Search Results - "Alhalaweh, Amjad"

Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability by Alhalaweh, Amjad, Alzghoul, Ahmad, Mahlin, Denny, Bergström, Christel A.S.

“…[Display omitted] Amorphous materials are inherently unstable and tend to crystallize upon storage. In this study, we investigated the extent to which the…”
Get full text

Origin of Deteriorated Crystal Plasticity and Compaction Properties of a 1:1 Cocrystal between Piroxicam and Saccharin by Chattoraj, Sayantan, Shi, Limin, Chen, Miles, Alhalaweh, Amjad, Velaga, Sitaram, Sun, Changquan Calvin

“…The 1:1 cocrystal between piroxicam and saccharin exhibits significantly deteriorated powder compaction properties compared to both coformers. The molecular…”
Get full text

Computational Predictions of Glass-Forming Ability and Crystallization Tendency of Drug Molecules by Alhalaweh, Amjad, Alzghoul, Ahmad, Kaialy, Waseem, Mahlin, Denny, Bergström, Christel A. S

“…Amorphization is an attractive formulation technique for drugs suffering from poor aqueous solubility as a result of their high lattice energy. Computational…”
Get full text

Effect of carrier particle shape on dry powder inhaler performance by Kaialy, Waseem, Alhalaweh, Amjad, Velaga, Sitaram P., Nokhodchi, Ali

“…The aim of this study was to characterise the aerosolisation properties of salbutamol sulphate (SS) from dry powder inhaler (DPI) formulations containing…”
Get full text

pH-Dependent Solubility of Indomethacin–Saccharin and Carbamazepine–Saccharin Cocrystals in Aqueous Media by Alhalaweh, Amjad, Roy, Lilly, Rodríguez-Hornedo, Naír, Velaga, Sitaram P

“…Cocrystals constitute an important class of pharmaceutical solids for their remarkable ability to modulate solubility and pH dependence of water insoluble…”
Get full text

1:1 and 2:1 Urea−Succinic Acid Cocrystals: Structural Diversity, Solution Chemistry, and Thermodynamic Stability by Alhalaweh, Amjad, George, Sumod, Boström, Dan, Velaga, Sitaram P

“…The aim of this work was to study the crystal structures of 1:1 and 2:1 urea−succinic acid (U-SA) cocrystals and to investigate the role of solution chemistry…”
Get full text

Bioavailability of indomethacin-saccharin cocrystals by Jung, Min-Sook, Kim, Jeong-Soo, Kim, Min-Soo, Alhalaweh, Amjad, Cho, Wonkyung, Hwang, Sung-Joo, Velaga, Sitaram P.

“…Objectives  Pharmaceutical cocrystals are new solid forms with physicochemical properties that appear promising for drug product development. However, the…”
Get full text

Theophylline Cocrystals Prepared by Spray Drying: Physicochemical Properties and Aerosolization Performance by Alhalaweh, Amjad, Kaialy, Waseem, Buckton, Graham, Gill, Hardyal, Nokhodchi, Ali, Velaga, Sitaram P.

“…The purpose of this work was to characterize theophylline (THF) cocrystals prepared by spray drying in terms of the physicochemical properties and inhalation…”
Get full text

Preparation of zolmitriptan–chitosan microparticles by spray drying for nasal delivery by Alhalaweh, Amjad, Andersson, Staffan, Velaga, Sitaram P.

“…The objective of this study was to use spray drying to prepare mucoadhesive dry powders of the antimigraine drug, zolmitriptan, in combination with the natural…”
Get full text

Effects of Polymer and Surfactant on the Dissolution and Transformation Profiles of Cocrystals in Aqueous Media by Alhalaweh, Amjad, Ali, Hassan Refat H, Velaga, Sitaram P

“…Capturing solubility advantages of cocrystals is of great interest, and thus to understand the mechanism by which different excipients could maintain the…”
Get full text

Identifying the intermolecular hydrogen-bonding supramolecular synthons in an indomethacin-nicotinamide cocrystal by solid-state NMR by Maruyoshi, Keisuke, Iuga, Dinu, Antzutkin, Oleg N, Alhalaweh, Amjad, Velaga, Sitaram P, Brown, Steven P

“…Two-dimensional (1)H double-quantum and (14)N-(1)H & (1)H-(13)C heteronuclear magic-angle spinning (MAS) NMR spectra recorded at natural isotopic abundance…”
Get more information

Solubility Behavior and Solution Chemistry of Indomethacin Cocrystals in Organic Solvents by Alhalaweh, Amjad, Sokolowski, Anders, Rodríguez-Hornedo, Naír, Velaga, Sitaram P

“…The main objective of this study was to investigate the solubility behavior and solution chemistry of indomethacin–saccharin (IND–SAC) cocrystals in organic…”
Get full text

Investigation of Drug Release from PEO Tablet Matrices in the Presence of Vitamin E as Antioxidant by Shojaee, Saeed, Nokhodchi, Ali, Cumming, Iain, Alhalaweh, Amjad, Kaialy, Waseem

“…The objective of this study was to investigate the influence of drug type on the release of drug from PEO matrix tablets accompanied with the impact of vitamin…”
Get more information

Voices in Molecular Pharmaceutics: Meet Dr. Amjad Alhalaweh, a Scientist Developing More Rapid Diagnostic Tests for Bacterial Infections by Alhalaweh, Amjad

Get full text

Formation of Cocrystals from Stoichiometric Solutions of Incongruently Saturating Systems by Spray Drying by Alhalaweh, Amjad, Velaga, Sitaram P

“…Spray drying is a well established technique for material processing and scale-up. This study investigated the formation of pharmaceutical cocrystals by spray…”
Get full text

Towards a More Desirable Dry Powder Inhaler Formulation: Large Spray-Dried Mannitol Microspheres Outperform Small Microspheres by Kaialy, Waseem, Hussain, Tariq, Alhalaweh, Amjad, Nokhodchi, Ali

“…ABSTRACT Purpose To investigate, for the first time, the performance of a dry powder inhaler (DPI, Aerolizer ® ) in the case of a model drug (i.e. albuterol…”
Get full text

Excipient effects on supersaturation, particle size dynamics, and thermodynamic activity of multidrug amorphous formulations by El Sayed, Mira, Alhalaweh, Amjad, Kovac, Lucia, Bergström, Christel A.S.

“…[Display omitted] Multidrug formulations enhance patient compliance and extend the life cycle of pharmaceutical products. To overcome solubility challenges for…”
Get full text

Assessment of enhancing curcumin’s solubility versus uptake on its anti-cancer efficacy by Rawas-Qalaji, Mutasem, Jagal, Jayalakshmi, Sadik, Sefeera, Said, Zafar, Ahmed, Iman Saad, Haider, Mohamed, Hussain, Zahid, Alhalaweh, Amjad

“…Curcumin (CUR) exhibits anti-inflammatory and anti-cancer activities. However, its poor solubility and bioavailability limit its therapeutic applications…”
Get full text

Data mining of solubility parameters for computational prediction of drug-excipient miscibility by Alhalaweh, Amjad, Alzghoul, Ahmad, Kaialy, Waseem

“…Abstract Computational data mining is of interest in the pharmaceutical arena for the analysis of massive amounts of data and to assist in the management and…”
Get full text

Influence of lactose carrier particle size on the aerosol performance of budesonide from a dry powder inhaler by Kaialy, Waseem, Alhalaweh, Amjad, Velaga, Sitaram P., Nokhodchi, Ali

“…The purpose of this study was to evaluate the effect of carrier particle size on properties of dry powder and its effect on dry powder inhaler (DPI)…”
Get full text