Search Results - "Alhadrami, Hani A"
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Techniques for the Detection of Sickle Cell Disease: A Review
Published in Micromachines (Basel) (05-05-2021)“…Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin gene that leads to the production of abnormal hemoglobin called…”
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Aptamer-Based Microfluidic Electrochemical Biosensor for Monitoring Cell-Secreted Trace Cardiac Biomarkers
Published in Analytical chemistry (Washington) (18-10-2016)“…Continual monitoring of secreted biomarkers from organ-on-a-chip models is desired to understand their responses to drug exposure in a noninvasive manner. To…”
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Olive-Derived Triterpenes Suppress SARS COV-2 Main Protease: A Promising Scaffold for Future Therapeutics
Published in Molecules (Basel, Switzerland) (01-05-2021)“…SARS CoV-2 pandemic is still considered a global health disaster, and newly emerged variants keep growing. A number of promising vaccines have been recently…”
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4
A metabolomic approach to target antimalarial metabolites in the Artemisia annua fungal endophytes
Published in Scientific reports (02-02-2021)“…Fungal endophytes are a major source of anti-infective agents and other medically relevant compounds. However, their classical blinded-chemical investigation…”
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Induction of Antibacterial Metabolites by Co-Cultivation of Two Red-Sea-Sponge-Associated Actinomycetes Micromonospora sp. UR56 and Actinokinespora sp. EG49
Published in Marine drugs (05-05-2020)“…Liquid chromatography coupled with high resolution mass spectrometry (LC-HRESMS)-assisted metabolomic profiling of two sponge-associated actinomycetes, sp…”
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Genotoxicity and mutagenicity assessment of electronic cigarette liquids
Published in Annals of thoracic medicine (01-07-2024)“…Electronic cigarettes (e-cigarettes) are often advertised as a safer alternative to traditional smoking. However, recent data suggest they may not be as safe…”
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Molecular insights and inhibitory dynamics of flavonoids in targeting Pim-1 kinase for cancer therapy
Published in Frontiers in pharmacology (07-10-2024)“…Pim-1 kinase, a serine/threonine kinase, is often overexpressed in various cancers, contributing to disease progression and poor prognosis. In this study, we…”
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Bio-Guided Isolation of Antimalarial Metabolites from the Coculture of Two Red Sea Sponge-Derived Actinokineospora and Rhodococcus spp
Published in Marine drugs (12-02-2021)“…Coculture is a productive technique to trigger microbes' biosynthetic capacity by mimicking the natural habitats' features principally by competition for food…”
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Anti-Inflammatory and Antioxidant Activities of Terpene- and Polyphenol-Rich Premna odorata Leaves on Alcohol-Inflamed Female Wistar Albino Rat Liver
Published in Molecules (Basel, Switzerland) (08-07-2020)“…Blanco (Lamiaceae) is an ethnomedicinal plant native to different tropical regions. Although some reports addressed their anti-inflammatory, cytotoxic, and…”
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Flavonoids as Potential anti-MRSA Agents through Modulation of PBP2a: A Computational and Experimental Study
Published in Antibiotics (Basel) (01-09-2020)“…Recently, the interest in plant-derived antimicrobial agents has increased. However, there are no sufficient studies dealing with their modes of action…”
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Microbial Natural Products as Potential Inhibitors of SARS-CoV-2 Main Protease (M pro )
Published in Microorganisms (Basel) (29-06-2020)“…The main protease (M ) of the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was subjected to hyphenated pharmacophoric-based and…”
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Titanium Oxide (TiO2) Nanoparticles for Treatment of Wound Infection
Published in Journal of pure & applied microbiology : an international research journal of microbiology (01-03-2021)“…Wound infections is one of the major problems worldwide. Millions of people around the world require several medical treatments for wound infections. The…”
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Anticancer Potential of Green Synthesized Silver Nanoparticles of the Soft Coral Cladiella pachyclados Supported by Network Pharmacology and In Silico Analyses
Published in Pharmaceutics (03-11-2021)“…Cladiella-derived natural products have shown promising anticancer properties against many human cancer cell lines. In the present investigation, we found that…”
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A Portable Nanoprobe for Rapid and Sensitive Detection of SARS-CoV-2 S1 Protein
Published in Biosensors (Basel) (11-04-2022)“…Simple, timely, and precise detection of SARS-CoV-2 in clinical samples and contaminated surfaces aids in lowering attendant morbidity/mortality related to…”
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Deep Ensemble Model for COVID-19 Diagnosis and Classification Using Chest CT Images
Published in Biology (Basel, Switzerland) (29-12-2021)“…Coronavirus disease 2019 (COVID-19) has spread worldwide, and medicinal resources have become inadequate in several regions. Computed tomography (CT) scans are…”
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In Silico-Based Discovery of Natural Anthraquinones with Potential against Multidrug-Resistant E. coli
Published in Pharmaceuticals (Basel, Switzerland) (11-01-2022)“…is a Gram-negative bacterium that causes different human infections. Additionally, it resists common antibiotics due to its outer protective membrane. Natural…”
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Neoechinulin A as a Promising SARS-CoV-2 Mpro Inhibitor: In Vitro and In Silico Study Showing the Ability of Simulations in Discerning Active from Inactive Enzyme Inhibitors
Published in Marine drugs (24-02-2022)“…The COVID-19 pandemic and its continuing emerging variants emphasize the need to discover appropriate treatment, where vaccines alone have failed to show…”
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Bioassay-Guided Isolation, Metabolic Profiling, and Docking Studies of Hyaluronidase Inhibitors from Ravenala madagascariensis
Published in Molecules (Basel, Switzerland) (08-04-2020)“…Hyaluronidase enzyme (HAase) has a role in the dissolution or disintegration of hyaluronic acid (HA) and in maintaining the heathy state of skin…”
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Biosensors: Classifications, medical applications, and future prospective
Published in Biotechnology and applied biochemistry (01-05-2018)“…Biosensors are devices that combine a biological material with a suitable platform for detection of pathogenic organisms, carcinogenic, mutagenic, and/or toxic…”
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Targeting allosteric sites of human aromatase: a comprehensive in-silico and in-vitro workflow to find potential plant-based anti-breast cancer therapeutics
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2021)“…Recent findings suggested several allosteric pockets on human aromatase that could be utilised for the development of new modulators able to inhibit this…”
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