Search Results - "Alhaji Isa, Mustafa"

5-chloro-3-(2-(2,4-dinitrophenyl) hydrazono)indolin-2-one: synthesis, characterization, biochemical and computational screening against SARS-CoV-2 by Majoumo-Mbe, Felicite, Sangbong, Neba Abongwa, Tadjong Tcho, Alain, Namba-Nzanguim, Cyril T., Simoben, Conrad V., Eni, Donatus B., Alhaji Isa, Mustafa, Poli, Adi Narayana Reddy, Cassel, Joel, Salvino, Joseph M., Montaner, Luis J., Tietjen, Ian, Ntie-Kang, Fidele

“…Chemical prototypes with broad-spectrum antiviral activity are important toward developing new therapies that can act on both existing and emerging viruses…”
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Biophysical insights into the binding characteristics of bovine serum albumin with dipyridamole and the influence of molecular interaction with β cyclodextrin by Afrin, Shumaila, Rahman, Yusra, Alhaji Isa, Mustafa, Ahmed, Shahbaz, Tabish, Mohammad

“…The binding characteristic of anti-platelet drug dipyridamole has been investigated with a transport protein, serum albumin. A multi-spectroscopic approach has…”
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Elucidating the molecular interaction of serum albumin with nizatidine and the role of β-cyclodextrin: multi-spectroscopic and computational approach by Rahman, Yusra, Afrin, Shumaila, Alhaji Isa, Mustafa, Ahmed, Shahbaz, Tabish, Mohammad

“…Nizatidine is a histamine H2 receptor antagonist which act by inhibiting the production of stomach acid, thereby, finds its application in treating various…”
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Discovery of new potential triplet acting inhibitor for Alzheimer's disease via X-ray crystallography, molecular docking and molecular dynamics by Sivakumar, Maharajan, Saravanan, Kandasamy, Saravanan, Velautham, Sugarthi, Srinivasan, kumar, Shankar Madan, Alhaji Isa, Mustafa, Rajakumar, Perumal, Aravindhan, Sanmargam

“…The most common brain disorder of late life is Alzheimer's disease (AD), which is highly complicating dementia. There are several drug targets which are…”
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Pyridazine Derivatives as New Antidiabetic Agents: Synthesis, In‐Vitro α‐Amylase Inhibitory Activity, Molecular Docking and Molecular Dynamics Simulations Studies by Boukharsa, Youness, Alhaji Isa, Mustafa, Sayah, Karima, Alsalme, Ali, Oulmidi, Afaf, Shehzadi, Somia, El Abbes Faouzi, My, Karrouchi, Khalid, Ansar, M'hammed

“…This study involved the synthesis, characterization, and assessment of fourteen pyridazine analogs (designated as 1–14) to investigate their efficacy in…”
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Identification of potent inhibitors of ATP synthase subunit c (AtpE) from Mycobacterium tuberculosis using in silico approach by Isa, Mustafa Alhaji, Abubakar, Mustapha B., Mohammed, Mohammed Mustapha, Ibrahim, Muhammad Musa, Gubio, Falmata Audu

“…ATP synthase subunit c (AtpE) is an enzyme that catalyzes the production of ATP from ADP in the presence of sodium or proton gradient from Mycobacterium…”
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Molecular modelling and dynamic simulation of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) from Mycobacterium tuberculosis using in silico approach by Alhaji Isa, Mustafa, Majumdar, Rita Singh, Haider, Shazia, Kandasamy, Saravanan

“…UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) catalyses the biosynthesis of peptidoglycans in Mycobacterium tuberculosis (MTB) cell wall by adding…”
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Comparative modeling and dynamic simulation of UDP-N-acetylmuramoyl-alanine ligase (MurC) from Mycobacterium tuberculosis through virtual screening and toxicity analysis by Isa, Mustafa Alhaji

“…UDP-N-acetylmuramic-alanine ligase (MurC) is an enzyme catalyzing the addition of L-alanine to UDP-acetylmuramoyl nucleotide precursor in Mycobacterium…”
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Homology modeling and molecular dynamic simulation of UDP-N-acetylmuramoyl-l-alanine-d-glutamate ligase (MurD) from Mycobacterium tuberculosis H37Rv using in silico approach by Isa, Mustafa Alhaji

“…[Display omitted] The present study aimed to identify the prospective inhibitors of MurD, a cytoplasmic enzyme that catalyzes the addition of d-glutamate to…”
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Homology modeling and in silico toxicity assessment of potential inhibitors of cytidylate kinase from Mycobacterium tuberculosis by Isa, Mustafa Alhaji

“…Cytidylate kinase (CMK) plays a central role in the phosphorylation of ATP to nucleoside diphosphates in the purine and pyrimidine pathway in Mycobacterium…”
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Inhibition of glutathione and s-allyl glutathione on pancreatic lipase: Analysis through in vitro kinetics, fluorescence spectroscopy and in silico docking by Thayumanavan, Palvannan, Nallaiyan, Selvan, Loganathan, Chitra, Sakayanathan, Penislusshiyan, Kandasamy, Saravanan, Isa, Mustafa Alhaji

“…Inhibition of pancreatic lipase (PL) is considered one of the important therapeutic interventions against obesity. In the present study, the inhibition of…”
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Molecular docking and dynamic simulation of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) obtained from Mycobacterium tuberculosis using in silico approach by Isa, Mustafa Alhaji, Mohammed, Mohammed Mustapha

“…The UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) catalyzes the final steps of the UDP-N-acetylmuramic acid (UDPMurNAc) formation in the peptidoglycan…”
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Synthesis, crystal structure, DFT, Hirshfeld surface analysis, energy framework, docking and molecular dynamic simulations of (E)-4-(4-methylbenzyl)-6-styrylpyridazin-3(2H)-one as anticancer agent by El Kalai, Fouad, Çınar, Emine Berrin, Sert, Yusuf, Alhaji Isa, Mustafa, Lai, Chin-Hung, Buba, Fatimah, Dege, Necmi, Benchat, Noureddine, Karrouchi, Khalid

“…In this work, a novel crystal, (E)-4-(4-methylbenzyl)-6-styrylpyridazin-3(2H)-one (E-BSP) was synthesized via Knoevenagel condensation of benzaldehyde and…”
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In silico identification of potential inhibitors against shikimate dehydrogenase through virtual screening and toxicity studies for the treatment of tuberculosis by Isa, Mustafa Alhaji, Majumdar, Rita Singh, Haider, Shazia

“…The present study attempts to identify the novel inhibitors of shikimate dehydrogenase (SD), the enzyme that catalyzes the fourth reaction in the shikimate…”
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In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis by Isa, Mustafa Alhaji, Majumdhar, Rita Singh, Haider, Shazia

“…The shikimate pathway is as an attractive target because it is present in bacteria, algae, fungi, and plants but does not occur in mammals. In Mycobacterium…”
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Identification of potential inhibitors of shikimate kinase from Mycobacterium tuberculosis using in silico approach by Isa, Mustafa Alhaji, Mohammed, Mohammed Mustapha, Ibrahim, Muhammad Musa, Gubio, Falmata Audu, Buba, Fatimah, Shehzadi, Somia

“…Shikimate kinase is an enzyme that plays a crucial role in the biosynthesis of aromatic amino acids. It is integral to the fifth step of the shikimate pathway,…”
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Computer-aided drug design based on comparative modeling, molecular docking and molecular dynamic simulation of Polyphosphate kinase (PPK) from Mycobacterium tuberculosis by Alhaji Isa, Mustafa, Singh Majumdar, Rita

“…This study aimed to identify compounds that are capable of inhibiting polyphosphate kinase (PPK), the protein that shares a similar pathway with the target of…”
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