Search Results - "Algee, Samuel E"

Synthesis and Evaluation of Hydroxylated Polyamine Analogues as Antiproliferatives by Bergeron, Raymond J, Müller, Ralf, Huang, Guangfei, McManis, James S, Algee, Samuel E, Yao, Hua, Weimar, William R, Wiegand, Jan

“…A new means of accessing N -cyclopropylmethyl-N 11-ethylnorspermine (CPMENSPM) and the first synthesis of (2R,10S)-N 1-cyclopropylmethyl-2,10-dihydroxy-N…”
Get full text

Polyamine Analogue Antidiarrheals:  A Structure−Activity Study by Bergeron, Raymond J, Wiegand, Jan, McManis, James S, Weimar, William R, Smith, Richard E, Algee, Samuel E, Fannin, Tammy L, Slusher, Michael A, Snyder, Patti S

“…The syntheses of a group of spermine polyamine analogues and their evaluation as antidiarrheals are described. Each compound was assessed in a rodent castor…”
Get full text

Synthesis and Biological Evaluation of Naphthyldesferrithiocin Iron Chelators by Bergeron, Raymond J, Wiegand, Jan, Wollenweber, Markus, McManis, James S, Algee, Samuel E, Ratliff-Thompson, Katie

“…The synthesis and iron-clearing properties of the naphthyldesferrithiocins 2-(2‘-hydroxynaphth-1‘-yl)-Δ2-thiazoline-(4R)-carboxylic acid,…”
Get full text

The Desferrithiocin Pharmacophore by Bergeron, Raymond J, Liu, Charles Z, McManis, James S, Xia, Michael X. B, Algee, Samuel E, Wiegand, Jan

“…The (S)-desferrithiocin (DFT) skeleton is shown to be a useful pharmacophore on which to design orally effective iron chelators. While the study clearly…”
Get full text