Search Results - "Alhadrami, Hani A."

Techniques for the Detection of Sickle Cell Disease: A Review by Arishi, Wjdan A., Alhadrami, Hani A., Zourob, Mohammed

“…Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin gene that leads to the production of abnormal hemoglobin called…”
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Aptamer-Based Microfluidic Electrochemical Biosensor for Monitoring Cell-Secreted Trace Cardiac Biomarkers by Shin, Su Ryon, Zhang, Yu Shrike, Kim, Duck-Jin, Manbohi, Ahmad, Avci, Huseyin, Silvestri, Antonia, Aleman, Julio, Hu, Ning, Kilic, Tugba, Keung, Wendy, Righi, Martina, Assawes, Pribpandao, Alhadrami, Hani A, Li, Ronald A, Dokmeci, Mehmet R, Khademhosseini, Ali

“…Continual monitoring of secreted biomarkers from organ-on-a-chip models is desired to understand their responses to drug exposure in a noninvasive manner. To…”
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Olive-Derived Triterpenes Suppress SARS COV-2 Main Protease: A Promising Scaffold for Future Therapeutics by Alhadrami, Hani A, Sayed, Ahmed M, Sharif, Ahmed M, Azhar, Esam I, Rateb, Mostafa E

“…SARS CoV-2 pandemic is still considered a global health disaster, and newly emerged variants keep growing. A number of promising vaccines have been recently…”
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A metabolomic approach to target antimalarial metabolites in the Artemisia annua fungal endophytes by Alhadrami, Hani A., Sayed, Ahmed M., El-Gendy, Ahmed O., Shamikh, Yara I., Gaber, Yasser, Bakeer, Walid, Sheirf, Noheir H., Attia, Eman Z., Shaban, Gehan M., Khalifa, Basma A., Ngwa, Che J., Pradel, Gabriele, Rateb, Mostafa E., Hassan, Hossam M., Alkhalifah, Dalal H. M., Abdelmohsen, Usama Ramadan, Hozzein, Wael N.

“…Fungal endophytes are a major source of anti-infective agents and other medically relevant compounds. However, their classical blinded-chemical investigation…”
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Induction of Antibacterial Metabolites by Co-Cultivation of Two Red-Sea-Sponge-Associated Actinomycetes Micromonospora sp. UR56 and Actinokinespora sp. EG49 by S Hifnawy, Mohamed, Hassan, Hossam M, Mohammed, Rabab, M Fouda, Mohamed, Sayed, Ahmed M, A Hamed, Ahmed, F AbouZid, Sameh, Rateb, Mostafa E, Alhadrami, Hani A, Abdelmohsen, Usama Ramadan

“…Liquid chromatography coupled with high resolution mass spectrometry (LC-HRESMS)-assisted metabolomic profiling of two sponge-associated actinomycetes, sp…”
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Genotoxicity and mutagenicity assessment of electronic cigarette liquids by Al-Otaibi, Hajed M, Baqasi, Aisha Ms, Alhadrami, Hani A

“…Electronic cigarettes (e-cigarettes) are often advertised as a safer alternative to traditional smoking. However, recent data suggest they may not be as safe…”
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Molecular insights and inhibitory dynamics of flavonoids in targeting Pim-1 kinase for cancer therapy by Alhadrami, Hani A, Sayed, Ahmed M, Hassan, Hossam M, Alhadrami, Albaraa H, Rateb, Mostafa E

“…Pim-1 kinase, a serine/threonine kinase, is often overexpressed in various cancers, contributing to disease progression and poor prognosis. In this study, we…”
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Bio-Guided Isolation of Antimalarial Metabolites from the Coculture of Two Red Sea Sponge-Derived Actinokineospora and Rhodococcus spp by Alhadrami, Hani A, Thissera, Bathini, Hassan, Marwa H A, Behery, Fathy A, Ngwa, Che Julius, Hassan, Hossam M, Pradel, Gabriele, Abdelmohsen, Usama Ramadan, Rateb, Mostafa E

“…Coculture is a productive technique to trigger microbes' biosynthetic capacity by mimicking the natural habitats' features principally by competition for food…”
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Anti-Inflammatory and Antioxidant Activities of Terpene- and Polyphenol-Rich Premna odorata Leaves on Alcohol-Inflamed Female Wistar Albino Rat Liver by Elmaidomy, Abeer H, Alhadrami, Hani A, Amin, Elham, Aly, Hanan F, Othman, Asmaa M, Rateb, Mostafa E, Hetta, Mona H, Abdelmohsen, Usama Ramadan, M Hassan, Hossam

“…Blanco (Lamiaceae) is an ethnomedicinal plant native to different tropical regions. Although some reports addressed their anti-inflammatory, cytotoxic, and…”
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Flavonoids as Potential anti-MRSA Agents through Modulation of PBP2a: A Computational and Experimental Study by Alhadrami, Hani A., Hamed, Ahmed A., Hassan, Hossam M., Belbahri, Lassaad, Rateb, Mostafa E., Sayed, Ahmed M.

“…Recently, the interest in plant-derived antimicrobial agents has increased. However, there are no sufficient studies dealing with their modes of action…”
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Microbial Natural Products as Potential Inhibitors of SARS-CoV-2 Main Protease (M pro ) by Sayed, Ahmed M, Alhadrami, Hani A, El-Gendy, Ahmed O, Shamikh, Yara I, Belbahri, Lassaad, Hassan, Hossam M, Abdelmohsen, Usama Ramadan, Rateb, Mostafa E

“…The main protease (M ) of the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was subjected to hyphenated pharmacophoric-based and…”
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Titanium Oxide (TiO2) Nanoparticles for Treatment of Wound Infection by Alhadrami, Hani A, Shoudri, Raniyah A.M

“…Wound infections is one of the major problems worldwide. Millions of people around the world require several medical treatments for wound infections. The…”
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Anticancer Potential of Green Synthesized Silver Nanoparticles of the Soft Coral Cladiella pachyclados Supported by Network Pharmacology and In Silico Analyses by Alhadrami, Hani A., Alkhatabi, Heba, Abduljabbar, Fahad H., Abdelmohsen, Usama Ramadan, Sayed, Ahmed M.

“…Cladiella-derived natural products have shown promising anticancer properties against many human cancer cell lines. In the present investigation, we found that…”
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A Portable Nanoprobe for Rapid and Sensitive Detection of SARS-CoV-2 S1 Protein by Alhadrami, Hani A, Suaifan, Ghadeer A R Y, Zourob, Mohammed M

“…Simple, timely, and precise detection of SARS-CoV-2 in clinical samples and contaminated surfaces aids in lowering attendant morbidity/mortality related to…”
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Deep Ensemble Model for COVID-19 Diagnosis and Classification Using Chest CT Images by Ragab, Mahmoud, Eljaaly, Khalid, Alhakamy, Nabil A, Alhadrami, Hani A, Bahaddad, Adel A, Abo-Dahab, Sayed M, Khalil, Eied M

“…Coronavirus disease 2019 (COVID-19) has spread worldwide, and medicinal resources have become inadequate in several regions. Computed tomography (CT) scans are…”
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In Silico-Based Discovery of Natural Anthraquinones with Potential against Multidrug-Resistant E. coli by Alhadrami, Hani A, Abdulaal, Wesam H, Hassan, Hossam M, Alhakamy, Nabil A, Sayed, Ahmed M

“…is a Gram-negative bacterium that causes different human infections. Additionally, it resists common antibiotics due to its outer protective membrane. Natural…”
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Neoechinulin A as a Promising SARS-CoV-2 Mpro Inhibitor: In Vitro and In Silico Study Showing the Ability of Simulations in Discerning Active from Inactive Enzyme Inhibitors by Alhadrami, Hani A., Burgio, Gaia, Thissera, Bathini, Orfali, Raha, Jiffri, Suzan E., Yaseen, Mohammed, Sayed, Ahmed M., Rateb, Mostafa E.

“…The COVID-19 pandemic and its continuing emerging variants emphasize the need to discover appropriate treatment, where vaccines alone have failed to show…”
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Bioassay-Guided Isolation, Metabolic Profiling, and Docking Studies of Hyaluronidase Inhibitors from Ravenala madagascariensis by Mohamed, Esraa M, Hetta, Mona H, Rateb, Mostafa E, Selim, Mohamed A, AboulMagd, Asmaa M, Badria, Farid A, Abdelmohsen, Usama Ramadan, Alhadrami, Hani A, Hassan, Hossam M

“…Hyaluronidase enzyme (HAase) has a role in the dissolution or disintegration of hyaluronic acid (HA) and in maintaining the heathy state of skin…”
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Biosensors: Classifications, medical applications, and future prospective by Alhadrami, Hani A.

“…Biosensors are devices that combine a biological material with a suitable platform for detection of pathogenic organisms, carcinogenic, mutagenic, and/or toxic…”
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Targeting allosteric sites of human aromatase: a comprehensive in-silico and in-vitro workflow to find potential plant-based anti-breast cancer therapeutics by Alhadrami, Hani A., Sayed, Ahmed M., Melebari, Sami A., Khogeer, Asem A., Abdulaal, Wesam H., Al-Fageeh, Mohamed B., Algahtani, Mohammad, Rateb, Mostafa E.

“…Recent findings suggested several allosteric pockets on human aromatase that could be utilised for the development of new modulators able to inhibit this…”
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