Search Results - "Algül, Oztekin"

Exploring new 5‐Nitroimidazole Derivatives as Potent Acetylcholinesterase and Butyrylcholinesterase Enzyme Inhibitors by Gursoy, Sule, Satici, Doruk, Kuzu, Burak, Turkmenoglu, Burcin, Dilek, Esra, Algul, Oztekin

“…Discovering new compounds capable of inhibiting physiologically and metabolically significant drug targets or enzymes is of paramount importance in biological…”
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Synthesis of New Alicyclic Oxalamide Derivatives and Their Differential Immunomodulatory Activities on the Mammalian Cells by Kuzu, Burak, Ayaz, Furkan, Algul, Oztekin

“…A series of novel alicyclic oxalamide derivatives were synthesized by the reaction of the N‐alicyclic secondary amine analogs with the intermediates obtained…”
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Symmetric bis-benzoxazole-based chemicals exerted anti-inflammatory effect on danger signal LPS-stimulated macrophages by Ayaz, Furkan, Ersan, Ronak Haj, Algul, Oztekin

“…Inflammatory responses are generated against the danger molecules under normal conditions but excessive or chronic inflammation leads to tissue degeneration…”
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From Deep Learning to the Discovery of Promising VEGFR‐2 Inhibitors by Yucel, Mehmet Ali, Adal, Ercan, Aktekin, Mine Buga, Hepokur, Ceylan, Gambacorta, Nicola, Nicolotti, Orazio, Algul, Oztekin

“…Vascular endothelial growth factor receptor 2 (VEGFR‐2) stands as a prominent therapeutic target in oncology, playing a critical role in angiogenesis, tumor…”
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New chalcone derivatives as effective against SARS-CoV-2 agent by Duran, Nizami, Polat, M Fatih, Aktas, Derya Anil, Alagoz, M Abdullah, Ay, Emrah, Cimen, Funda, Tek, Erhan, Anil, Baris, Burmaoglu, Serdar, Algul, Oztekin

“…Flavonoids and related compounds, such as quercetin-based antiviral drug Gene-Eden-VIR/Novirin, inhibit the protease of severe acute respiratory syndrome…”
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Revisit to the synthesis of 1,2,3,4-tetrasubstituted pyrrole derivatives in lactic acid media as a green solvent and catalyst by Akbaslar, Dilek, Giray, E. Sultan, Algul, Oztekin

“…In this study, for the first time, lactic acid was used as a bio-based green catalyst and reaction medium for the synthesis of 1,2,3,4-tetrasubstituted pyrrole…”
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Head-to-head bisbenzazole derivatives as antiproliferative agents: design, synthesis, in vitro activity, and SAR analysis by Ersan, Ronak Haj, Alagoz, Mehmet Abdullah, Ertan-Bolelli, Tugba, Duran, Nizami, Burmaoglu, Serdar, Algul, Oztekin

“…In the present work, a series of bisbenzazole derivatives were designed and synthesized as antiproliferative agents. The antiproliferative activity of these…”
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New-Generation Benzimidazole-Based Plasmid Delivery Reagents with High Transfection Efficiencies on the Mammalian Cells by Ayaz, Furkan, Ersan, Ronak Haj, Kuzu, Burak, Algul, Oztekin

“…Gene transfer and gene therapy studies require high-efficiency gene delivery reagents. By transferring the piece of DNA that we are interested in, we can alter…”
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2-Phenyl substituted Benzimidazole derivatives: Design, synthesis, and evaluation of their antiproliferative and antimicrobial activities by Ersan, Ronak Haj, Kuzu, Burak, Yetkin, Derya, Alagoz, Mehmet Abdullah, Dogen, Aylin, Burmaoglu, Serdar, Algul, Oztekin

“…The inability to meet the desired outcomes of anticancer treatment and decrease in treatment success of bacterial and fungal infections accelerated research in…”
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Bisbenzoxazole Derivatives: Design, Synthesis, in Vitro Antimicrobial, Antiproliferative Activity, and Molecular Docking Studies by Ersan, Ronak Haj, Alagoz, Mehmet Abdullah, Dogen, Aylin, Duran, Nizami, Burmaoglu, Serdar, Algul, Oztekin

“…Four series of bisbenzoxazole derivatives were designed, synthesized, and screened for antiproliferative and antimicrobial activities. Generally, all…”
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Vibrational spectrum and assignments of 2-(4-methoxyphenyl)-1H-benzo[d]imidazole by ab initio Hartree-Fock and density functional methods by Arslan, Hakan, Algül, Oztekin

“…The room temperature attenuated total reflection Fourier transform infrared spectrum of the 2-(4-methoxyphenyl)-1H-benzo[d]imidazole has been recorded with…”
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Synthesis and biological evaluation of 3,5‐diaryl‐pyrazole derivatives as potential antiprostate cancer agents by Anil, Derya, Caykoylu, Emine U., Sanli, Fatma, Gambacorta, Nicola, Karatas, Omer F., Nicolotti, Orazio, Algul, Oztekin, Burmaoglu, Serdar

“…Prostate cancer is the most frequently diagnosed tumor in men and the second leading cause of cancer‐associated mortality in most developed countries…”
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One‐pot synthesis of novel benzimidazoles with a naphthalene moiety as antimicrobial agents and molecular docking studies by Ersan, Ronak Haj, Yuksel, Ahmet, Ertan‐Bolelli, Tugba, Dogen, Aylin, Burmaoglu, Serdar, Algul, Oztekin

“…In an attempt to design a greener approach for the synthesis of a potent class of antimicrobials, 1,2‐phenylenediamine derivatives were reacted with various…”
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Design of potent fluoro-substituted chalcones as antimicrobial agents by Burmaoglu, Serdar, Algul, Oztekin, Gobek, Arzu, Aktas Anil, Derya, Ulger, Mahmut, Erturk, Busra Gul, Kaplan, Engin, Dogen, Aylin, Aslan, Gönül

“…Owing to ever-increasing bacterial and fungal drug resistance, we attempted to develop novel antitubercular and antimicrobial agents. For this purpose, we…”
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Investigation of New Benzimidazole Derivative Compounds’ Effects on A549 Cell Line by Duran, Gülay Gülbol, Küçük, Meral Urhan, Algül, Öztekin, Terzi, Menderes Yusuf

“…Abstract Chronic inflammation is a common indication of several diseases, e.g. asthma, chronic obstructive pulmonary disease (COPD), atherosclerosis, etc…”
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Synthesis, In Vitro Biological Evaluation, and Molecular Docking Studies of Novel Biphenyl Chalcone Derivatives as Antimicrobial Agents by Burmaoglu, Serdar, Akin Kazancioglu, Elif, Kazancioglu, Mustafa Z., Alagoz, Mehmet Abdullah, Dogen, Aylin, Algul, Oztekin

“…The increasing resistance to antimicrobial drugs has instigated the crucial need for the discovery of novel compounds with different modes of action that could…”
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Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives by Burmaoglu, Serdar, Gobek, Arzu, Anil, Derya Aktas, Alagoz, Mehmet Abdullah, Guner, Adem, Güler, Cem, Hepokur, Ceylan, Karabay Yavasoglu, N. Ulku, Algul, Oztekin

“…Pathological angiogenesis plays a critical role in tumorigenesis and tumor progression, and anti-angiogenesis therapies have evinced promising antitumor…”
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Comparative studies on conventional and microwave synthesis of some benzimidazole, benzothiazole and indole derivatives and testing on inhibition of hyaluronidase by Algul, Oztekin, Kaessler, Andre, Apcin, Yagmur, Yilmaz, Akin, Jose, Joachim

“…We have synthesized twelve 2-substituted benzimidazole, benzothiazole and indole derivatives using on both microwave irradiation and conventional heating…”
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Vibrational spectroscopy investigation using ab initio and density functional theory analysis on the structure of 3-(6-benzoyl-2-oxobenzo[ d]oxazol-3(2 H)-yl)propanoic acid by Arslan, Hakan, Algül, Öztekin, Önkol, Tijen

“…The molecular structure, vibrational frequencies and infrared intensities of the 3-(6-benzoyl-2-oxobenzo[ d]oxazol-3(2 H)-yl)propanoic acid were calculated by…”
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DNA base bioisosteres, bis-benzoxazoles, exert anti-proliferative effect on human prostate and breast cancer cells by Ayaz,Furkan, Kheeree,Rusmeenee, Isse,Qadar Ahmed, Ersan,Ronak Haj, Algul,Oztekin

“…A series of symmetric bis-benzoxazole derivatives were synthesized using one-pot cyclization between 4-chloro substituted 2-aminophenol and suitable…”
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