Search Results - "Alfredo G. CASANOVA"

Systematic review and meta-analysis of the efficacy of clinically tested protectants of cisplatin nephrotoxicity by Casanova, Alfredo G., Hernández-Sánchez, María Teresa, López-Hernández, Francisco J., Martínez-Salgado, Carlos, Prieto, Marta, Vicente-Vicente, Laura, Morales, Ana Isabel

“…Introduction Cisplatin is a potent antineoplastic drug that has been widely used to treat a number of solid tumors. However, a high incidence of renal damage…”
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Effect of uric acid reduction on chronic kidney disease. Systematic review and meta-analysis by Casanova, Alfredo G, Morales, Ana I, Vicente-Vicente, Laura, López-Hernández, Francisco J

“…Accumulating evidence suggests that hyperuricemia is a pathological factor in the development and progression of chronic kidney disease. However, the potential…”
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A wide scope, pan-comparative, systematic meta-analysis of the efficacy of prophylactic strategies for cardiac surgery-associated acute kidney injury by Martín-Fernández, Marta, Casanova, Alfredo G., Jorge-Monjas, Pablo, Morales, Ana I., Tamayo, Eduardo, López Hernández, Francisco J.

“…Acute kidney injury (AKI) is the most common complication of cardiac surgery. Cardiac surgery-associated AKI (CSA-AKI) is caused by systemic and renal…”
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A Micellar Formulation of Quercetin Prevents Cisplatin Nephrotoxicity by Casanova, Alfredo G, Prieto, Marta, Colino, Clara I, Gutiérrez-Millán, Carmen, Ruszkowska-Ciastek, Barbara, de Paz, Esther, Martín, Ángel, Morales, Ana I, López-Hernández, Francisco J

“…The antioxidant flavonoid quercetin has been shown to prevent nephrotoxicity in animal models and in a clinical study and is thus a very promising prophylactic…”
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Protective Effect of Quercetin 3- O -Glucuronide against Cisplatin Cytotoxicity in Renal Tubular Cells by Muñoz-Reyes, Daniel, Casanova, Alfredo G, González-Paramás, Ana María, Martín, Ángel, Santos-Buelga, Celestino, Morales, Ana I, López-Hernández, Francisco J, Prieto, Marta

“…Quercetin, a flavonoid with promising therapeutic potential, has been shown to protect from cisplatin nephrotoxicity in rats following intraperitoneal…”
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Identification of Pre-Renal and Intrinsic Acute Kidney Injury by Anamnestic and Biochemical Criteria: Distinct Association with Urinary Injury Biomarkers by Sancho-Martínez, Sandra M, Casanova, Alfredo G, Düwel, Annette G, Rivero-García, Karen, García-Garrido, Tamara, Morales, Ana I, Martínez-Salgado, Carlos, López-Hernández, Francisco J, Fraile, Pilar

“…Acute kidney injury (AKI) is a syndrome of sudden renal excretory dysfunction with severe health consequences. AKI etiology influences prognosis, with…”
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Urinary transferrin pre-emptively identifies the risk of renal damage posed by subclinical tubular alterations by Casanova, Alfredo G., Vicente-Vicente, Laura, Hernández-Sánchez, M. Teresa, Prieto, Marta, Rihuete, M. Isabel, Ramis, Laura M., del Barco, Elvira, Cruz, Juan J., Ortiz, Alberto, Cruz-González, Ignacio, Martínez-Salgado, Carlos, Pescador, Moisés, López-Hernández, Francisco J., Morales, Ana I.

“…Nephrotoxicity is an important limitation to the clinical use of many drugs and contrast media. Drug nephrotoxicity occurs in acute, subacute and chronic…”
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New Challenges in the Diagnosis of Kidney Damage Due to Immune Checkpoint Inhibitors Therapy: An Observational Clinical Study by Vicente-Vicente, Laura, Casanova, Alfredo G, Tascón, Javier, Prieto, Marta, Morales, Ana I

“…In recent years, immunotherapy has been postulated as one of the most effective strategies in the fight against cancer. The greatest success in this field has…”
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Are Antioxidants Useful in Preventing the Progression of Chronic Kidney Disease? by Casanova, Alfredo G., López-Hernández, Francisco J., Vicente-Vicente, Laura, Morales, Ana I.

“…Chronic kidney disease (CKD) is a progressive impairment of renal function for more than three months that affects 15% of the adult population. Because…”
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Neural Network-Based Calculator for Rat Glomerular Filtration Rate by Pellicer-Valero, Óscar J, Massaro, Giampiero A, Casanova, Alfredo G, Paniagua-Sancho, María, Fuentes-Calvo, Isabel, Harvat, Mykola, Martín-Guerrero, José D, Martínez-Salgado, Carlos, López-Hernández, Francisco J

“…Glomerular filtration is a pivotal process of renal physiology, and its alterations are a central pathological event in acute kidney injury and chronic kidney…”
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Regression Modeling of the Antioxidant-to-Nephroprotective Relation Shows the Pivotal Role of Oxidative Stress in Cisplatin Nephrotoxicity by Casanova, Alfredo G., Harvat, Mykola, Vicente-Vicente, Laura, Pellicer-Valero, Óscar J., Morales, Ana I., López-Hernández, Francisco J., Martín-Guerrero, José D.

“…The clinical utility of the chemotherapeutic drug cisplatin is significantly limited by its nephrotoxicity, which is characterized by electrolytic disorders,…”
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Hepatotoxicity due to dietary supplements: state-of-the-art, gaps and perspectives by Rivero-Pino, Fernando, Casanova, Alfredo G

“…Food supplements are products intended to complement the normal diet and consist of concentrated sources of nutrients or other substances with a nutritional or…”
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Designing new diagnostic systems for the early detection of tobacco-associated chronic renal damage in patients of a primary care centre in Salamanca, Spain: an observational, prospective study protocol by Prieto, Marta, Vicente-Vicente, Laura, Casanova, Alfredo G, Hernández-Sánchez, Maria Teresa, Gomez-Marcos, Manuel A, Garcia-Ortiz, Luis, Morales, Ana Isabel

“…IntroductionTobacco causes kidney damage that can progress to chronic kidney disease. However, the diagnostic parameters used in clinics are not effective in…”
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Urinary GM2AP coincides with renal cortical damage and grades cisplatin nephrotoxicity severity in rats by Blanco-Gozalo, Víctor, Quiros, Yaremi, Vicente-Vicente, Laura, Casanova, Alfredo G., Sancho-Martínez, Sandra M., López-Hernández, Francisco J.

“…Nephrotoxicity, including electrolytic disorders and acute kidney injury (AKI), limits the clinical dosage and utility of platinated antineoplastics such as…”
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Oxidative stress and renal status of farmers exposed to pesticides in Seville (Spain) by Casanova, Alfredo G., Hinojosa, María G., Chamorro-López, Carmen, Martín-Reina, José, Aguilera-Velázquez, Raúl, Bautista, Juan D., Morales, Ana I., Moreno, Isabel M.

“…The aim was to determine whether indirect exposure to pesticides, specifically a copper-based fungicide, induces alterations in oxidative stress and…”
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Corrigendum to ‘P-Glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: Ex vivo and in vivo studies’ [Toxicology and Applied Pharmacology 386 (2020) 114832] by Rocha-Pereira, Carolina, Ghanem, Carolina Inés, Silva, Renata, Casanova, Alfredo G., Duarte-Araújo, Margarida, Gonçalves-Monteiro, Salomé, Sousa, Emília, de Lourdes Bastos, Maria, Remião, Fernando

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Adverse Health Effects in Women Farmers Indirectly Exposed to Pesticides by Martin-Reina, Jose, Casanova, Alfredo G., Dahiri, Bouchra, Fernández, Isaías, Fernández-Palacín, Ana, Bautista, Juan, Morales, Ana I., Moreno, Isabel

“…Farmers are among the most vulnerable populations because of the exposure to low levels of pesticides. Acetylcholinesterase and butyrylcholinesterase…”
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A meta-analysis of preclinical studies using antioxidants for the prevention of cisplatin nephrotoxicity: implications for clinical application by Casanova, Alfredo G., Hernández-Sánchez, M. Teresa, Martínez-Salgado, Carlos, Morales, Ana I., Vicente-Vicente, Laura, López-Hernández, Francisco J.

“…Cisplatin is an effective chemotherapeutic drug whose clinical use and efficacy are limited by its nephrotoxicity, which affects mainly the renal tubules and…”
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The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats by Casanova, Alfredo G., Fuentes-Calvo, Isabel, Hernández-Sánchez, María T., Quintero, Miguel, Toral, Paula, Caballero, María T., Martínez-Salgado, Carlos, Morales, Ana I., Layton, Anita T., Eleno, Nélida, López-Hernández, Francisco J.

“…Acute kidney injury (AKI) diagnosis relies on plasma creatinine concentration (Crpl), a relatively insensitive, surrogate biomarker of glomerular filtration…”
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Key role of oxidative stress in animal models of aminoglycoside nephrotoxicity revealed by a systematic analysis of the antioxidant-to-nephroprotective correlation by CASANOVA, Alfredo G, VICENTE-VICENTE, Laura, HERNÁNDEZ-SÁNCHEZ, María Teresa, PESCADOR, Moisés, PRIETO, Marta, MARTÍNEZ-SALGADO, Carlos, MORALES, Ana I, LÓPEZ-HERNÁNDEZ, Francisco J

“…Abstract The clinical utility of aminoglycoside antibiotics is partly limited by their nephrotoxicity. Co-administration of a variety of candidate…”
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