemistry (01-07-2017)“…Background One of the kallikrein genes ( KLK3) encodes prostate-specific antigen, a key biomarker for prostate cancer. A number of factors, both genetic and…”
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Apolipoprotein C3 Gene Variants and Risk of Developing Type 2 Diabetes in Saudi Subjects
Published in Metabolic syndrome and related disorders (01-09-2015)“…Apolipoprotein C3 (ApoC3) is a major constituent of VLDL and is a modulator of triglyceride metabolism. Recent genetic studies have implicated several ApoC3…”
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Influence of Adiposity-Related Genetic Markers in a Population of Saudi Arabians Where Other Variables Influencing Obesity May Be Reduced
Published in Disease markers (01-01-2014)“…Large scale studies in Europeans have clearly identified common polymorphism affecting BMI and obesity. We undertook a genotype study to examine the impact of…”
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From a Single Whole Exome Read to Notions of Clinical Screening: Primary Ciliary Dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula
Published in Annals of human genetics (01-05-2012)“…Summary Primary ciliary dyskinesia (PCD) is a genetic disorder, usually autosomal recessive, causing early respiratory disease and later subfertility. Whole…”
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Insertion and deletion polymorphism in the alpha-2B adrenoceptor gene in pregnant women ripens gestational diabetes mellitus
Published in Saudi journal of biological sciences (01-01-2016)“…There are no earlier studies that reported the association of the 12Glu9 polymorphism in the alpha-2B adrenoceptor (ADRA2B) gene with gestational diabetes…”
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Very low PSA concentrations and deletions of the KLK3 gene
Published in Clinical chemistry (Baltimore, Md.) (01-01-2013)“…Prostate-specific antigen (PSA), a widely used biomarker for prostate cancer (PCa), is encoded by a kallikrein gene (KLK3, kallikrein-related peptidase 3)…”
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Expression of variable viruses as herpes simplex glycoprotein D and varicella zoster gE glycoprotein using a novel plasmid based expression system in insect cell
Published in Saudi journal of biological sciences (01-11-2017)“…Several prokaryotic and eukaryotic expression systems have been used for in vitro production of viruses’ proteins. However eukaryotic expression system was…”
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Association of angiotensin converting enzyme gene insertion/deletion polymorphism and familial hypercholesterolemia in the Saudi population
Published in Lipids in health and disease (01-12-2013)“…The study of the association between genotype and phenotype is of great importance for the prediction of multiple diseases and pathophysiological conditions…”
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Prevalence and functionality of paucimorphic and private MC4R mutations in a large, unselected European British population, scanned by meltMADGE
Published in Human mutation (01-03-2007)“…Identification of unknown mutations has remained laborious, expensive, and only viable for studies of selected cases. Population‐based “reference ranges” of…”
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Analysis of Potential Genomic Confounding in Genetic Association Studies and an Online Genomic Confounding Browser (GCB)
Published in Annals of human genetics (01-11-2011)“…Summary Genome‐wide association studies have transformed genetic studies of disease susceptibility, identifying many variants that may tag functional…”
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