Death and Venous Thromboembolism Analyses among Hospitalized COVID-19-Positive Patients: A Multicenter Study

Death and Venous Thromboembolism Analyses among Hospitalized COVID-19-Positive Patients: A Multicenter Study

Coagulation disorders are frequently encountered among patients infected with coronavirus disease 2019 (COVID-19), especially among admitted patients with more severe symptoms. This study aims to determine the mortality rate and incidence and risk factors for venous thromboembolism (VTE) in hospital...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical medicine Vol. 12; no. 24; p. 7624
Main Authors: Alshahrani, Asma, Almoahzieie, Abdullah, Alshareef, Hanan, Alammash, Buthinah B, Alhamidi, Sarah, Meraya, Abdulkarim M, Alshammari, Abdullah S, Ajlan, Aziza, Alghofaili, Alnajla, Alnassar, Abdullah, Alshahrani, Nada, Aldossari, Maram, Alkhaldi, Turkiah, Alwazzeh, Marwan J, Almashouf, Abdullah B, Alkuwaiti, Feras A, Alghamdi, Shrouq Hamed, Alshehri, Ohuod, Ali, Mostafa
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 01-12-2023
Subjects:
Anticoagulants
Beta blockers
Blood diseases
Body mass index
Cancer
Cardiovascular disease
Clinical medicine
Data collection
Demographic aspects
Diabetes
Heart failure
Hospitals
Hypertension
Infections
Intensive care
Ischemia
Kidney diseases
Laboratories
Liver diseases
Metabolic disorders
Mortality
Patients
Regression analysis
Risk factors
Statistical analysis
Thromboembolism
Thyroid gland
Ventilators
Saudi Arabia
Riyadh Saudi Arabia
COVID-19
SARS-CoV-2
coagulation disorders
venous thromboembolism
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Coagulation disorders are frequently encountered among patients infected with coronavirus disease 2019 (COVID-19), especially among admitted patients with more severe symptoms. This study aims to determine the mortality rate and incidence and risk factors for venous thromboembolism (VTE) in hospitalized patients with COVID-19. This retrospective observational cohort study was conducted from March to July 2020 using a hospital database. All adult patients (>18 years old) with laboratory-confirmed COVID-19 were included. Laboratory data and the real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) for SARS-CoV-2 were obtained from medical records. The mortality rate and the incidence of VTE were established as study results. A multivariate logistic regression analysis was performed to identify predictors of thrombotic events. rA total of 1024 confirmed COVID-19 patients were treated, of whom 110 (10.7%) were deceased and 58 patients (5.7%) developed VTE. Death occurred more frequently in patients older than 50 years and those admitted to the intensive care unit (ICU, 95%) and who received mechanical ventilation (62.7%). Multivariate analysis revealed that cancer patients were two times more likely to have VTE (adjusted odds ratio = 2.614; 95% CI = (1.048-6.519); = 0.039). Other chronic diseases, such as diabetes, hypertension, and chronic kidney disease, were not associated with an increased risk of VTE. One-tenth of hospitalized COVID-19 patients were deceased, and VTE was prevalent among patients with chronic conditions, such as cancer, despite anticoagulation therapy. Healthcare professionals should closely monitor individuals with a high risk of developing VTE to prevent unwanted complications.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm12247624